Free for academic non-profit institutions. Other users need a Commercial license
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and ... See more...
Aliases for H2AC14 Gene
Aliases for H2AC14 Gene
External Ids for H2AC14 Gene
- HGNC: 4727
- Entrez Gene: 8331
- Ensembl: ENSG00000276368
- OMIM: 602791
- UniProtKB: Q99878
Previous HGNC Symbols for H2AC14 Gene
- H2AFE
- HIST1H2AJ
Summaries for H2AC14 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2AC14 Gene
H2AC14 (H2A Clustered Histone 14) is a Protein Coding gene. Diseases associated with H2AC14 include Riddle Syndrome. Among its related pathways are Chromatin organization and Signaling by GPCR. An important paralog of this gene is H2AC11.
UniProtKB/Swiss-Prot Summary for H2AC14 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Additional gene information for H2AC14 Gene
- HGNC(4727)
- Entrez Gene(8331)
- Ensembl(ENSG00000276368)
- OMIM(602791)
- UniProtKB(Q99878)
- Open Targets Platform(ENSG00000276368)
- Search for H2AC14 at DataMed
- Search for H2AC14 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2AC14 Gene
Genomics for H2AC14 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2AC14 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J027834 | Promoter/Enhancer | 2.7 | EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER | 7.7 | -22.7 | -22664 | 6.7 | ZNF221 SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 ZNF629 REST TFE3 | H2BC15 H2AC15 ZSCAN12 ZKSCAN8 ZKSCAN3 ZSCAN9 ZSCAN26 ZKSCAN4 PGBD1 GUSBP2 | |
| GH06J027887 | Promoter/Enhancer | 2.3 | FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER | 4 | -78.7 | -78704 | 11.9 | RNF2 ARHGAP35 CEBPG SP1 HNRNPL CREB1 GATAD2A CTCF ATF7 TEAD4 | H2BC17 H2AC17 H3C12 piR-39028 piR-38252 piR-51953-002 piR-56252 ZKSCAN8 ZKSCAN4 ZSCAN9 | |
| GH06J027805 | Promoter/Enhancer | 2.3 | FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER | 3 | +2.7 | 2662 | 12.7 | ARHGAP35 CEBPG SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 REST ZNF629 | Z46261-004 piR-57462 ZKSCAN4 ZSCAN9 ZKSCAN8 ZKSCAN3 ZSCAN12 ZNF603P ZSCAN26 GUSBP2 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2AC14 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2AC14
Genomic Locations for H2AC14 Gene
Genomic Locations for H2AC14 Gene
- chr6:27,814,302-27,814,777
- (GRCh38/hg38)
- Size:
- 476 bases
- Orientation:
- Minus strand
- chr6:27,782,080-27,782,607
- (GRCh37/hg19)
- Size:
- 528 bases
- Orientation:
- Minus strand
Genomic View for H2AC14 Gene
Genes around H2AC14 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by HGNC
- 6p22.1 by Entrez Gene
- 6p22.1 by Ensembl
H2AC14 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2AC14 Gene
Proteins for H2AC14 Gene
-
Protein details for H2AC14 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99878-H2A1J_HUMAN
- Recommended name:
- Histone H2A type 1-J
- Protein Accession:
- Q99878
- A2RUU6
- Q5JXQ5
Protein attributes for H2AC14 Gene
- Size:
- 128 amino acids
- Molecular mass:
- 13936 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2AC14 Gene
- Deiminated on Arg-4 in granulocytes upon calcium entry.
- Monoubiquitination of Lys-120 (H2AK119Ub) by RING1, TRIM37 and RNF2/RING2 complex gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It is involved in the initiation of both imprinted and random X inactivation. Ubiquitinated H2A is enriched in inactive X chromosome chromatin. Ubiquitination of H2A functions downstream of methylation of 'Lys-27' of histone H3 (H3K27me). H2AK119Ub by RNF2/RING2 can also be induced by ultraviolet and may be involved in DNA repair. Monoubiquitination of Lys-120 (H2AK119Ub) by TRIM37 may promote transformation of cells in a number of breast cancers (PubMed:25470042). Following DNA double-strand breaks (DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties by the E2 ligase UBE2N and the E3 ligases RNF8 and RNF168, leading to the recruitment of repair proteins to sites of DNA damage. Ubiquitination at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) in response to DNA damage is initiated by RNF168 that mediates monoubiquitination at these 2 sites, and 'Lys-63'-linked ubiquitin are then conjugated to monoubiquitin; RNF8 is able to extend 'Lys-63'-linked ubiquitin chains in vitro. Deubiquitinated by USP51 at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) after damaged DNA is repaired (PubMed:27083998). H2AK119Ub and ionizing radiation-induced 'Lys-63'-linked ubiquitination (H2AK13Ub and H2AK15Ub) are distinct events.
- Phosphorylation on Ser-2 (H2AS1ph) is enhanced during mitosis. Phosphorylation on Ser-2 by RPS6KA5/MSK1 directly represses transcription. Acetylation of H3 inhibits Ser-2 phosphorylation by RPS6KA5/MSK1. Phosphorylation at Thr-121 (H2AT120ph) by DCAF1 is present in the regulatory region of many tumor suppresor genes and down-regulates their transcription.
- Glutamine methylation at Gln-105 (H2AQ104me) by FBL is specifically dedicated to polymerase I. It is present at 35S ribosomal DNA locus and impairs binding of the FACT complex (PubMed:24352239).
- Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage.
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Ubiquitination at Lys16
- NX_Q99878 (NX_Q99878-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2AC14 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Invitrogen Antibodies for H2AC14 (AFLGC-H2AC14)
- antibodies-online: Show 3 available HIST1H2AJ Antibodies ranked by validation data
- Compare Top HIST1H2AJ Antibodies
-
Recommended
Protein Products
-
OriGene Purified Proteins for H2AC14
- Search Origene for MassSpec and Protein Over-expression Lysates for H2AC14
- Origene Custom Protein Services for H2AC14
No data available for DME Specific Peptides for H2AC14 Gene
Domains & Families for H2AC14 Gene
Gene Families for H2AC14 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for H2AC14 Gene
- InterPro:
- Blocks:
-
- Histone H2A
- ProtoNet:
Suggested Antigen Peptide Sequences for H2AC14 Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H2A/e (H2A1J_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q99878- Family:
-
- Belongs to the histone H2A family.
Function for H2AC14 Gene
Molecular function for H2AC14 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phenotypes From GWAS Catalog for H2AC14 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0003677 | DNA binding | IBA | -- |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2AC14 Gene
- GenomeRNAi human phenotypes for H2AC14:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2AC14 - Select products 50% OFF >
- * H2AC14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2AC14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC14
miRNA for H2AC14 Gene
- miRTarBase miRNAs that target H2AC14
-
- hsa-miR-34a-5p (MIRT025519)
- hsa-miR-92b-5p (MIRT037794)
- hsa-miR-193b-3p (MIRT041250)
- hsa-miR-324-3p (MIRT042930)
- hsa-miR-16-5p (MIRT051259)
- hsa-miR-760 (MIRT360351)
- hsa-miR-6822-3p (MIRT360355)
- hsa-miR-5693 (MIRT511757)
- hsa-miR-8057 (MIRT511758)
- hsa-miR-573 (MIRT511759)
- hsa-miR-3616-5p (MIRT511760)
- hsa-miR-4795-5p (MIRT511761)
- hsa-miR-4766-5p (MIRT511762)
- hsa-miR-146a-3p (MIRT511763)
- hsa-miR-1276 (MIRT511764)
- hsa-miR-491-3p (MIRT523240)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC14
- Browse OriGene Inhibitory RNA Products For H2AC14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC14
Clone Products
- Applied Biological Materials (abm): Clones for H2AC14 - Select products 50% OFF >
- * H2AC14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2AC14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC14
Cell Line Products
-
Horizon Cell Lines for H2AC14
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2AC14 Gene
Localization for H2AC14 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2AC14 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 4 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | IEA | -- |
| GO:0000790 | nuclear chromatin | IBA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for H2AC14 Gene
Pathways & Interactions for H2AC14 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.35
|
| 2 | Cellular Senescence (REACTOME) | ||
| 3 | Chromosome Maintenance | ||
| 4 | Cell Cycle, Mitotic |
.83
|
.60
|
| 5 | Chromatin organization | ||
Pathways by source for H2AC14 Gene
58 Reactome pathways for H2AC14 Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for H2AC14 Gene
1 GeneGo (Thomson Reuters) pathway for H2AC14 Gene
- Signal transduction Activin A signaling regulation
Interacting Proteins for H2AC14 Gene
GPS-Prot Interaction Network for H2AC14
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | IBA | -- |
| GO:0006342 | chromatin silencing | IBA | -- |
| GO:0008150 | biological_process | ND | -- |
No data available for SIGNOR curated interactions for H2AC14 Gene
Drugs & Compounds for H2AC14 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6556 |
Transcripts for H2AC14 Gene
mRNA/cDNA for H2AC14 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000333151 476 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2AC14 - Select products 50% OFF >
- * H2AC14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2AC14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC14
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC14
- Browse OriGene Inhibitory RNA Products For H2AC14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC14
Clone Products
- Applied Biological Materials (abm): Clones for H2AC14 - Select products 50% OFF >
- * H2AC14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2AC14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC14
Relevant External Links for H2AC14 Gene
- GeneLoc Exon Structure for
- H2AC14
Expression for H2AC14 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2AC14
SOURCE GeneReport for Unigene cluster for H2AC14 Gene:
Hs.406691
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for H2AC14
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2AC14 Gene
Orthologs for H2AC14 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC737087 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | HIST1H2AJ 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | LOC488304 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Hist1h2af 30 |
|
||
| H2ac10 17 |
|
- Species where no ortholog for H2AC14 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for H2AC14 Gene
- ENSEMBL:
- Gene Tree for H2AC14 (if available)
- TreeFam:
- Gene Tree for H2AC14 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2AC14: view image
Paralogs for H2AC14 Gene
Paralogs for H2AC14 Gene
Pseudogenes.org Pseudogenes for H2AC14 Gene
Variants for H2AC14 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3890803 | CNV | loss | 25118596 |
| nsv1017057 | CNV | gain | 25217958 |
| nsv830618 | CNV | gain | 17160897 |
| nsv970094 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
39.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.19;
4.26% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2AC14 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- H2AC14
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2AC14 Gene
Disorders for H2AC14 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| riddle syndrome |
|
|
Search H2AC14 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for H2AC14
No data available for UniProtKB/Swiss-Prot and Genatlas for H2AC14 Gene
Publications for H2AC14 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- The human histone gene cluster at the D6S105 locus. (PMID: 9439656) Albig W … Doenecke D (Human genetics 1997) 2 3 4
- Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics. (PMID: 31542297) Bao X … Li XD (Molecular cell 2019) 4
- WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks. (PMID: 31048545) Caron P … van Attikum H (Genes & development 2019) 3
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
ExternalLinks
Products for H2AC14 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H2AC14
- Search Origene for MassSpec and Protein Over-expression Lysates for H2AC14
- Origene Custom Protein Services for H2AC14
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC14
- Browse OriGene Inhibitory RNA Products For H2AC14
- OriGene qPCR primer pairs for H2AC14
- OriGene CRISPR knockouts for H2AC14
- OriGene ORF clones in human for H2AC14
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2AC14
- Sino Biological Human cDNA Clone for H2AC14
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Invitrogen Antibodies for H2AC14 (AFLGC-H2AC14)
- VectorBuilder Custom and pre-made DNA vectors for H2AC14 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2AC14 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2AC14 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2AC14 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2AC14
- antibodies-online: Show 3 available HIST1H2AJ Antibodies ranked by validation data
- Compare Top HIST1H2AJ Antibodies
- Recommended
- antibodies-online: Search results for available HIST1H2AJ related products ranked by validation data
- antibodies-online: Show 4 available HIST1H2AJ Proteins ranked by validation data
- Compare Top HIST1H2AJ Proteins
- Horizon Cell Lines for H2AC14
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC14
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2AC14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC14
Sources for H2AC14 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB