Aliases for H6PD Gene
External Ids for H6PD Gene
Previous HGNC Symbols for H6PD Gene
Previous GeneCards Identifiers for H6PD Gene
There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for H6PD Gene
H6PD (Hexose-6-Phosphate Dehydrogenase/Glucose 1-Dehydrogenase) is a Protein Coding gene. Diseases associated with H6PD include Cortisone Reductase Deficiency 1 and Hyperandrogenism Due To Cortisone Reductase Deficiency. Among its related pathways are Pentose phosphate pathway and Metabolism. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and glucose-6-phosphate dehydrogenase activity. An important paralog of this gene is G6PD.
UniProtKB/Swiss-Prot for H6PD Gene
Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.