Aliases for GXYLT2 Gene
External Ids for GXYLT2 Gene
Previous HGNC Symbols for GXYLT2 Gene
Previous GeneCards Identifiers for GXYLT2 Gene
The protein encoded by this gene is a xylosyltransferase that elongates O-linked glucose bound to epidermal growth factor (EGF) repeats. The encoded protein catalyzes the addition of xylose to the O-glucose-modified residues of EGF repeats of Notch proteins. [provided by RefSeq, Sep 2016]
GeneCards Summary for GXYLT2 Gene
GXYLT2 (Glucoside Xylosyltransferase 2) is a Protein Coding gene. Diseases associated with GXYLT2 include Inflammatory Bowel Disease 19 and Mandibulofacial Dysostosis With Alopecia. Among its related pathways are Mucin type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring glycosyl groups and UDP-xylosyltransferase activity. An important paralog of this gene is GXYLT1.
UniProtKB/Swiss-Prot Summary for GXYLT2 Gene
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.