Aliases for H6PD Gene
External Ids for H6PD Gene
Previous HGNC Symbols for H6PD Gene
Previous GeneCards Identifiers for H6PD Gene
There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for H6PD Gene
H6PD (Hexose-6-Phosphate Dehydrogenase/Glucose 1-Dehydrogenase) is a Protein Coding gene. Diseases associated with H6PD include Cortisone Reductase Deficiency 1 and Hyperandrogenism Due To Cortisone Reductase Deficiency. Among its related pathways are Carbon metabolism and Pentose phosphate pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and glucose-6-phosphate dehydrogenase activity. An important paralog of this gene is G6PD.
UniProtKB/Swiss-Prot Summary for H6PD Gene
Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.