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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and ... See more...
Aliases for H2AC11 Gene
Aliases for H2AC11 Gene
External Ids for H2AC11 Gene
- HGNC: 4737
- NCBI Entrez Gene: 8969
- Ensembl: ENSG00000196787
- OMIM®: 615012
- UniProtKB/Swiss-Prot: P0C0S8
Previous HGNC Symbols for H2AC11 Gene
- H2AFP
- HIST1H2AG
Previous GeneCards Identifiers for H2AC11 Gene
- GC06P027645
- GC06P028371
- GC06P028875
- GC06P049175
Summaries for H2AC11 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2AC11 Gene
H2AC11 (H2A Clustered Histone 11) is a Protein Coding gene. Diseases associated with H2AC11 include Riddle Syndrome. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Chromatin organization. An important paralog of this gene is H2AC13.
UniProtKB/Swiss-Prot Summary for H2AC11 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Additional gene information for H2AC11 Gene
- HGNC (4737)
- NCBI Entrez Gene (8969)
- Ensembl (ENSG00000196787)
- OMIM® (615012)
- UniProtKB/Swiss-Prot (P0C0S8)
- Open Targets Platform(ENSG00000196787)
- Alliance of Genome Resources
- Search for H2AC11 at DataMed
- Search for H2AC11 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2AC11 Gene
Genomics for H2AC11 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2AC11 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J027126 | Promoter/Enhancer | 2.5 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 0.7 | +5.0 | 4980 | 23 | BCLAF1 SP1 ZNF207 NCOR1 MYC IKZF1 ZNF654 ZNF600 SSRP1 JUND | H4C9 HSALNG0048838 H2BC11 ABT1 HMGN4 BTN2A2 ZNF322 BTN2A1 ENSG00000261584 BTN2A3P |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2AC11 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2AC11
Genomic Locations for H2AC11 Gene
Latest Assembly
- chr6:27,133,042-27,135,291
- (GRCh38/hg38)
- Size:
- 2,250 bases
- Orientation:
- Plus strand
Previous Assembly
- chr6:27,100,822-27,101,314
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 493 bases
- Orientation:
- Plus strand
Genomic View for H2AC11 Gene
Genes around H2AC11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by HGNC
- 6p22.1 by Entrez Gene
- 6p22.1 by Ensembl
H2AC11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2AC11 Gene
Proteins for H2AC11 Gene
-
Protein details for H2AC11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0C0S8-H2A1_HUMAN
- Recommended name:
- Histone H2A type 1
- Protein Accession:
- P0C0S8
- P02261
- Q2M1R2
- Q76PA6
Protein attributes for H2AC11 Gene
- Size:
- 130 amino acids
- Molecular mass:
- 14091 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2AC11 Gene
- Deiminated on Arg-4 in granulocytes upon calcium entry.
- Monoubiquitination of Lys-120 (H2AK119Ub) by RING1, TRIM37 and RNF2/RING2 complex gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It is involved in the initiation of both imprinted and random X inactivation. Ubiquitinated H2A is enriched in inactive X chromosome chromatin. Ubiquitination of H2A functions downstream of methylation of 'Lys-27' of histone H3 (H3K27me). H2AK119Ub by RNF2/RING2 can also be induced by ultraviolet and may be involved in DNA repair. Monoubiquitination of Lys-120 (H2AK119Ub) by TRIM37 may promote transformation of cells in a number of breast cancers (PubMed:25470042). Following DNA double-strand breaks (DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties by the E2 ligase UBE2N and the E3 ligases RNF8 and RNF168, leading to the recruitment of repair proteins to sites of DNA damage. Ubiquitination at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) in response to DNA damage is initiated by RNF168 that mediates monoubiquitination at these 2 sites, and 'Lys-63'-linked ubiquitin are then conjugated to monoubiquitin; RNF8 is able to extend 'Lys-63'-linked ubiquitin chains in vitro. Deubiquitinated by USP51 at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) after damaged DNA is repaired (PubMed:27083998). H2AK119Ub and ionizing radiation-induced 'Lys-63'-linked ubiquitination (H2AK13Ub and H2AK15Ub) are distinct events.
- Phosphorylation on Ser-2 (H2AS1ph) is enhanced during mitosis. Phosphorylation on Ser-2 by RPS6KA5/MSK1 directly represses transcription. Acetylation of H3 inhibits Ser-2 phosphorylation by RPS6KA5/MSK1. Phosphorylation at Thr-121 (H2AT120ph) by DCAF1 is present in the regulatory region of many tumor suppresor genes and down-regulates their transcription.
- Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage.
- Glutamine methylation at Gln-105 (H2AQ104me) by FBL is specifically dedicated to polymerase I. It is present at 35S ribosomal DNA locus and impairs binding of the FACT complex (PubMed:24352239).
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Ubiquitination at Lys16
- NX_P0C0S8 (NX_P0C0S8-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2AC11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for H2AC11
- Invitrogen Antibodies for H2AC11 (AFLGC-H2AC11)
-
Custom Antibody ServicesProSci Antibodies for H2AC11
Protein products for research
-
OriGene Purified Proteins for H2AC11
- Search Origene for MassSpec and Protein Over-expression Lysates for H2AC11
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- Novus Biologicals lysates for H2AC11
- antibodies-online: Show 9 available HIST1H2AG Proteins ranked by validation data
- Compare Top HIST1H2AG Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for H2AC11 Gene
Domains & Families for H2AC11 Gene
Gene Families for H2AC11 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for H2AC11 Gene
- InterPro:
- Blocks:
-
- Histone H2A
Graphical View of Domain Structure for InterPro Entry
P0C0S8- Family:
-
- Belongs to the histone H2A family.
No data available for Suggested Antigen Peptide Sequences for H2AC11 Gene
Function for H2AC11 Gene
Molecular function for H2AC11 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phenotypes From GWAS Catalog for H2AC11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 15161933 |
| GO:0019899 | enzyme binding | IPI | 17980597 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2AC11 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
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- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H2AC11
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miRNA for H2AC11 Gene
- miRTarBase miRNAs that target H2AC11
-
- hsa-miR-34a-5p (MIRT025441)
- hsa-miR-98-5p (MIRT027642)
- hsa-miR-1276 (MIRT317297)
- hsa-miR-4529-3p (MIRT317300)
- hsa-miR-4520-2-3p (MIRT317302)
- hsa-miR-7850-5p (MIRT317303)
- hsa-miR-345-3p (MIRT367324)
- hsa-miR-1291 (MIRT367325)
- hsa-miR-6775-3p (MIRT367326)
- hsa-miR-7976 (MIRT367327)
- hsa-miR-29b-2-5p (MIRT509313)
- hsa-miR-328-3p (MIRT509314)
- hsa-miR-8058 (MIRT509315)
- hsa-miR-5009-5p (MIRT509316)
- hsa-miR-1269b (MIRT509317)
- hsa-miR-1269a (MIRT509318)
- hsa-miR-6748-5p (MIRT509319)
- hsa-miR-663b (MIRT509320)
- hsa-miR-5087 (MIRT509321)
- hsa-miR-4483 (MIRT509322)
- hsa-miR-1293 (MIRT509323)
- hsa-miR-6766-5p (MIRT509324)
- hsa-miR-6756-5p (MIRT509325)
- hsa-miR-6745 (MIRT509326)
- hsa-miR-363-5p (MIRT509327)
- hsa-miR-6851-3p (MIRT509328)
- hsa-miR-7703 (MIRT693455)
- hsa-miR-6512-3p (MIRT693456)
- hsa-miR-6720-5p (MIRT693457)
- hsa-miR-4252 (MIRT693458)
- hsa-miR-661 (MIRT693459)
- hsa-miR-4793-3p (MIRT693460)
- hsa-miR-6849-3p (MIRT693461)
- hsa-miR-766-3p (MIRT693462)
- hsa-miR-1273g-3p (MIRT693463)
- hsa-miR-508-5p (MIRT693464)
- hsa-miR-1247-3p (MIRT736382)
- hsa-miR-1827 (MIRT738109)
- hsa-miR-25-5p (MIRT739378)
- hsa-miR-3664-3p (MIRT742023)
- hsa-miR-3929 (MIRT743069)
- hsa-miR-4327 (MIRT744099)
- hsa-miR-4419b (MIRT744236)
- hsa-miR-4433a-3p (MIRT744353)
- hsa-miR-4459 (MIRT744801)
- hsa-miR-4478 (MIRT745075)
- hsa-miR-4649-3p (MIRT746480)
- hsa-miR-4695-5p (MIRT747178)
- hsa-miR-4722-5p (MIRT747596)
- hsa-miR-4768-3p (MIRT748620)
- hsa-miR-485-5p (MIRT749064)
- hsa-miR-510-5p (MIRT749729)
- hsa-miR-512-5p (MIRT749755)
- hsa-miR-5690 (MIRT751204)
- hsa-miR-6087 (MIRT751906)
- hsa-miR-665 (MIRT753632)
- hsa-miR-6808-5p (MIRT756567)
- hsa-miR-6884-5p (MIRT758506)
- hsa-miR-6893-5p (MIRT758711)
- hsa-miR-7160-5p (MIRT759317)
- hsa-miR-940 (MIRT760808)
- hsa-miR-4537 (MIRT770161)
- hsa-miR-455-3p (MIRT770337)
- hsa-miR-6499-3p (MIRT776275)
- hsa-miR-6516-5p (MIRT777135)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC11
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Clone products for research
- Applied Biological Materials (abm): Clones for H2AC11 - Starting at $45 >
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- Sino Biological Human cDNA Clone for H2AC11
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Cell Lines for research
-
Horizon Cell Lines for H2AC11
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2AC11 Gene
Localization for H2AC11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2AC11 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| cytosol | 1 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | IBA | -- |
| GO:0000786 | nucleosome | IEA | -- |
| GO:0005634 | nucleus | IEA,IDA | 16319397 |
| GO:0005694 | chromosome | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | 20458337 |
Pathways & Interactions for H2AC11 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.35
|
|
| 2 | Chromatin organization | ||
| 3 | Deubiquitination |
.74
|
|
| 4 | Metabolism of proteins | ||
| 5 | Necroptosis | ||
Pathways by source for H2AC11 Gene
11 Reactome pathways for H2AC11 Gene
4 KEGG pathways for H2AC11 Gene
1 GeneGo (Thomson Reuters) pathway for H2AC11 Gene
- Signal transduction Activin A signaling regulation
Interacting Proteins for H2AC11 Gene
Selected Interacting proteins:
P0C0S8-H2A1_HUMAN
ENSP00000352119
for H2AC11 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for H2AC11
SIGNOR curated interactions for H2AC11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006342 | chromatin silencing | IBA | 21873635 |
| GO:0008150 | biological_process | ND | -- |
Drugs & Compounds for H2AC11 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6959 |
Transcripts for H2AC11 Gene
mRNA/cDNA for H2AC11 Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000359193 2250 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for H2AC11 - Starting at $85 >
- * H2AC11 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H2AC11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC11
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC11
- Browse OriGene Inhibitory RNA Products For H2AC11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC11
Clone products for research
- Applied Biological Materials (abm): Clones for H2AC11 - Starting at $45 >
- * H2AC11 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for H2AC11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC11
Relevant External Links for H2AC11 Gene
- GeneLoc Exon Structure for
- H2AC11
Expression for H2AC11 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2AC11
SOURCE GeneReport for Unigene cluster for H2AC11 Gene:
Hs.51011Evidence on tissue expression from TISSUES for H2AC11 Gene
- Intestine(4.4)
- Spleen(4.3)
No Expression Related Data Available
Primer products for research
-
OriGene qPCR primer pairs for H2AC11
-
OriGene qPCR primer pairs and template standards for H2AC11
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2AC11 Gene
Orthologs for H2AC11 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HIST1H2AG 30 |
|
OneToOne | |
| LOC736529 29 |
|
||||
| Cow (Bos Taurus) |
Mammalia | HIST1H2AG 30 |
|
OneToOne | |
| LOC529277 29 |
|
||||
| Dog (Canis familiaris) |
Mammalia | -- 30 |
|
ManyToMany | |
| LOC488297 29 |
|
||||
| Mouse (Mus musculus) |
Mammalia | Hist1h2af 30 |
|
ManyToMany | |
| Hist1h2an 29 |
|
||||
| H2ac22 16 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 30 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 30 |
|
ManyToMany | |
| Rat (Rattus norvegicus) |
Mammalia | Hist1h2ai 29 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | -- 30 |
|
ManyToMany | |
| -- 30 |
|
ManyToMany | |||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc56329 29 |
|
||
| Wheat (Triticum aestivum) |
Liliopsida | Ta.644 29 |
|
- Species where no ortholog for H2AC11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Worm (Caenorhabditis elegans)
Evolution for H2AC11 Gene
- ENSEMBL:
- Gene Tree for H2AC11 (if available)
- TreeFam:
- Gene Tree for H2AC11 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2AC11: view image
- Alliance of Genome Resources:
- Additional Orthologs for H2AC11
Paralogs for H2AC11 Gene
Paralogs for H2AC11 Gene
Variants for H2AC11 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1029124 | CNV | loss | 25217958 |
| nsv970090 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
25.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.39;
8.59% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2AC11 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2AC11 Gene
Disorders for H2AC11 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| riddle syndrome |
|
|
Search H2AC11 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for H2AC11
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for H2AC11 Gene
Publications for H2AC11 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- The relative expression of human histone H2A genes is similar in different types of proliferating cells. (PMID: 8179821) Mannironi C … Bonner W (DNA and cell biology 1994) 2 3 4
- Precise characterization of human histones in the H2A gene family by top down mass spectrometry. (PMID: 16457589) Boyne MT … Kelleher NL (Journal of proteome research 2006) 3 4
- The human H2A and H2B histone gene complement. (PMID: 10064132) Albig W … Doenecke D (Biological chemistry 1999) 3 4
- The human histone gene cluster at the D6S105 locus. (PMID: 9439656) Albig W … Doenecke D (Human genetics 1997) 3 4
ExternalLinks
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- Invitrogen Antibodies for H2AC11 (AFLGC-H2AC11)
- VectorBuilder Custom and pre-made DNA vectors for H2AC11 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2AC11 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2AC11 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2AC11 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2AC11
- antibodies-online: Show 14 available HIST1H2AG Antibodies ranked by validation data
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- antibodies-online: Search results for available HIST1H2AG related products ranked by validation data
- antibodies-online: Show 9 available HIST1H2AG Proteins ranked by validation data
- Compare Top HIST1H2AG Proteins
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- Horizon Cell Lines for H2AC11
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2AC11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC11
Sources for H2AC11 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources