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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with... See more...
Aliases for H1-0 Gene
Aliases for H1-0 Gene
External Ids for H1-0 Gene
- HGNC: 4714
- NCBI Entrez Gene: 3005
- Ensembl: ENSG00000189060
- OMIM®: 142708
- UniProtKB/Swiss-Prot: P07305
Previous HGNC Symbols for H1-0 Gene
- H1FV
- H1F0
Previous GeneCards Identifiers for H1-0 Gene
- GC22P037806
- GC22P037822
- GC22P037837
- GC22P037857
Summaries for H1-0 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
GeneCards Summary for H1-0 Gene
H1-0 (H1.0 Linker Histone) is a Protein Coding gene. Diseases associated with H1-0 include Spherocytosis, Type 1 and Hyperoxaluria, Primary, Type I. Among its related pathways are Activation of DNA fragmentation factor and DNA Damage/Telomere Stress Induced Senescence. An important paralog of this gene is H1-4.
UniProtKB/Swiss-Prot Summary for H1-0 Gene
-
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Additional gene information for H1-0 Gene
- HGNC (4714)
- NCBI Entrez Gene (3005)
- Ensembl (ENSG00000189060)
- OMIM® (142708)
- UniProtKB/Swiss-Prot (P07305)
- Open Targets Platform(ENSG00000189060)
- Alliance of Genome Resources
- Search for H1-0 at DataMed
- Search for H1-0 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for H1-0 Gene
Genomics for H1-0 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for H1-0 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around H1-0 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for H1-0
Genomic Locations for H1-0 Gene
Latest Assembly
- chr22:37,805,093-37,807,436
- (GRCh38/hg38)
- Size:
- 2,344 bases
- Orientation:
- Plus strand
Previous Assembly
- chr22:38,201,236-38,203,439
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 2,204 bases
- Orientation:
- Plus strand
Genomic View for H1-0 Gene
Genes around H1-0 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by HGNC
- 22q13.1 by Entrez Gene
- 22q13.1 by Ensembl
H1-0 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for H1-0 Gene
Proteins for H1-0 Gene
-
Protein details for H1-0 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P07305-H10_HUMAN
- Recommended name:
- Histone H1.0
- Protein Accession:
- P07305
- B2R6I0
- B4DRD6
- Q6FG88
- Q8N6R3
Protein attributes for H1-0 Gene
- Size:
- 194 amino acids
- Molecular mass:
- 20863 Da
- Quaternary structure:
- No Data Available
Three dimensional structures from OCA and Proteopedia for H1-0 Gene
Post-translational modifications for H1-0 Gene
- Phosphorylated on Ser-17 in RNA edited version.
- ADP-ribosylated on Ser-104 in response to DNA damage.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for H1-0 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ Histone H1.0 Antibody and Immunotag™ Histone 1F0 Antibody
- GeneTex Anti-Histone H1.0 antibody
- NSJ Bioreagents Histone H1 Antibody (Mouse Monoclonal)
-
Custom Antibody ServicesOriGene Antibodies for H1-0
- Novus Biologicals Antibodies for H1-0
-
Abcam antibodies for H1-0
- Invitrogen Antibodies for H1-0 (AFLGC-H1-0)
-
Custom Antibody ServicesProSci Antibodies for H1-0
- Sino Biological Antibodies for H1-0
Protein products for research
-
OriGene Purified Proteins for H1-0
- Search Origene for MassSpec and Protein Over-expression Lysates for H1-0
- Origene Custom Protein Services for H1-0
- Sino Biological Recombinant Proteins for H1-0
- Browse Sino Biological Cell Lysates
-
Abcam proteins for H1-0
Assay products for research
- antibodies-online: Show 4 available Histone H1 Elisa Kits ranked by validation data
- Compare Top Histone H1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for H1-0 Gene
Domains & Families for H1-0 Gene
Gene Families for H1-0 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for H1-0 Gene
- InterPro:
- Blocks:
-
- Histone H1/H5
- Linker histone, N-terminal
- Histone H5 signature
Suggested Antigen Peptide Sequences for H1-0 Gene
- GenScript: Design optimal peptide antigens:
-
- Histone H1(0) (H10_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P07305- Family:
-
- Belongs to the histone H1/H5 family.
Function for H1-0 Gene
Molecular function for H1-0 Gene
- UniProtKB/Swiss-Prot Function:
- Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
- UniProtKB/Swiss-Prot Induction:
- Both the unedited and the RNA edited versions are induced by butyrate (at protein level). Only RNA edited version is induced by DTT, vinblastine or TNF (at protein level).
Phenotypes From GWAS Catalog for H1-0 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003680 | AT DNA binding | IEA | -- |
| GO:0003690 | double-stranded DNA binding | IEA,IBA | 21873635 |
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0005515 | protein binding | IPI | 9499053 |
Phenotypes for H1-0 Gene
- MGI mutant phenotypes for H1-0:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for H1-0:
-
- no effect
- Decreased viability ratio
- Increased cell death HMECs cells
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Increased Nanog expression
- Increased G2M DNA content
- Decreased Salmonella enterica Typhimurium invasion
- Decreased viability in esophageal squamous lineage; decreased viability in non-small-cell lung cancer (NSCLC) lineage
Animal Models for H1-0 Gene
- MGI Knock Outs for H1-0:
-
- H1f0 H1f0<tm1Ais>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for H1-0 - Starting at $85 >
- * H1-0 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H1-0
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H1-0
miRNA for H1-0 Gene
- miRTarBase miRNAs that target H1-0
-
- hsa-miR-181a-5p (MIRT025115)
- hsa-miR-615-3p (MIRT040432)
- hsa-miR-484 (MIRT041752)
- hsa-miR-423-3p (MIRT042482)
- hsa-miR-186-5p (MIRT045076)
- hsa-miR-93-5p (MIRT048807)
- hsa-let-7a-5p (MIRT052457)
- hsa-miR-410-5p (MIRT087755)
- hsa-miR-494-5p (MIRT087756)
- hsa-miR-509-3p (MIRT087758)
- hsa-miR-744-3p (MIRT087759)
- hsa-miR-323b-5p (MIRT087760)
- hsa-miR-4760-5p (MIRT087763)
- hsa-miR-8061 (MIRT087764)
- hsa-miR-502-5p (MIRT119630)
- hsa-miR-6841-3p (MIRT119633)
- hsa-miR-3148 (MIRT301400)
- hsa-miR-376a-5p (MIRT507075)
- hsa-miR-6876-3p (MIRT507076)
- hsa-miR-626 (MIRT507077)
- hsa-miR-6870-3p (MIRT507078)
- hsa-miR-1915-5p (MIRT507079)
- hsa-miR-3915 (MIRT529601)
- hsa-miR-519e-5p (MIRT529602)
- hsa-miR-515-5p (MIRT529603)
- hsa-miR-1298-5p (MIRT529604)
- hsa-miR-3928-3p (MIRT529605)
- hsa-miR-676-5p (MIRT529606)
- hsa-miR-3925-3p (MIRT529607)
- hsa-miR-766-3p (MIRT529608)
- hsa-miR-520h (MIRT529609)
- hsa-miR-520g-3p (MIRT529610)
- hsa-miR-3973 (MIRT529611)
- hsa-miR-664a-3p (MIRT529612)
- hsa-miR-548ah-5p (MIRT529613)
- hsa-miR-3609 (MIRT529614)
- hsa-miR-122-5p (MIRT736107)
- hsa-miR-1249-5p (MIRT736433)
- hsa-miR-181b-5p (MIRT738034)
- hsa-miR-181c-5p (MIRT738041)
- hsa-miR-181d-5p (MIRT738049)
- hsa-miR-4262 (MIRT743484)
- hsa-miR-4419a (MIRT744179)
- hsa-miR-4459 (MIRT744800)
- hsa-miR-4510 (MIRT745618)
- hsa-miR-4669 (MIRT746834)
- hsa-miR-4779 (MIRT748733)
- hsa-miR-6127 (MIRT752093)
- hsa-miR-6129 (MIRT752165)
- hsa-miR-6130 (MIRT752254)
- hsa-miR-6133 (MIRT752358)
- hsa-miR-6797-5p (MIRT756193)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H1-0
- Browse OriGene Inhibitory RNA Products For H1-0
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H1-0
Clone products for research
- Applied Biological Materials (abm): Clones for H1-0 - Starting at $45 >
- * H1-0 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for H1-0
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H1-0
Cell Lines for research
-
Horizon Cell Lines for H1-0
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for H1-0 Gene
Localization for H1-0 Gene
Subcellular locations from UniProtKB/Swiss-Prot for H1-0 Gene
- Nucleus. Chromosome. Note=The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| extracellular | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endosome | 1 |
| lysosome | 1 |
- Nuclear bodies (3)
- Nucleoplasm (3)
- Actin filaments (1)
- Golgi apparatus (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | IDA | 19882353 |
| GO:0000786 | nucleosome | IEA | -- |
| GO:0000791 | euchromatin | IDA | 15911621 |
| GO:0005634 | nucleus | IBA,IDA | 21383955 |
| GO:0005654 | nucleoplasm | TAS | -- |
Pathways & Interactions for H1-0 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activation of DNA fragmentation factor | ||
| 2 | CDK-mediated phosphorylation and removal of Cdc6 |
.31
|
|
| 3 | Cellular Senescence (REACTOME) | ||
| 4 | DNA Damage/Telomere Stress Induced Senescence | ||
| 5 | Granzyme-A Pathway |
Granzyme-A Pathway
-
|
|
Pathways by source for H1-0 Gene
9 Reactome pathways for H1-0 Gene
2 GeneGo (Thomson Reuters) pathways for H1-0 Gene
- Cell cycle Start of DNA replication in early S phase
- Cell cycle_Chromosome condensation in prometaphase
2 Qiagen pathways for H1-0 Gene
- Granzyme-A Pathway
- PKA Signaling
1 GeneTex pathway for H1-0 Gene
Interacting Proteins for H1-0 Gene
Selected Interacting proteins:
P07305-H10_HUMAN
ENSP00000344504
for H1-0 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for H1-0
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IGI | 19158276 |
| GO:0006309 | apoptotic DNA fragmentation | TAS | -- |
| GO:0006334 | nucleosome assembly | IEA | -- |
| GO:0006342 | chromatin silencing | IGI | 19158276 |
| GO:0016584 | nucleosome positioning | IBA | 21873635 |
No data available for SIGNOR curated interactions for H1-0 Gene
Transcripts for H1-0 Gene
mRNA/cDNA for H1-0 Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000340857 2344 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for H1-0 - Starting at $85 >
- * H1-0 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for H1-0
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H1-0
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H1-0
- Browse OriGene Inhibitory RNA Products For H1-0
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H1-0
Clone products for research
- Applied Biological Materials (abm): Clones for H1-0 - Starting at $45 >
- * H1-0 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for H1-0
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H1-0
Relevant External Links for H1-0 Gene
- GeneLoc Exon Structure for
- H1-0
Expression for H1-0 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for H1-0
SOURCE GeneReport for Unigene cluster for H1-0 Gene:
Hs.745024Evidence on tissue expression from TISSUES for H1-0 Gene
- Nervous system(5)
- Intestine(4.7)
- Liver(3.9)
- Skin(3.2)
- Kidney(3.1)
- Bone marrow(3.1)
- Muscle(3)
- Lung(2.9)
- Heart(2.8)
- Blood(2.7)
- Thyroid gland(2.7)
- Stomach(2.5)
- Spleen(2.5)
- Pancreas(2.5)
- Bone(2.4)
- Adrenal gland(2.3)
- Lymph node(2.2)
- Gall bladder(2)
No Expression Related Data Available
Primer products for research
-
OriGene qPCR primer pairs for H1-0
-
OriGene qPCR primer pairs and template standards for H1-0
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for H1-0 Gene
Orthologs for H1-0 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | H1F0 30 |
|
OneToOne | |
| LOC743278 29 |
|
||||
| Cow (Bos Taurus) |
Mammalia | H1F0 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | H1f0 29 16 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | H1F0 30 30 |
|
OneToMany | |
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398662 29 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.4764 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | h1f0 30 |
|
OneToOne | |
| wufb23b02 29 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10060 29 |
|
- Species where no ortholog for H1-0 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for H1-0 Gene
- ENSEMBL:
- Gene Tree for H1-0 (if available)
- TreeFam:
- Gene Tree for H1-0 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for H1-0: view image
- Alliance of Genome Resources:
- Additional Orthologs for H1-0
Paralogs for H1-0 Gene
Variants for H1-0 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758838 | CNV | loss | 17122850 |
Residual Variation Intolerance Score:
34.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.30;
6.70% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for H1-0 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for H1-0 Gene
Disorders for H1-0 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spherocytosis, type 1 |
|
|
| hyperoxaluria, primary, type i |
|
|
| cockayne syndrome |
|
|
| primary hyperoxaluria |
|
|
| ceroid lipofuscinosis, neuronal, 2 |
|
|
Search H1-0 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for H1-0
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for H1-0 Gene
Publications for H1-0 Gene
- Differential distribution of lysine and arginine residues in the closely related histones H1 and H5. Analysis of a human H1 gene. (PMID: 3084796) Doenecke D … Tönjes R (Journal of molecular biology 1986) 2 3 4
- A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 3 4
ExternalLinks
Products for H1-0 Gene
- Custom Antibody ServicesOriGene Antibodies for H1-0
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for H1-0
- Search Origene for MassSpec and Protein Over-expression Lysates for H1-0
- Origene Custom Protein Services for H1-0
- Origene shrna, sirna, and RNAi products in human, mouse, rat for H1-0
- Browse OriGene Inhibitory RNA Products For H1-0
- OriGene qPCR primer pairs for H1-0
- OriGene qPCR primer pairs and template standards for H1-0
- OriGene CRISPR knockouts for H1-0
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For H1-0
- Sino Biological Human cDNA Clone for H1-0
- Sino Biological Recombinant Proteins for H1-0
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for H1-0
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for H1-0
- Novus Biologicals proteins and lysates for H1-0
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for H1-0
- Abcam proteins for H1-0
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for H1-0 (AFLGC-H1-0)
- VectorBuilder Custom and pre-made DNA vectors for H1-0 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for H1-0 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for H1-0 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for H1-0 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for H1-0
- antibodies-online: Show 133 available Histone H1 Antibodies ranked by validation data
- Compare Top Histone H1 Antibodies
- antibodies-online: Show 4 available Histone H1 Elisa Kits ranked by validation data
- Compare Top Histone H1 Elisa Kits
- Quality Products:
- antibodies-online: Show 11 available Histone H1 Proteins ranked by validation data
- Compare Top Histone H1 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for H1-0
- Search for H1-0 Proteins at ProSci
- Horizon Cell Lines for H1-0
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for H1-0
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for H1-0
- Search GeneCopoeia for miRNA 3'UTR Target clone products for H1-0
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for H1-0
Sources for H1-0 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources