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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with... See more...
Aliases for H2BC3 Gene
Aliases for H2BC3 Gene
External Ids for H2BC3 Gene
- HGNC: 4751
- NCBI Entrez Gene: 3018
- Ensembl: ENSG00000276410
- OMIM®: 602803
- UniProtKB/Swiss-Prot: P33778
Previous HGNC Symbols for H2BC3 Gene
- H2BFF
- HIST1H2BB
Summaries for H2BC3 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2BC3 Gene
H2BC3 (H2B Clustered Histone 3) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Cellular Senescence (REACTOME). An important paralog of this gene is H2BC15.
UniProtKB/Swiss-Prot Summary for H2BC3 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Additional gene information for H2BC3 Gene
- HGNC (4751)
- NCBI Entrez Gene (3018)
- Ensembl (ENSG00000276410)
- OMIM® (602803)
- UniProtKB/Swiss-Prot (P33778)
- Open Targets Platform(ENSG00000276410)
- Alliance of Genome Resources
- Search for H2BC3 at DataMed
- Search for H2BC3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2BC3 Gene
Genomics for H2BC3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2BC3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J026042 | Promoter/Enhancer | 2 | Ensembl ENCODE CraniofacialAtlas dbSUPER | 250.7 | -1.0 | -978 | 5 | BCLAF1 SP1 ZNF207 SSRP1 ZNF592 POLR2A CEBPA CHD4 YY1 MXD4 | H2AC5P H2BC3 H3C3 lnc-HIST1H3C-1 ENSG00000272462 ABT1 BTN2A2 HMGN4 BTN2A3P BTN3A2 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2BC3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2BC3
Genomic Locations for H2BC3 Gene
Latest Assembly
- chr6:26,043,227-26,043,713
- (GRCh38/hg38)
- Size:
- 487 bases
- Orientation:
- Minus strand
Previous Assembly
- chr6:26,043,455-26,043,941
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 487 bases
- Orientation:
- Minus strand
Genomic View for H2BC3 Gene
Genes around H2BC3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by HGNC
- 6p22.2 by Entrez Gene
- 6p22.2 by Ensembl
H2BC3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2BC3 Gene
Proteins for H2BC3 Gene
-
Protein details for H2BC3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P33778-H2B1B_HUMAN
- Recommended name:
- Histone H2B type 1-B
- Protein Accession:
- P33778
- Q4KN36
Protein attributes for H2BC3 Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13950 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2BC3 Gene
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes (By similarity).
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Glycosylation at Ser113
- NX_P33778 (NX_P33778-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2BC3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for H2BC3
- Invitrogen Antibodies for H2BC3 (AFLGC-H2BC3)
-
Custom Antibody ServicesProSci Antibodies for H2BC3
- Sino Biological Antibodies for H2BC3
Protein products for research
-
OriGene Purified Proteins for H2BC3
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC3
- Origene Custom Protein Services for H2BC3
- Novus Biologicals lysates for H2BC3
Assay products for research
- G Biosciences Immunotag™ Human HIST1H2BB (Histone H2B type 1-B) ELISA
- antibodies-online: Show 3 available HIST1H2BB Elisa Kits ranked by validation data
- Compare Top HIST1H2BB Elisa Kits
-
Quality Products:
-
Boster Bio ELISA Kits for H2BC3
No data available for DME Specific Peptides for H2BC3 Gene
Domains & Families for H2BC3 Gene
Gene Families for H2BC3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for H2BC3 Gene
- InterPro:
Suggested Antigen Peptide Sequences for H2BC3 Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H2B.f (H2B1B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P33778- Family:
-
- Belongs to the histone H2B family.
Function for H2BC3 Gene
Molecular function for H2BC3 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phenotypes From GWAS Catalog for H2BC3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA,NAS | 9439656 |
| GO:0005515 | protein binding | IPI | 22720776 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2BC3 Gene
- GenomeRNAi human phenotypes for H2BC3:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Increased Nanog expression
- Increased Sindbis virus (SINV) infection
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for H2BC3 - Starting at $85 >
- * H2BC3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H2BC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
miRNA for H2BC3 Gene
- miRTarBase miRNAs that target H2BC3
-
- hsa-miR-34a-5p (MIRT025273)
- hsa-miR-652-3p (MIRT039494)
- hsa-miR-196a-5p (MIRT048188)
- hsa-miR-760 (MIRT360243)
- hsa-miR-6822-3p (MIRT360247)
- hsa-miR-5693 (MIRT511736)
- hsa-miR-6839-3p (MIRT511737)
- hsa-miR-4507 (MIRT511738)
- hsa-miR-3940-5p (MIRT511739)
- hsa-miR-8057 (MIRT511740)
- hsa-miR-6079 (MIRT511741)
- hsa-miR-629-5p (MIRT511742)
- hsa-miR-4766-5p (MIRT511743)
- hsa-miR-146a-3p (MIRT511744)
- hsa-miR-1276 (MIRT511745)
- hsa-miR-6802-5p (MIRT523237)
- hsa-miR-6865-5p (MIRT523238)
- hsa-miR-6815-5p (MIRT523239)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Clone products for research
- Applied Biological Materials (abm): Clones for H2BC3 - Starting at $45 >
- * H2BC3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for H2BC3
- Addgene plasmids for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
Cell Lines for research
-
Horizon Cell Lines for H2BC3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2BC3 Gene
Localization for H2BC3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2BC3 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000781 | chromosome, telomeric region | HDA | 19135898 |
| GO:0000786 | nucleosome | NAS | 9439656 |
| GO:0005634 | nucleus | IEA,IDA | 16319397 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for H2BC3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.35
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence (REACTOME) | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for H2BC3 Gene
68 Reactome pathways for H2BC3 Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
4 KEGG pathways for H2BC3 Gene
1 GeneGo (Thomson Reuters) pathway for H2BC3 Gene
- Signal transduction Activin A signaling regulation
2 Cell Signaling Technology pathways for H2BC3 Gene
Interacting Proteins for H2BC3 Gene
Selected Interacting proteins:
P33778-H2B1B_HUMAN
ENSP00000482674
for H2BC3 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for H2BC3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006334 | nucleosome assembly | IBA,NAS | 9439656 |
| GO:0016567 | protein ubiquitination | TAS | -- |
Transcripts for H2BC3 Gene
mRNA/cDNA for H2BC3 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000615966 487 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for H2BC3 - Starting at $85 >
- * H2BC3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H2BC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Clone products for research
- Applied Biological Materials (abm): Clones for H2BC3 - Starting at $45 >
- * H2BC3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for H2BC3
- Addgene plasmids for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
Relevant External Links for H2BC3 Gene
- GeneLoc Exon Structure for
- H2BC3
Expression for H2BC3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Choroid Plexus Progenitor Cells Choroid Plexus
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2BC3
SOURCE GeneReport for Unigene cluster for H2BC3 Gene:
Hs.553494Primer products for research
-
OriGene qPCR primer pairs for H2BC3
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2BC3 Gene
Orthologs for H2BC3 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Mouse (Mus musculus) |
Mammalia | Hist1h2bb 29 |
|
||
| H2bc3 16 |
|
||||
| Dog (Canis familiaris) |
Mammalia | LOC100855574 29 |
|
||
| Chimpanzee (Pan troglodytes) |
Mammalia | HIST1H2BB 29 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | LOC102549061 29 |
|
||
| Cow (Bos Taurus) |
Mammalia | LOC614206 29 |
|
- Species where no ortholog for H2BC3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for H2BC3 Gene
- ENSEMBL:
- Gene Tree for H2BC3 (if available)
- TreeFam:
- Gene Tree for H2BC3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2BC3: view image
- Alliance of Genome Resources:
- Additional Orthologs for H2BC3
Paralogs for H2BC3 Gene
Variants for H2BC3 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5926n100 | CNV | gain | 25217958 |
| esv3608392 | CNV | gain | 21293372 |
| nsv1023453 | CNV | gain | 25217958 |
| nsv1026692 | CNV | loss | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
| nsv509122 | CNV | insertion | 20534489 |
| nsv970081 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
45.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.52;
11.34% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2BC3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2BC3 Gene
Disorders for H2BC3 Gene
Additional Disease Information for H2BC3
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for H2BC3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for H2BC3 Gene
Publications for H2BC3 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R … Reinberg D (Cell 2006) 3 4
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (PMID: 16307923) Zhu B … Reinberg D (Molecular cell 2005) 3 4
- Inhibition of core histones acetylation by carcinogenic nickel(II). (PMID: 16283522) Golebiowski F … Kasprzak KS (Molecular and cellular biochemistry 2005) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for H2BC3 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H2BC3
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC3
- Origene Custom Protein Services for H2BC3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- OriGene qPCR primer pairs for H2BC3
- OriGene CRISPR knockouts for H2BC3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2BC3
- Sino Biological Human cDNA Clone for H2BC3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for H2BC3
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for H2BC3
- Novus Biologicals lysates for H2BC3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for H2BC3 (AFLGC-H2BC3)
- VectorBuilder Custom and pre-made DNA vectors for H2BC3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2BC3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2BC3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2BC3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2BC3
- Addgene plasmids for H2BC3
- antibodies-online: Show 9 available HIST1H2BB Antibodies ranked by validation data
- Compare Top HIST1H2BB Antibodies
- antibodies-online: Show 3 available HIST1H2BB Elisa Kits ranked by validation data
- Compare Top HIST1H2BB Elisa Kits
- Quality Products:
- antibodies-online: Show 4 available HIST1H2BB Proteins ranked by validation data
- Compare Top HIST1H2BB Proteins
- Horizon Cell Lines for H2BC3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Sources for H2BC3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
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