Aliases for HAO2 Gene
External Ids for HAO2 Gene
Previous GeneCards Identifiers for HAO2 Gene
This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for HAO2 Gene
HAO2 (Hydroxyacid Oxidase 2) is a Protein Coding gene. Diseases associated with HAO2 include Histidinemia and Histidine Metabolism Disease. Among its related pathways are Glyoxylate and dicarboxylate metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and FMN binding. An important paralog of this gene is HAO1.
UniProtKB/Swiss-Prot Summary for HAO2 Gene
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids.