Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in ... See more...

Aliases for H1-12P Gene

Aliases for H1-12P Gene

  • H1.12 Linker Histone, Cluster Member Pseudogene 2 3 5
  • Histone Cluster 1 H1 Pseudogene 1 2 3
  • Histone 1, H1, Pseudogene 1 2 3
  • DJ34B20.16 2 3
  • H1F6P 2 3
  • HIST1H1PS1 3
  • FLJ39701 2
  • H1-12P 5

External Ids for H1-12P Gene

Previous HGNC Symbols for H1-12P Gene

  • HIST1H1PS1

Previous GeneCards Identifiers for H1-12P Gene

  • GC06P027642
  • GC06P028368

Summaries for H1-12P Gene

Entrez Gene Summary for H1-12P Gene

  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This histone pseudogene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Oct 2015]

GeneCards Summary for H1-12P Gene

H1-12P (H1.12 Linker Histone, Cluster Member Pseudogene) is a Pseudogene.

Additional gene information for H1-12P Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H1-12P Gene

Genomics for H1-12P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for H1-12P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J026154 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 12.4 -37.3 -37267 7 ARHGAP35 SP1 HNRNPL CREB1 ARID3A TEAD4 PRDM10 ZNF629 REST TFE3 H2BC5 H1-4 MN298275 lnc-HIST1H4D-2 lnc-HIST1H4D-3 piR-52250 piR-40328 piR-58207 piR-57285-001 ABT1
GH06J026193 Promoter/Enhancer 2.1 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +5.2 5238 14.6 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ATF7 TEAD4 PRDM10 REST ZNF629 H2AC7 H2BC7 H3C4 ENSG00000282988 RPS10P1 ABT1 BTN2A2 BTN2A1 HMGN4 BTN2A3P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around H1-12P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for H1-12P Gene

Genomic Locations for H1-12P Gene
chr6:26,195,554-26,196,633
(GRCh38/hg38)
Size:
1,080 bases
Orientation:
Plus strand
chr6:26,195,794-26,195,999
(GRCh37/hg19)
Size:
206 bases
Orientation:
Plus strand

Genomic View for H1-12P Gene

Genes around H1-12P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
H1-12P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for H1-12P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for H1-12P Gene

Proteins for H1-12P Gene

Post-translational modifications for H1-12P Gene

No Post-translational modifications

No data available for DME Specific Peptides for H1-12P Gene

Domains & Families for H1-12P Gene

Gene Families for H1-12P Gene

HGNC:
genes like me logo Genes that share domains with H1-12P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for H1-12P Gene

Function for H1-12P Gene

Phenotypes From GWAS Catalog for H1-12P Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for H1-12P Gene

Localization for H1-12P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for H1-12P Gene

Pathways & Interactions for H1-12P Gene

PathCards logo

SuperPathways for H1-12P Gene

No Data Available

Gene Ontology (GO) - Biological Process for H1-12P Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for H1-12P Gene

Drugs & Compounds for H1-12P Gene

No Compound Related Data Available

Transcripts for H1-12P Gene

mRNA/cDNA for H1-12P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for H1-12P Gene

No ASD Table

Relevant External Links for H1-12P Gene

GeneLoc Exon Structure for
H1-12P

Expression for H1-12P Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for H1-12P Gene

Orthologs for H1-12P Gene

Evolution for H1-12P Gene

ENSEMBL:
Gene Tree for H1-12P (if available)
TreeFam:
Gene Tree for H1-12P (if available)

No data available for Orthologs for H1-12P Gene

Paralogs for H1-12P Gene

No data available for Paralogs for H1-12P Gene

Variants for H1-12P Gene

Additional Variant Information for H1-12P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
H1-12P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for H1-12P Gene

Disorders for H1-12P Gene

No disorders were found for H1-12P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for H1-12P Gene

Publications for H1-12P Gene

No publications were found for H1-12P Gene.

No data available for Mastermind for H1-12P Gene

Products for H1-12P Gene

Sources for H1-12P Gene