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Aliases for GVINP1 Gene

Aliases for GVINP1 Gene

  • GTPase, Very Large Interferon Inducible Pseudogene 1 2 3 5
  • GTPase, Very Large Interferon Inducible 1, Pseudogene 2 3
  • Very Large Inducible GTPase 1 2 3
  • GVIN1 3 4
  • VLIG1 3 4
  • Interferon-Induced Very Large GTPase Pseudogene 1 4
  • GTPase, Very Large Interferon Inducible 1 2
  • VLIG-1 3
  • GVIN1P 3

External Ids for GVINP1 Gene

Previous HGNC Symbols for GVINP1 Gene

  • GVIN1
  • GVIN1P

Previous GeneCards Identifiers for GVINP1 Gene

  • GC11M006735

Summaries for GVINP1 Gene

GeneCards Summary for GVINP1 Gene

GVINP1 (GTPase, Very Large Interferon Inducible Pseudogene 1) is a Pseudogene. Diseases associated with GVINP1 include Gtpase, Very Large Interferon-Inducible, Pseudogene 1. Gene Ontology (GO) annotations related to this gene include GTP binding.

Additional gene information for GVINP1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GVINP1 Gene

Genomics for GVINP1 Gene

GeneHancer (GH) Regulatory Elements for GVINP1 Gene

Promoters and enhancers for GVINP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I006742 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 557.3 +1.2 1207 6.5 PKNOX1 SMAD1 YBX1 TCF12 ZNF766 ZNF207 RUNX3 JUNB ZNF592 SMARCA4 GVINP1 OR2AG2 RRP8 ILK ENSG00000254641 TAF10 OR10A4 APBB1 SMPD1 OR2AG1
GH11I006728 Enhancer 0.9 ENCODE dbSUPER 7.4 +17.9 17926 0.7 BACH1 CEBPG ZBTB40 ZNF316 MTA3 NFE2 MAFK ZNF639 SMARCE1 SOX6 GVINP1 MRPL17 GC11P006733 PIR51504
GH11I006991 Enhancer 0.8 Ensembl ENCODE 6.6 -246.0 -245966 2.5 PKNOX1 ZNF792 ZIC2 ZNF843 ZNF335 PRDM6 ZFP3 ZXDB TRIM28 ZBTB20 LOC102724711 NLRP14 ZNF214 GVINP1 ZNF215 GC11M006969 GC11P006959 GC11M006985
GH11I006733 Enhancer 0.5 ENCODE dbSUPER 7.6 +11.9 11871 2.9 JUN GC11P006733 OR2AG2 GVINP1 PIR50704
GH11I006773 Enhancer 0.6 Ensembl 5.5 -26.0 -25962 0.4 PKNOX1 ATF1 NRF1 MAFG DPF2 ZNF316 IKZF1 ZNF24 MAFK IKZF2 GVINP1 OR2AG1 GC11M006741 OR2AG2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GVINP1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GVINP1 Gene

Genomic Locations for GVINP1 Gene
chr11:6,713,139-6,746,439
(GRCh38/hg38)
Size:
33,301 bases
Orientation:
Minus strand
chr11:6,734,370-6,767,670
(GRCh37/hg19)

Genomic View for GVINP1 Gene

Genes around GVINP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GVINP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GVINP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GVINP1 Gene

Proteins for GVINP1 Gene

  • Protein details for GVINP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z2Y8-GVIN1_HUMAN
    Recommended name:
    Interferon-induced very large GTPase 1
    Protein Accession:
    Q7Z2Y8
    Secondary Accessions:
    • A6NFL2
    • Q9H8N5

    Protein attributes for GVINP1 Gene

    Size:
    2422 amino acids
    Molecular mass:
    279048 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14573.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for GVINP1 Gene

Post-translational modifications for GVINP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GVINP1 Gene

Domains & Families for GVINP1 Gene

Protein Domains for GVINP1 Gene

Suggested Antigen Peptide Sequences for GVINP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z2Y8

UniProtKB/Swiss-Prot:

GVIN1_HUMAN :
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
Family:
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
genes like me logo Genes that share domains with GVINP1: view

No data available for Gene Families for GVINP1 Gene

Function for GVINP1 Gene

Phenotypes From GWAS Catalog for GVINP1 Gene

Gene Ontology (GO) - Molecular Function for GVINP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with GVINP1: view

Phenotypes for GVINP1 Gene

GenomeRNAi human phenotypes for GVINP1:
genes like me logo Genes that share phenotypes with GVINP1: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GVINP1 Gene

Localization for GVINP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GVINP1 Gene

Cytoplasm, cytosol. Nucleus.

Gene Ontology (GO) - Cellular Components for GVINP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with GVINP1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GVINP1 Gene

Pathways & Interactions for GVINP1 Gene

SuperPathways for GVINP1 Gene

No Data Available

Interacting Proteins for GVINP1 Gene

Gene Ontology (GO) - Biological Process for GVINP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GVINP1 Gene

Drugs & Compounds for GVINP1 Gene

No Compound Related Data Available

Transcripts for GVINP1 Gene

mRNA/cDNA for GVINP1 Gene

Unigene Clusters for GVINP1 Gene

GTPase, very large interferon inducible pseudogene 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GVINP1 Gene

No ASD Table

Relevant External Links for GVINP1 Gene

GeneLoc Exon Structure for
GVINP1
ECgene alternative splicing isoforms for
GVINP1

Expression for GVINP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GVINP1 Gene

mRNA differential expression in normal tissues according to GTEx for GVINP1 Gene

This gene is overexpressed in Spleen (x6.4), Small Intestine - Terminal Ileum (x6.3), and Whole Blood (x5.2).

Protein differential expression in normal tissues from HIPED for GVINP1 Gene

This gene is overexpressed in Liver, secretome (30.9), Pancreatic juice (19.0), and Adipocyte (15.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GVINP1 Gene



Protein tissue co-expression partners for GVINP1 Gene

NURSA nuclear receptor signaling pathways regulating expression of GVINP1 Gene:

GVINP1

SOURCE GeneReport for Unigene cluster for GVINP1 Gene:

Hs.494757
genes like me logo Genes that share expression patterns with GVINP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GVINP1 Gene

Orthologs for GVINP1 Gene

Evolution for GVINP1 Gene

ENSEMBL:
Gene Tree for GVINP1 (if available)
TreeFam:
Gene Tree for GVINP1 (if available)

No data available for Orthologs for GVINP1 Gene

Paralogs for GVINP1 Gene

No data available for Paralogs for GVINP1 Gene

Variants for GVINP1 Gene

Sequence variations from dbSNP and Humsavar for GVINP1 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000020713 -- 6,721,265(-) C/A non_coding_transcript_variant
rs1000884627 -- 6,716,197(-) T/C non_coding_transcript_variant
rs1001038972 -- 6,722,378(-) G/A/C upstream_transcript_variant
rs1001299998 -- 6,722,584(-) T/C upstream_transcript_variant
rs1001469488 -- 6,722,967(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GVINP1 Gene

Variant ID Type Subtype PubMed ID
nsv1035138 CNV gain 25217958
nsv1046129 CNV loss 25217958
nsv819468 CNV loss 19587683
nsv832060 CNV gain 17160897

Additional Variant Information for GVINP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GVINP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for GVINP1 Gene

Disorders for GVINP1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for GVINP1 Gene - From: OMIM and GeneCards

Disorder Aliases PubMed IDs
gtpase, very large interferon-inducible, pseudogene 1
  • gvinp1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for GVINP1

genes like me logo Genes that share disorders with GVINP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GVINP1 Gene

Publications for GVINP1 Gene

  1. A giant GTPase, very large inducible GTPase-1, is inducible by IFNs. (PMID: 12874213) Klamp T … Howard JC (Journal of immunology (Baltimore, Md. : 1950) 2003) 2 3 22 58
  2. The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates. (PMID: 19369598) Li G … Wang Y (Molecular biology and evolution 2009) 2 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett EJ … Harper JW (Cell 2010) 3 58
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58

Products for GVINP1 Gene

Sources for GVINP1 Gene

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