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Aliases for HAGLR Gene

Subcategory (RNA class) for HAGLR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HAGLR Gene

  • HOXD Antisense Growth-Associated Long Non-Coding RNA 2 3 5
  • HOXD Cluster Antisense RNA 1 (Non-Protein Coding) 2 3
  • HOXD Cluster Antisense RNA 1 2
  • HOXD-AS1 3
  • Mdgt 3

External Ids for HAGLR Gene

Previous HGNC Symbols for HAGLR Gene

  • HOXD-AS1

Summaries for HAGLR Gene

GeneCards Summary for HAGLR Gene

HAGLR (HOXD Antisense Growth-Associated Long Non-Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for HAGLR Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HAGLR Gene

Genomics for HAGLR Gene

GeneHancer (GH) Regulatory Elements for HAGLR Gene

Promoters and enhancers for HAGLR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I176186 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 550.8 +0.6 623 2.9 FOXA2 ZFP64 SIN3A DMAP1 GLI4 ZNF2 ZNF48 GLIS2 KLF7 ZNF202 HOXD1 HAGLR MIR7704 HAGLROS
GH02I176128 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 20.7 +54.2 54168 13.3 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ZNF213 E2F8 HOXD8 HOXD3 HOXD1 HAGLR ATF2 HOXD4 HOXD9 HAGLROS HOXD11 HOXD-AS2
GH02I176159 Enhancer 0.5 ENCODE 27.3 +27.7 27745 3 ELF3 USF1 SUZ12 CTBP2 USF2 PRDM4 EZH2 HAGLROS HAGLR HOXD1 HOXD-AS2 HOXD9 HOXD3 HOXD8 HOXD10 HOXD11 HOXD13
GH02I176177 Enhancer 0.9 Ensembl ENCODE 15 +10.5 10540 2.2 CTCF USF1 ZNF777 SUZ12 JUN MAX E2F1 ZFHX2 CTBP1 EGR2 HAGLROS HAGLR HOXD1 HOXD4 HOXD3 HOXD-AS2 MIR10B HOXD11 HOXD12 HOXD10
GH02I176552 Enhancer 1.3 FANTOM5 Ensembl ENCODE 10.2 -364.7 -364733 3 ARNT FEZF1 ZNF2 ZBTB7B YY1 ZNF280A E2F8 ZNF143 ATF7 RUNX3 HNRNPA3 HOXD4 HOXD3 HOXD-AS2 MIR10B HAGLR HOXD1 HOXD13 ENSG00000236231 GC02P176590
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HAGLR on UCSC Golden Path with GeneCards custom track

Genomic Locations for HAGLR Gene

Genomic Locations for HAGLR Gene
chr2:176,173,189-176,188,958
(GRCh38/hg38)
Size:
15,770 bases
Orientation:
Minus strand
chr2:177,037,923-177,053,686
(GRCh37/hg19)

Genomic View for HAGLR Gene

Genes around HAGLR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAGLR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAGLR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAGLR Gene

Proteins for HAGLR Gene

Post-translational modifications for HAGLR Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAGLR Gene

Domains & Families for HAGLR Gene

Gene Families for HAGLR Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HAGLR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HAGLR Gene

Function for HAGLR Gene

Phenotypes From GWAS Catalog for HAGLR Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAGLR Gene

Localization for HAGLR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HAGLR Gene

Pathways & Interactions for HAGLR Gene

SuperPathways for HAGLR Gene

No Data Available

Interacting Proteins for HAGLR Gene

Gene Ontology (GO) - Biological Process for HAGLR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HAGLR Gene

Drugs & Compounds for HAGLR Gene

No Compound Related Data Available

Transcripts for HAGLR Gene

mRNA/cDNA for HAGLR Gene

(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HAGLR Gene

No ASD Table

Relevant External Links for HAGLR Gene

GeneLoc Exon Structure for
HAGLR
ECgene alternative splicing isoforms for
HAGLR

Expression for HAGLR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HAGLR Gene

NURSA nuclear receptor signaling pathways regulating expression of HAGLR Gene:

HAGLR
genes like me logo Genes that share expression patterns with HAGLR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HAGLR Gene

Orthologs for HAGLR Gene

Evolution for HAGLR Gene

ENSEMBL:
Gene Tree for HAGLR (if available)
TreeFam:
Gene Tree for HAGLR (if available)

No data available for Orthologs for HAGLR Gene

Paralogs for HAGLR Gene

No data available for Paralogs for HAGLR Gene

Variants for HAGLR Gene

Sequence variations from dbSNP and Humsavar for HAGLR Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000498648 -- 176,183,382(-) G/A genic_upstream_transcript_variant, intron_variant
rs1000552241 -- 176,182,995(-) G/A genic_upstream_transcript_variant, intron_variant
rs1000929407 -- 176,176,214(-) G/A non_coding_transcript_variant
rs1000981774 -- 176,176,419(-) T/C non_coding_transcript_variant
rs1001145882 -- 176,177,161(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HAGLR Gene

Variant ID Type Subtype PubMed ID
nsv1001933 CNV gain 25217958
dgv676n67 CNV gain 20364138

Additional Variant Information for HAGLR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAGLR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAGLR Gene

Disorders for HAGLR Gene

Additional Disease Information for HAGLR

No disorders were found for HAGLR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HAGLR Gene

Publications for HAGLR Gene

  1. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. (PMID: 24381249) Sauvageau M … Rinn JL (eLife 2013) 2 3 58
  2. Role of genomic architecture in the expression dynamics of long noncoding RNAs during differentiation of human neuroblastoma cells. (PMID: 24555823) Batagov AO … Kurochkin IV (BMC systems biology 2013) 2 3 58
  3. Knockdown of long non-coding RNA HOXD-AS1 inhibits gastric cancer cell growth via inactivating the JAK2/STAT3 pathway. (PMID: 28475004) Zheng L … He Z (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  4. Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis. (PMID: 28443464) Lu C … Cai D (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  5. Synthetic tetracycline-controllable shRNA targeting long non-coding RNA HOXD-AS1 inhibits the progression of bladder cancer. (PMID: 27328915) Li J … Huang W (Journal of experimental & clinical cancer research : CR 2016) 3 58

Products for HAGLR Gene

Sources for HAGLR Gene

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