Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in ... See more...

Aliases for H2BC19P Gene

Aliases for H2BC19P Gene

  • H2B Clustered Histone 19, Pseudogene 2 3
  • Histone Cluster 2 H2B Family Member D (Pseudogene) 2 3
  • Histone Cluster 2, H2bd (Pseudogene) 2 3
  • H2B Histone Family, Member O 2 3
  • Histone 2, H2bd 2 3
  • HIST2H2BD 3
  • H2B/O 3
  • H2B/S 3
  • H2BFO 3

External Ids for H2BC19P Gene

Previous HGNC Symbols for H2BC19P Gene

  • H2BFO
  • HIST2H2BD

Summaries for H2BC19P Gene

Entrez Gene Summary for H2BC19P Gene

  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is found in a histone cluster on chromosome 1. [provided by RefSeq, Oct 2015]

GeneCards Summary for H2BC19P Gene

H2BC19P (H2B Clustered Histone 19, Pseudogene) is a Pseudogene.

Additional gene information for H2BC19P Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2BC19P Gene

Genomics for H2BC19P Gene

GeneHancer (GH) Regulatory Elements for H2BC19P Gene

Promoters and enhancers for H2BC19P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J149840 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 750.6 -0.9 -938 8.6 POLR2A HLF SP1 MLLT1 CEBPG CREB1 CEBPA ZBTB33 CEBPB CHD2 H2AC18 ENSG00000220323 H2BC19P H3C14 lnc-HIST2H4A-1 piR-45268-001 SV2A H2AC20 H2BC21 BOLA1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around H2BC19P on UCSC Golden Path with GeneCards custom track

Genomic Locations for H2BC19P Gene

Genomic Locations for H2BC19P Gene
chr1:149,843,039-149,843,510
(GRCh38/hg38)
Size:
472 bases
Orientation:
Plus strand

Genomic View for H2BC19P Gene

Genes around H2BC19P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
H2BC19P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for H2BC19P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for H2BC19P Gene

Proteins for H2BC19P Gene

Post-translational modifications for H2BC19P Gene

No Post-translational modifications

No data available for DME Specific Peptides for H2BC19P Gene

Domains & Families for H2BC19P Gene

Gene Families for H2BC19P Gene

HGNC:

Suggested Antigen Peptide Sequences for H2BC19P Gene

GenScript: Design optimal peptide antigens:
  • Putative histone H2B type 2-D (H2B2D_HUMAN)
genes like me logo Genes that share domains with H2BC19P: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for H2BC19P Gene

Function for H2BC19P Gene

Phenotypes From GWAS Catalog for H2BC19P Gene

Gene Ontology (GO) - Molecular Function for H2BC19P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IBA 21873635
GO:0046982 protein heterodimerization activity IEA --
genes like me logo Genes that share ontologies with H2BC19P: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for H2BC19P Gene

Localization for H2BC19P Gene

Gene Ontology (GO) - Cellular Components for H2BC19P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000786 nucleosome IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with H2BC19P: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for H2BC19P Gene

Pathways & Interactions for H2BC19P Gene

PathCards logo

SuperPathways for H2BC19P Gene

No Data Available

Gene Ontology (GO) - Biological Process for H2BC19P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IBA 21873635
genes like me logo Genes that share ontologies with H2BC19P: view

No data available for Pathways by source and SIGNOR curated interactions for H2BC19P Gene

Drugs & Compounds for H2BC19P Gene

No Compound Related Data Available

Transcripts for H2BC19P Gene

mRNA/cDNA for H2BC19P Gene

(1) Additional mRNA sequences :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for H2BC19P Gene

No ASD Table

Relevant External Links for H2BC19P Gene

GeneLoc Exon Structure for
H2BC19P
ECgene alternative splicing isoforms for
H2BC19P

Expression for H2BC19P Gene

NURSA nuclear receptor signaling pathways regulating expression of H2BC19P Gene:

H2BC19P
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2BC19P Gene

Orthologs for H2BC19P Gene

No data available for Orthologs and Evolution for H2BC19P Gene

Paralogs for H2BC19P Gene

No data available for Paralogs for H2BC19P Gene

Variants for H2BC19P Gene

Additional Variant Information for H2BC19P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
H2BC19P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for H2BC19P Gene

Disorders for H2BC19P Gene

No disorders were found for H2BC19P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for H2BC19P Gene

Publications for H2BC19P Gene

  1. Functional characterization of a human histone gene cluster duplication. (PMID: 15527963) Braastad CD … Stein GS (Gene 2004) 2 3 56
  2. The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 56
  3. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R … Boisvert FM (Molecular & cellular proteomics : MCP 2015) 3 56
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 56
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 56

Products for H2BC19P Gene

Sources for H2BC19P Gene