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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with... See more...
Aliases for H2AC1 Gene
Aliases for H2AC1 Gene
External Ids for H2AC1 Gene
- HGNC: 18729
- Entrez Gene: 221613
- Ensembl: ENSG00000164508
- OMIM: 613499
- UniProtKB: Q96QV6
Previous HGNC Symbols for H2AC1 Gene
- HIST1H2AA
Previous GeneCards Identifiers for H2AC1 Gene
- GC06M025816
- GC06M025827
Summaries for H2AC1 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
GeneCards Summary for H2AC1 Gene
H2AC1 (H2A Clustered Histone 1) is a Protein Coding gene. Diseases associated with H2AC1 include Amelogenesis Imperfecta, Type Iiia and Riddle Syndrome. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. An important paralog of this gene is H2AC21.
UniProtKB/Swiss-Prot Summary for H2AC1 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Additional gene information for H2AC1 Gene
- HGNC(18729)
- Entrez Gene(221613)
- Ensembl(ENSG00000164508)
- OMIM(613499)
- UniProtKB(Q96QV6)
- Open Targets Platform(ENSG00000164508)
- Search for H2AC1 at DataMed
- Search for H2AC1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H2AC1 Gene
Genomics for H2AC1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H2AC1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H2AC1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H2AC1
Genomic Locations for H2AC1 Gene
Genomic Locations for H2AC1 Gene
- chr6:25,726,063-25,726,562
- (GRCh38/hg38)
- Size:
- 500 bases
- Orientation:
- Minus strand
- chr6:25,726,291-25,726,790
- (GRCh37/hg19)
- Size:
- 500 bases
- Orientation:
- Minus strand
Genomic View for H2AC1 Gene
Genes around H2AC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by HGNC
- 6p22.2 by Entrez Gene
- 6p22.2 by Ensembl
H2AC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H2AC1 Gene
Proteins for H2AC1 Gene
-
Protein details for H2AC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96QV6-H2A1A_HUMAN
- Recommended name:
- Histone H2A type 1-A
- Protein Accession:
- Q96QV6
Protein attributes for H2AC1 Gene
- Size:
- 131 amino acids
- Molecular mass:
- 14234 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Post-translational modifications for H2AC1 Gene
- Deiminated on Arg-4 in granulocytes upon calcium entry.
- Monoubiquitination of Lys-120 (H2AK119Ub) by RING1, TRIM37 and RNF2/RING2 complex gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It is involved in the initiation of both imprinted and random X inactivation. Ubiquitinated H2A is enriched in inactive X chromosome chromatin. Ubiquitination of H2A functions downstream of methylation of 'Lys-27' of histone H3 (H3K27me). H2AK119Ub by RNF2/RING2 can also be induced by ultraviolet and may be involved in DNA repair. Monoubiquitination of Lys-120 (H2AK119Ub) by TRIM37 may promote transformation of cells in a number of breast cancers (PubMed:25470042). Following DNA double-strand breaks (DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties by the E2 ligase UBE2N and the E3 ligases RNF8 and RNF168, leading to the recruitment of repair proteins to sites of DNA damage. Ubiquitination at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) in response to DNA damage is initiated by RNF168 that mediates monoubiquitination at these 2 sites, and 'Lys-63'-linked ubiquitin are then conjugated to monoubiquitin; RNF8 is able to extend 'Lys-63'-linked ubiquitin chains in vitro. Deubiquitinated by USP51 at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) after damaged DNA is repaired (PubMed:27083998). H2AK119Ub and ionizing radiation-induced 'Lys-63'-linked ubiquitination (H2AK13Ub and H2AK15Ub) are distinct events.
- Phosphorylation on Ser-2 (H2AS1ph) is enhanced during mitosis. Phosphorylation on Ser-2 by RPS6KA5/MSK1 directly represses transcription. Acetylation of H3 inhibits Ser-2 phosphorylation by RPS6KA5/MSK1. Phosphorylation at Thr-121 (H2AT120ph) by DCAF1 is present in the regulatory region of many tumor suppresor genes and down-regulates their transcription.
- Glutamine methylation at Gln-105 (H2AQ104me) by FBL is specifically dedicated to polymerase I. It is present at 35S ribosomal DNA locus and impairs binding of the FACT complex (PubMed:24352239).
- Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage.
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
-
Ubiquitination at Lys14 and Lys16
- NX_Q96QV6 (NX_Q96QV6-1)
- Modification sites at PhosphoSitePlus
Other Protein References for H2AC1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- antibodies-online: Show 48 available HIST1H2AA Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for H2AC1
- Search Origene for MassSpec and Protein Over-expression Lysates for H2AC1
- Origene Custom Protein Services for H2AC1
- Novus Biologicals lysates for H2AC1
No data available for DME Specific Peptides for H2AC1 Gene
Domains & Families for H2AC1 Gene
Gene Families for H2AC1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for H2AC1 Gene
- InterPro:
- Blocks:
-
- Histone H2A
- ProtoNet:
Suggested Antigen Peptide Sequences for H2AC1 Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H2A/r (H2A1A_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96QV6- Family:
-
- Belongs to the histone H2A family.
Function for H2AC1 Gene
Molecular function for H2AC1 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phenotypes From GWAS Catalog for H2AC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA | 21873635 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for H2AC1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2AC1 - Select products 50% OFF >
- * H2AC1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2AC1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC1
miRNA for H2AC1 Gene
- miRTarBase miRNAs that target H2AC1
-
- hsa-miR-34a-5p (MIRT025388)
- hsa-miR-5693 (MIRT523270)
- hsa-miR-8057 (MIRT523271)
- hsa-miR-6802-5p (MIRT523272)
- hsa-miR-6822-3p (MIRT523273)
- hsa-miR-4766-5p (MIRT523274)
- hsa-miR-146a-3p (MIRT523275)
- hsa-miR-6865-5p (MIRT523276)
- hsa-miR-6815-5p (MIRT523277)
- hsa-miR-1276 (MIRT523278)
- hsa-miR-760 (MIRT523279)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC1
- Browse OriGene Inhibitory RNA Products For H2AC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC1
Clone Products
- Applied Biological Materials (abm): Clones for H2AC1 - Select products 50% OFF >
- * H2AC1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2AC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC1
Cell Line Products
-
Horizon Cell Lines for H2AC1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for H2AC1 Gene
Localization for H2AC1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H2AC1 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000784 | nuclear chromosome, telomeric region | HDA | 19135898 |
| GO:0000786 | nucleosome | IEA | -- |
| GO:0000790 | nuclear chromatin | IBA | 21873635 |
| GO:0005634 | nucleus | IEA,HDA | 21630459 |
| GO:0005694 | chromosome | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for H2AC1 Gene
Pathways & Interactions for H2AC1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.35
|
|
| 2 | Chromatin organization | ||
| 3 | Deubiquitination |
.74
|
|
| 4 | Metabolism of proteins | ||
| 5 | Chromatin Regulation / Acetylation | ||
Pathways by source for H2AC1 Gene
11 Reactome pathways for H2AC1 Gene
3 KEGG pathways for H2AC1 Gene
1 Cell Signaling Technology pathway for H2AC1 Gene
Interacting Proteins for H2AC1 Gene
Selected Interacting proteins:
Q96QV6-H2A1A_HUMAN
ENSP00000297012
for H2AC1 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for H2AC1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | IEA,IBA | 21873635 |
| GO:0006342 | chromatin silencing | IBA | 21873635 |
No data available for SIGNOR curated interactions for H2AC1 Gene
Drugs & Compounds for H2AC1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6556 |
Transcripts for H2AC1 Gene
mRNA/cDNA for H2AC1 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000297012 500 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for H2AC1 - Select products 50% OFF >
- * H2AC1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for H2AC1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC1
- Browse OriGene Inhibitory RNA Products For H2AC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC1
Clone Products
- Applied Biological Materials (abm): Clones for H2AC1 - Select products 50% OFF >
- * H2AC1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for H2AC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC1
Relevant External Links for H2AC1 Gene
- GeneLoc Exon Structure for
- H2AC1
Expression for H2AC1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H2AC1
SOURCE GeneReport for Unigene cluster for H2AC1 Gene:
Hs.406739Evidence on tissue expression from TISSUES for H2AC1 Gene
- Nervous system(2.2)
- Blood(2.1)
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for H2AC1
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for H2AC1 Gene
Orthologs for H2AC1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HIST1H2AA 31 |
|
OneToOne | |
| LOC462486 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | HIST1H2AA 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Hist1h2ak 30 |
|
||
| H2ac15 17 |
|
||||
| Cow (Bos Taurus) |
Mammalia | HIST1H2AG 30 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:163047 31 |
|
ManyToMany | |
| zgc:101846 31 |
|
ManyToMany | |||
| si:ch211-113a14.19 31 31 31 31 31 31 |
|
ManyToMany | |||
| zgc:195633 31 31 31 |
|
ManyToMany | |||
| zgc:154164 31 31 |
|
ManyToMany |
- Species where no ortholog for H2AC1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for H2AC1 Gene
- ENSEMBL:
- Gene Tree for H2AC1 (if available)
- TreeFam:
- Gene Tree for H2AC1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H2AC1: view image
Paralogs for H2AC1 Gene
Paralogs for H2AC1 Gene
Pseudogenes.org Pseudogenes for H2AC1 Gene
Variants for H2AC1 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3570813 | CNV | loss | 25503493 |
Residual Variation Intolerance Score:
15.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.34;
7.46% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H2AC1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- H2AC1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H2AC1 Gene
Disorders for H2AC1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| amelogenesis imperfecta, type iiia |
|
|
| riddle syndrome |
|
|
Search H2AC1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for H2AC1
No data available for UniProtKB/Swiss-Prot and Genatlas for H2AC1 Gene
Publications for H2AC1 Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff WF … Maltais LJ (Genomics 2002) 2 3 4
- DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. (PMID: 16702407) Bergink S … Dantuma NP (Genes & development 2006) 3 4
- Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes. (PMID: 15823041) Hagiwara T … Yamada M (Biochemistry 2005) 3 4
- Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. (PMID: 16359901) Cao R … Zhang Y (Molecular cell 2005) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for H2AC1 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H2AC1
- Search Origene for MassSpec and Protein Over-expression Lysates for H2AC1
- Origene Custom Protein Services for H2AC1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H2AC1
- Browse OriGene Inhibitory RNA Products For H2AC1
- OriGene qPCR primer pairs for H2AC1
- OriGene CRISPR knockouts for H2AC1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H2AC1
- Sino Biological Human cDNA Clone for H2AC1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals lysates for H2AC1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder Custom and pre-made DNA vectors for H2AC1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H2AC1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H2AC1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H2AC1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H2AC1
- antibodies-online: Show 48 available HIST1H2AA Antibodies ranked by validation data
- antibodies-online: Search results for available HIST1H2AA related products ranked by validation data
- antibodies-online: Search results for available HIST1H2AA related products ranked by validation data
- Horizon Cell Lines for H2AC1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H2AC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H2AC1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H2AC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H2AC1
Sources for H2AC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB