Aliases for HAND2-AS1 Gene

Subcategory (RNA class) for HAND2-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for HAND2-AS1 Gene

  • HAND2 Antisense RNA 1 2 3 5
  • Differentially Expressed In Neuroblastoma 2 3
  • HAND2 Antisense RNA 1 (Head To Head) 2 3
  • Neuroblastoma Transcript 301 2 3
  • HAND2-AS1 2 168
  • HSALNG0038609 167
  • NONHSAG039361 92
  • NONHSAG039362 92
  • Lnc-SAP30-23 168
  • NBLA00301 3
  • DEIN 3
  • UPH 3

External Ids for HAND2-AS1 Gene

Previous GeneCards Identifiers for HAND2-AS1 Gene

  • GC04P174448

Summaries for HAND2-AS1 Gene

GeneCards Summary for HAND2-AS1 Gene

HAND2-AS1 (HAND2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with HAND2-AS1 include Right Ventricular Hypoplasia, Isolated and Endometrial Cancer.

Additional gene information for HAND2-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HAND2-AS1 Gene

Genomics for HAND2-AS1 Gene

GeneHancer (GH) Regulatory Elements for HAND2-AS1 Gene

Promoters and enhancers for HAND2-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for HAND2-AS1 Gene

Genomic Locations for HAND2-AS1 Gene
chr4:173,527,270-173,659,696
(GRCh38/hg38)
Size:
132,427 bases
Orientation:
Plus strand
chr4:174,448,421-174,512,475
(GRCh37/hg19)
Size:
64,055 bases
Orientation:
Plus strand

Genomic View for HAND2-AS1 Gene

Genes around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAND2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAND2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAND2-AS1 Gene

Proteins for HAND2-AS1 Gene

Post-translational modifications for HAND2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAND2-AS1 Gene

Domains & Families for HAND2-AS1 Gene

Gene Families for HAND2-AS1 Gene

Suggested Antigen Peptide Sequences for HAND2-AS1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ11539 fis, clone HEMBA1002748 (Q9HAJ2_HUMAN)
genes like me logo Genes that share domains with HAND2-AS1: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for HAND2-AS1 Gene

Function for HAND2-AS1 Gene

Phenotypes From GWAS Catalog for HAND2-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAND2-AS1 Gene

Localization for HAND2-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HAND2-AS1 gene
Compartment Confidence
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HAND2-AS1 Gene

Pathways & Interactions for HAND2-AS1 Gene

PathCards logo

SuperPathways for HAND2-AS1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for HAND2-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for HAND2-AS1 Gene

Drugs & Compounds for HAND2-AS1 Gene

No Compound Related Data Available

Transcripts for HAND2-AS1 Gene

mRNA/cDNA for HAND2-AS1 Gene

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for HAND2-AS1 Gene

No ASD Table

Relevant External Links for HAND2-AS1 Gene

GeneLoc Exon Structure for
HAND2-AS1

Expression for HAND2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HAND2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HAND2-AS1 Gene

This gene is overexpressed in Colon - Sigmoid (x9.3) and Uterus (x4.7).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HAND2-AS1

genes like me logo Genes that share expression patterns with HAND2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HAND2-AS1 Gene

Orthologs for HAND2-AS1 Gene

Evolution for HAND2-AS1 Gene

ENSEMBL:
Gene Tree for HAND2-AS1 (if available)
TreeFam:
Gene Tree for HAND2-AS1 (if available)

No data available for Orthologs for HAND2-AS1 Gene

Paralogs for HAND2-AS1 Gene

No data available for Paralogs for HAND2-AS1 Gene

Variants for HAND2-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HAND2-AS1 Gene

SNP ID Clinical significance and condition Chr 04 pos Variation AA Info Type
750314 Likely Benign: not provided 173,529,176(+) C/T SYNONYMOUS_VARIANT
rs1553974835 Pathogenic: Dilated cardiomyopathy 1A 173,529,091(+) C/A NONSENSE
rs483353128 Likely Pathogenic: not provided 173,528,900(+) G/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for HAND2-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for HAND2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv518998 CNV loss 19592680
nsv522261 CNV loss 19592680

Additional Variant Information for HAND2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAND2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAND2-AS1 Gene

Disorders for HAND2-AS1 Gene

MalaCards: The human disease database

(5) MalaCards diseases for HAND2-AS1 Gene - From: LncRNADisease, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for HAND2-AS1

genes like me logo Genes that share disorders with HAND2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HAND2-AS1 Gene

Publications for HAND2-AS1 Gene

  1. Recurrently deregulated lncRNAs in hepatocellular carcinoma. (PMID: 28194035) Yang Y … Lu ZJ (Nature communications 2017) 2 3 54
  2. Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. (PMID: 19348682) Voth H … Fischer M (BMC molecular biology 2009) 2 3 54
  3. Identification of DEIN, a novel gene with high expression levels in stage IVS neuroblastoma. (PMID: 18171985) Voth H … Fischer M (Molecular cancer research : MCR 2007) 2 3 54
  4. LncRNA HAND2-AS1 inhibits non-small cell lung cancer migration, invasion and maintains cell stemness through the interactions with TGF-β1. (PMID: 30509963) Miao F … Pang L (Bioscience reports 2019) 3 54
  5. LncRNA HAND2-AS1 sponging miR-1275 suppresses colorectal cancer progression by upregulating KLF14. (PMID: 30078677) Zhou J … Xie R (Biochemical and biophysical research communications 2018) 3 54

Products for HAND2-AS1 Gene

Sources for HAND2-AS1 Gene