Free for academic non-profit institutions. Other users need a Commercial license
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with... See more...
Aliases for H2BC3 Gene
Aliases for H2BC3 Gene
External Ids for H2BC3 Gene
- HGNC: 4751
- Entrez Gene: 3018
- Ensembl: ENSG00000276410
- OMIM: 602803
- UniProtKB: P33778
Previous HGNC Symbols for H2BC3 Gene
- H2BFF
- HIST1H2BB
Summaries for H2BC3 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2BC3 Gene
H2BC3 (H2B Clustered Histone 3) is a Protein Coding gene. Among its related pathways are Chromatin organization and Signaling by GPCR. An important paralog of this gene is H2BC21.
UniProtKB/Swiss-Prot Summary for H2BC3 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Additional gene information for H2BC3 Gene
- HGNC(4751)
- Entrez Gene(3018)
- Ensembl(ENSG00000276410)
- OMIM(602803)
- UniProtKB(P33778)
- Open Targets Platform(ENSG00000276410)
- Search for H2BC3 at DataMed
- Search for H2BC3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2BC3 Gene
Genomics for H2BC3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2BC3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J026042 | Promoter/Enhancer | 2 | Ensembl ENCODE CraniofacialAtlas dbSUPER | 600.7 | -1.0 | -978 | 5 | SP1 HNRNPL CREB1 GATAD2A REST TFE3 SOX13 NFKBIZ POLR2A RCOR2 | H2AC5P H2BC3 H3C3 lnc-HIST1H3C-1 ENSG00000272462 ABT1 BTN2A2 HMGN4 BTN2A3P BTN3A2 | |
| GH06J026037 | Enhancer | 0.4 | Ensembl dbSUPER | 0.4 | +5.7 | 5712 | 0.8 | TRIM24 | ENSG00000272462 H2AC4 H2BC3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2BC3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2BC3
Genomic Locations for H2BC3 Gene
Genomic Locations for H2BC3 Gene
- chr6:26,043,227-26,043,713
- (GRCh38/hg38)
- Size:
- 487 bases
- Orientation:
- Minus strand
- chr6:26,043,455-26,043,885
- (GRCh37/hg19)
- Size:
- 431 bases
- Orientation:
- Minus strand
Genomic View for H2BC3 Gene
Genes around H2BC3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by HGNC
- 6p22.2 by Entrez Gene
- 6p22.2 by Ensembl
H2BC3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2BC3 Gene
Proteins for H2BC3 Gene
-
Protein details for H2BC3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P33778-H2B1B_HUMAN
- Recommended name:
- Histone H2B type 1-B
- Protein Accession:
- P33778
- Q4KN36
Protein attributes for H2BC3 Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13950 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2BC3 Gene
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes (By similarity).
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Glycosylation at Ser113
- NX_P33778 (NX_P33778-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2BC3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
-
OriGene Purified Proteins for H2BC3
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC3
- Origene Custom Protein Services for H2BC3
- Novus Biologicals lysates for H2BC3
-
Signalway Proteins for H2BC3
Assay Products
- G Biosciences Immunotag™ Human HIST1H2BB (Histone H2B type 1-B) ELISA
- antibodies-online: Show 3 available HIST1H2BB Elisa Kits ranked by validation data
- Compare Top HIST1H2BB Elisa Kits
-
Quality Products:
-
Boster Bio ELISA Kits for H2BC3
No data available for DME Specific Peptides for H2BC3 Gene
Domains & Families for H2BC3 Gene
Gene Families for H2BC3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for H2BC3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for H2BC3 Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H2B.f (H2B1B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P33778- Family:
-
- Belongs to the histone H2B family.
Function for H2BC3 Gene
Molecular function for H2BC3 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phenotypes From GWAS Catalog for H2BC3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA,NAS | 9439656 |
| GO:0005515 | protein binding | IPI | 22720776 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2BC3 Gene
- GenomeRNAi human phenotypes for H2BC3:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased Nanog expression
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Increased Sindbis virus (SINV) infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC3 - Select products 50% OFF >
- * H2BC3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2BC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
miRNA for H2BC3 Gene
- miRTarBase miRNAs that target H2BC3
-
- hsa-miR-34a-5p (MIRT025273)
- hsa-miR-652-3p (MIRT039494)
- hsa-miR-196a-5p (MIRT048188)
- hsa-miR-760 (MIRT360243)
- hsa-miR-6822-3p (MIRT360247)
- hsa-miR-5693 (MIRT511736)
- hsa-miR-6839-3p (MIRT511737)
- hsa-miR-4507 (MIRT511738)
- hsa-miR-3940-5p (MIRT511739)
- hsa-miR-8057 (MIRT511740)
- hsa-miR-6079 (MIRT511741)
- hsa-miR-629-5p (MIRT511742)
- hsa-miR-4766-5p (MIRT511743)
- hsa-miR-146a-3p (MIRT511744)
- hsa-miR-1276 (MIRT511745)
- hsa-miR-6802-5p (MIRT523237)
- hsa-miR-6865-5p (MIRT523238)
- hsa-miR-6815-5p (MIRT523239)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Clone Products
- Applied Biological Materials (abm): Clones for H2BC3 - Select products 50% OFF >
- * H2BC3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2BC3
- Addgene plasmids for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
Cell Line Products
-
Horizon Cell Lines for H2BC3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2BC3 Gene
Localization for H2BC3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2BC3 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000784 | nuclear chromosome, telomeric region | HDA | 19135898 |
| GO:0000786 | nucleosome | NAS | 9439656 |
| GO:0005634 | nucleus | IEA,IDA | 16319397 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for H2BC3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.35
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence (REACTOME) | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for H2BC3 Gene
68 Reactome pathways for H2BC3 Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for H2BC3 Gene
1 GeneGo (Thomson Reuters) pathway for H2BC3 Gene
- Signal transduction Activin A signaling regulation
2 Cell Signaling Technology pathways for H2BC3 Gene
Interacting Proteins for H2BC3 Gene
Selected Interacting proteins:
P33778-H2B1B_HUMAN
ENSP00000482674
for H2BC3 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for H2BC3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006334 | nucleosome assembly | IBA,NAS | 9439656 |
| GO:0016567 | protein ubiquitination | TAS | -- |
Transcripts for H2BC3 Gene
mRNA/cDNA for H2BC3 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000615966 487 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC3 - Select products 50% OFF >
- * H2BC3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2BC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Clone Products
- Applied Biological Materials (abm): Clones for H2BC3 - Select products 50% OFF >
- * H2BC3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2BC3
- Addgene plasmids for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
Relevant External Links for H2BC3 Gene
- GeneLoc Exon Structure for
- H2BC3
Expression for H2BC3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Choroid Plexus Progenitor Cells Choroid Plexus
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2BC3
SOURCE GeneReport for Unigene cluster for H2BC3 Gene:
Hs.553494Primer Products
-
OriGene qPCR primer pairs for H2BC3
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2BC3 Gene
Orthologs for H2BC3 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Mouse (Mus musculus) |
Mammalia | Hist1h2bb 30 |
|
||
| H2bc3 17 |
|
||||
| Dog (Canis familiaris) |
Mammalia | LOC100855574 30 |
|
||
| Chimpanzee (Pan troglodytes) |
Mammalia | HIST1H2BB 30 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | LOC102549061 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | LOC614206 30 |
|
- Species where no ortholog for H2BC3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for H2BC3 Gene
- ENSEMBL:
- Gene Tree for H2BC3 (if available)
- TreeFam:
- Gene Tree for H2BC3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2BC3: view image
Paralogs for H2BC3 Gene
Variants for H2BC3 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5926n100 | CNV | gain | 25217958 |
| esv3608392 | CNV | gain | 21293372 |
| nsv1023453 | CNV | gain | 25217958 |
| nsv1026692 | CNV | loss | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
| nsv509122 | CNV | insertion | 20534489 |
| nsv970081 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
45.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.52;
11.34% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2BC3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- H2BC3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2BC3 Gene
Disorders for H2BC3 Gene
Additional Disease Information for H2BC3
No disorders were found for H2BC3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for H2BC3 Gene
Publications for H2BC3 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R … Reinberg D (Cell 2006) 3 4
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (PMID: 16307923) Zhu B … Reinberg D (Molecular cell 2005) 3 4
- Inhibition of core histones acetylation by carcinogenic nickel(II). (PMID: 16283522) Golebiowski F … Kasprzak KS (Molecular and cellular biochemistry 2005) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for H2BC3 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H2BC3
- Search Origene for MassSpec and Protein Over-expression Lysates for H2BC3
- Origene Custom Protein Services for H2BC3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2BC3
- Browse OriGene Inhibitory RNA Products For H2BC3
- OriGene qPCR primer pairs for H2BC3
- OriGene CRISPR knockouts for H2BC3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2BC3
- Sino Biological Human cDNA Clone for H2BC3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for H2BC3
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for H2BC3
- Novus Biologicals lysates for H2BC3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder Custom and pre-made DNA vectors for H2BC3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2BC3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2BC3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2BC3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2BC3
- Addgene plasmids for H2BC3
- antibodies-online: Show 9 available HIST1H2BB Antibodies ranked by validation data
- Compare Top HIST1H2BB Antibodies
- antibodies-online: Show 3 available HIST1H2BB Elisa Kits ranked by validation data
- Compare Top HIST1H2BB Elisa Kits
- Quality Products:
- antibodies-online: Show 4 available HIST1H2BB Proteins ranked by validation data
- Compare Top HIST1H2BB Proteins
- Horizon Cell Lines for H2BC3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2BC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2BC3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2BC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2BC3
Sources for H2BC3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB