External Ids for HAL Gene
Previous HGNC Symbols for HAL Gene
Previous GeneCards Identifiers for HAL Gene
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
GeneCards Summary for HAL Gene
HAL (Histidine Ammonia-Lyase) is a Protein Coding gene. Diseases associated with HAL include Histidinemia and Histidine Metabolism Disease. Among its related pathways are histidine degradation and Metabolism. Gene Ontology (GO) annotations related to this gene include histidine ammonia-lyase activity and ammonia-lyase activity.