Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in ... See more...
Aliases for H2BC20P Gene
Aliases for H2BC20P Gene
External Ids for H2BC20P Gene
- HGNC: 20516
- Entrez Gene: 337873
- Ensembl: ENSG00000261716
Previous HGNC Symbols for H2BC20P Gene
- HIST2H2BC
Summaries for H2BC20P Gene
-
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is found in a histone cluster on chromosome 1. [provided by RefSeq, Oct 2015]
GeneCards Summary for H2BC20P Gene
H2BC20P (H2B Clustered Histone 20, Pseudogene) is a Pseudogene.
Additional gene information for H2BC20P Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2BC20P Gene
Genomics for H2BC20P Gene
GeneHancer (GH) Regulatory Elements for H2BC20P Gene
Promoters and enhancers for H2BC20P Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2BC20P on UCSC Golden Path with GeneCards custom track
Genomic Locations for H2BC20P Gene
Genomic Locations for H2BC20P Gene
- chr1:149,844,498-149,850,937
- (GRCh38/hg38)
- Size:
- 6,440 bases
- Orientation:
- Minus strand
- chr1:149,816,065-149,820,591
- (GRCh37/hg19)
- Size:
- 4,527 bases
- Orientation:
- Minus strand
Genomic View for H2BC20P Gene
Genes around H2BC20P on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q21.2 by HGNC
- 1q21.2 by Entrez Gene
- 1q21.2 by Ensembl
H2BC20P Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2BC20P Gene
Proteins for H2BC20P Gene
Post-translational modifications for H2BC20P Gene
No Post-translational modifications
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for H2BC20P
- Origene Custom Protein Services for H2BC20P
No data available for DME Specific Peptides for H2BC20P Gene
Domains & Families for H2BC20P Gene
Gene Families for H2BC20P Gene
- HGNC:
Suggested Antigen Peptide Sequences for H2BC20P Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H2B.t (H2B2C_HUMAN)
No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for H2BC20P Gene
Function for H2BC20P Gene
Phenotypes From GWAS Catalog for H2BC20P Gene
Phenotypes for H2BC20P Gene
- GenomeRNAi human phenotypes for H2BC20P:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC20P - Select products 50% OFF >
- * H2BC20P CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * H2BC20P CRISPR applications: KO, Activation, Repression, and more - Browse All
- Browse CRISPR knockouts for H2BC20P
- genomics-online: gRNA clones - Search results for available HIST2H2BC gene related products
miRNA Products
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available HIST2H2BC gene related products
Clone Products
- Applied Biological Materials (abm): Clones for H2BC20P - Select products 50% OFF >
- * H2BC20P as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * H2BC20P tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- genomics-online: cdna clones - Search results for available HIST2H2BC gene related products
- orf clones - Search results for available HIST2H2BC gene related products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for H2BC20P Gene
Localization for H2BC20P Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for H2BC20P Gene
Transcripts for H2BC20P Gene
mRNA/cDNA for H2BC20P Gene
- (2) Additional mRNA sequences :
- (11) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000564237 6440 bps (ENST00000564237.2)
- ENST00000498492 580 bps (ENST00000498492.2)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2BC20P - Select products 50% OFF >
- * H2BC20P CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * H2BC20P CRISPR applications: KO, Activation, Repression, and more - Browse All
- Browse CRISPR knockouts for H2BC20P
- genomics-online: gRNA clones - Search results for available HIST2H2BC gene related products
miRNA Products
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available HIST2H2BC gene related products
Clone Products
- Applied Biological Materials (abm): Clones for H2BC20P - Select products 50% OFF >
- * H2BC20P as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * H2BC20P tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- genomics-online: cdna clones - Search results for available HIST2H2BC gene related products
- orf clones - Search results for available HIST2H2BC gene related products
Expression for H2BC20P Gene
NURSA nuclear receptor signaling pathways regulating expression of H2BC20P Gene:
H2BC20PSOURCE GeneReport for Unigene cluster for H2BC20P Gene:
Hs.666643
No Expression Related Data Available
Primer Products
- genomics-online: primer clones - Search results for available HIST2H2BC gene related products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2BC20P Gene
Orthologs for H2BC20P Gene
No data available for Orthologs for H2BC20P Gene
Paralogs for H2BC20P Gene
No data available for Paralogs for H2BC20P Gene
Variants for H2BC20P Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1009565784 | -- | 149,849,706(-) | T/G | downstream_transcript_variant | |
| rs1013070338 | -- | 149,850,237(-) | T/C | non_coding_transcript_variant | |
| rs1013085481 | -- | 149,850,002(-) | T/C | downstream_transcript_variant | |
| rs1015153667 | -- | 149,849,708(-) | G/C | downstream_transcript_variant | |
| rs1024496342 | -- | 149,850,255(-) | C/A | non_coding_transcript_variant |
Additional Variant Information for H2BC20P Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- H2BC20P
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for H2BC20P Gene
Disorders for H2BC20P Gene
No disorders were found for H2BC20P Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for H2BC20P Gene
Publications for H2BC20P Gene
- Functional characterization of a human histone gene cluster duplication. (PMID: 15527963) Braastad CD … Stein GS (Gene 2004) 2 3 56
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 56
- Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. (PMID: 27634302) Oliviero G … Cagney G (Molecular & cellular proteomics : MCP 2016) 3 56
- Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R … Boisvert FM (Molecular & cellular proteomics : MCP 2015) 3 56
- Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line. (PMID: 20194426) González-Romero R … Eirín-López JM (Molecular biology and evolution 2010) 3 56
ExternalLinks
Products for H2BC20P Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for H2BC20P
- Origene Custom Protein Services for H2BC20P
- Browse OriGene Inhibitory RNA Products For H2BC20P
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for H2BC20P
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2BC20P
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Invitrogen Antibodies for H2BC20P (AFLGC-HIST2H2BC)
- antibodies-online: Search results for available HIST2H2BC related products ranked by validation data
- antibodies-online: Search results for available HIST2H2BC related products ranked by validation data
- antibodies-online: Search results for available HIST2H2BC related products ranked by validation data
- genomics-online: cdna clones - Search results for available HIST2H2BC gene related products
- orf clones - Search results for available HIST2H2BC gene related products
- genomics-online: gRNA clones - Search results for available HIST2H2BC gene related products
- genomics-online: primer clones - Search results for available HIST2H2BC gene related products
- genomics-online: shRNA clones - Search results for available HIST2H2BC gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for H2BC20P
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for H2BC20P
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2BC20P
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for H2BC20P
Sources for H2BC20P Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
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- (172) Modomics
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- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource