Aliases for HAGH Gene
External Ids for HAGH Gene
Previous GeneCards Identifiers for HAGH Gene
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
GeneCards Summary for HAGH Gene
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. Diseases associated with HAGH include Hydroxyacyl Glutathione Hydrolase Deficiency and Encephalopathy, Ethylmalonic. Among its related pathways are Pyruvate metabolism and Citric Acid (TCA) cycle and Metabolism. Gene Ontology (GO) annotations related to this gene include hydroxyacylglutathione hydrolase activity. An important paralog of this gene is HAGHL.
UniProtKB/Swiss-Prot Summary for HAGH Gene
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.