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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and ... See more...
Aliases for H2BC6 Gene
Aliases for H2BC6 Gene
- H2B Clustered Histone 6 2 3 5
- H2B/H 2 3 4
- Histone Cluster 1 H2B Family Member E 2 3
- H2B Histone Family, Member H 2 3
- Histone H2B Type 1-C/E/F/G/I 3 4
- Histone Cluster 1, H2be 2 3
- Histone 1, H2be 2 3
- Histone H2B.1 A 3 4
- Histone H2B.H 3 4
- HIST1H2BE 3 4
- H2B.H 2 3
- H2BFH 3 4
- Histone H2B.A 4
- Histone H2B.G 4
- Histone H2B.K 4
- Histone H2B.L 4
- DJ221C16.8 3
External Ids for H2BC6 Gene
- HGNC: 4753
- Entrez Gene: 8344
- Ensembl: ENSG00000274290
- OMIM: 602805
- UniProtKB: P62807
Previous HGNC Symbols for H2BC6 Gene
- H2BFH
- HIST1H2BE
Previous GeneCards Identifiers for H2BC6 Gene
- GC06P027654
- GC06P028383
Summaries for H2BC6 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2BC6 Gene
H2BC6 (H2B Clustered Histone 6) is a Protein Coding gene. Diseases associated with H2BC6 include Ehrlich Tumor Carcinoma. Among its related pathways are Chromatin organization and Signaling by GPCR. An important paralog of this gene is H2BC7.
UniProtKB/Swiss-Prot Summary for H2BC6 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-
Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Additional gene information for H2BC6 Gene
- HGNC(4753)
- Entrez Gene(8344)
- Ensembl(ENSG00000274290)
- OMIM(602805)
- UniProtKB(P62807)
- Open Targets Platform(ENSG00000274290)
- Search for H2BC6 at DataMed
- Search for H2BC6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2BC6 Gene
Genomics for H2BC6 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2BC6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2BC6 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2BC6
Genomic Locations for H2BC6 Gene
Genomic Locations for H2BC6 Gene
- chr6:26,172,059-26,184,655
- (GRCh38/hg38)
- Size:
- 12,597 bases
- Orientation:
- Plus strand
- chr6:26,183,958-26,184,458
- (GRCh37/hg19)
- Size:
- 501 bases
- Orientation:
- Plus strand
Genomic View for H2BC6 Gene
Genes around H2BC6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by HGNC
- 6p22.2 by Entrez Gene
- 6p22.2 by Ensembl
H2BC6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2BC6 Gene
Proteins for H2BC6 Gene
-
Protein details for H2BC6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P62807-H2B1C_HUMAN
- Recommended name:
- Histone H2B type 1-C/E/F/G/I
- Protein Accession:
- P62807
- P02278
- Q3B872
- Q4VB69
- Q93078
- Q93080
Protein attributes for H2BC6 Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13906 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2BC6 Gene
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes.
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Glycosylation at Ser113
- NX_P62807 (NX_P62807-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2BC6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Biorbyt antibodies for H2BC6
Protein Products
-
OriGene Purified Proteins for H2BC6
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC6
- Origene Custom Protein Services for H2BC6
- Novus Biologicals lysates for H2BC6
No data available for DME Specific Peptides for H2BC6 Gene
Domains & Families for H2BC6 Gene
Gene Families for H2BC6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for H2BC6 Gene
- InterPro:
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
P62807- Family:
-
- Belongs to the histone H2B family.
No data available for Suggested Antigen Peptide Sequences for H2BC6 Gene
Function for H2BC6 Gene
Molecular function for H2BC6 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- UniProtKB/Swiss-Prot Function:
- Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Phenotypes From GWAS Catalog for H2BC6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA,NAS | 422550 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0042802 | identical protein binding | IPI | 25954010 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2BC6 Gene
- GenomeRNAi human phenotypes for H2BC6:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC6 - Select products 50% OFF >
- * H2BC6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2BC6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC6
miRNA for H2BC6 Gene
- miRTarBase miRNAs that target H2BC6
-
- hsa-miR-34a-5p (MIRT025218)
- hsa-miR-98-5p (MIRT027455)
- hsa-miR-146a-3p (MIRT360268)
- hsa-miR-760 (MIRT360269)
- hsa-miR-1276 (MIRT360270)
- hsa-miR-3940-5p (MIRT360274)
- hsa-miR-4507 (MIRT360275)
- hsa-miR-6839-3p (MIRT360277)
- hsa-miR-8057 (MIRT360278)
- hsa-miR-5693 (MIRT511726)
- hsa-miR-3115 (MIRT511727)
- hsa-miR-4758-5p (MIRT511728)
- hsa-miR-1238-5p (MIRT511729)
- hsa-miR-299-5p (MIRT511730)
- hsa-miR-629-5p (MIRT511731)
- hsa-miR-6822-3p (MIRT511732)
- hsa-miR-4745-5p (MIRT511733)
- hsa-miR-4481 (MIRT511734)
- hsa-miR-4766-5p (MIRT511735)
- mmu-miR-692 (MIRT594407)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC6
- Browse OriGene Inhibitory RNA Products For H2BC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC6
Clone Products
- Applied Biological Materials (abm): Clones for H2BC6 - Select products 50% OFF >
- * H2BC6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2BC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC6
Cell Line Products
-
Horizon Cell Lines for H2BC6
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2BC6 Gene
Localization for H2BC6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2BC6 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | NAS | 422550 |
| GO:0005615 | extracellular space | IDA | 12860195 |
| GO:0005634 | nucleus | IEA,HDA | 21630459 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for H2BC6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.35
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence (REACTOME) | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for H2BC6 Gene
68 Reactome pathways for H2BC6 Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for H2BC6 Gene
1 GeneGo (Thomson Reuters) pathway for H2BC6 Gene
- Signal transduction Activin A signaling regulation
Interacting Proteins for H2BC6 Gene
Selected Interacting proteins:
P62807-H2B1C_HUMAN
ENSP00000483237
for H2BC6 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for H2BC6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002227 | innate immune response in mucosa | IDA | 12860195 |
| GO:0006334 | nucleosome assembly | IBA,NAS | 422550 |
| GO:0016567 | protein ubiquitination | TAS | -- |
| GO:0019731 | antibacterial humoral response | IDA | 12860195 |
| GO:0042742 | defense response to bacterium | IEA | -- |
No data available for SIGNOR curated interactions for H2BC6 Gene
Transcripts for H2BC6 Gene
mRNA/cDNA for H2BC6 Gene
- 1 REFSEQ mRNAs :
- 2 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000614097 470 nts (view in UCSC)
- ENST00000634910 2585 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC6 - Select products 50% OFF >
- * H2BC6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2BC6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC6
- Browse OriGene Inhibitory RNA Products For H2BC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC6
Clone Products
- Applied Biological Materials (abm): Clones for H2BC6 - Select products 50% OFF >
- * H2BC6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2BC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC6
Relevant External Links for H2BC6 Gene
- GeneLoc Exon Structure for
- H2BC6
Expression for H2BC6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2BC6
SOURCE GeneReport for Unigene cluster for H2BC6 Gene:
Hs.534369Evidence on tissue expression from TISSUES for H2BC6 Gene
- Spleen(4.6)
- Lung(4.4)
- Intestine(2.9)
- Blood(2.4)
- Nervous system(2.3)
Primer Products
-
OriGene qPCR primer pairs for H2BC6
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2BC6 Gene
Orthologs for H2BC6 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Mouse (Mus musculus) |
Mammalia | Hist1h2bl 30 |
|
||
| H2bc13 17 |
|
||||
| Dog (Canis familiaris) |
Mammalia | LOC100856116 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | HIST1H2BL 30 |
|
||
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC471883 30 |
|
- Species where no ortholog for H2BC6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for H2BC6 Gene
- ENSEMBL:
- Gene Tree for H2BC6 (if available)
- TreeFam:
- Gene Tree for H2BC6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2BC6: view image
Paralogs for H2BC6 Gene
Variants for H2BC6 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv375n21 | CNV | loss | 19592680 |
| dgv5926n100 | CNV | gain | 25217958 |
| nsv1023453 | CNV | gain | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
| nsv970084 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
58.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.80;
89.52% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2BC6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- H2BC6
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2BC6 Gene
Disorders for H2BC6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ehrlich tumor carcinoma |
|
|
Search H2BC6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for H2BC6
No data available for UniProtKB/Swiss-Prot and Genatlas for H2BC6 Gene
Publications for H2BC6 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- Human histone gene organization: nonregular arrangement within a large cluster. (PMID: 9119399) Albig W … Doenecke D (Genomics 1997) 2 3 4
- Quantitative proteomic analysis of post-translational modifications of human histones. (PMID: 16627869) Beck HC … Jensen ON (Molecular & cellular proteomics : MCP 2006) 3 4
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R … Reinberg D (Cell 2006) 3 4
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (PMID: 16307923) Zhu B … Reinberg D (Molecular cell 2005) 3 4
ExternalLinks
Products for H2BC6 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H2BC6
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC6
- Origene Custom Protein Services for H2BC6
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC6
- Browse OriGene Inhibitory RNA Products For H2BC6
- OriGene qPCR primer pairs for H2BC6
- OriGene CRISPR knockouts for H2BC6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2BC6
- Sino Biological Human cDNA Clone for H2BC6
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals lysates for H2BC6
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder Custom and pre-made DNA vectors for H2BC6 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2BC6 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2BC6 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2BC6 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2BC6
- antibodies-online: Search results for available HIST1H2BE related products ranked by validation data
- antibodies-online: Search results for available HIST1H2BE related products ranked by validation data
- antibodies-online: Search results for available HIST1H2BE related products ranked by validation data
- Horizon Cell Lines for H2BC6
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC6
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2BC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC6
- Biorbyt antibodies for H2BC6
Sources for H2BC6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
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