Aliases for GYG2 Gene
External Ids for GYG2 Gene
Previous GeneCards Identifiers for GYG2 Gene
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
GeneCards Summary for GYG2 Gene
GYG2 (Glycogenin 2) is a Protein Coding gene. Diseases associated with GYG2 include Glycogen Storage Disease Type 0 and Retinitis Pigmentosa 36. Among its related pathways are Glycogen storage diseases and Glycosaminoglycan metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring glycosyl groups and glycogenin glucosyltransferase activity. An important paralog of this gene is GYG1.
UniProtKB/Swiss-Prot for GYG2 Gene
Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.