Aliases for GVINP1 Gene

Aliases for GVINP1 Gene

  • GTPase, Very Large Interferon Inducible Pseudogene 1 2 3 5
  • VLIG1 2 3 4
  • GTPase, Very Large Interferon Inducible 1, Pseudogene 2 3
  • Very Large Inducible GTPase 1 2 3
  • VLIG-1 2 3
  • GVIN1 3 4
  • Interferon-Induced Very Large GTPase Pseudogene 1 4
  • GTPase, Very Large Interferon Inducible 1 2
  • Interferon-Induced Very Large GTPase 1 4
  • FLJ13373 2
  • GVIN1P 3
  • GVINP1 5

External Ids for GVINP1 Gene

Previous HGNC Symbols for GVINP1 Gene

  • GVIN1
  • GVIN1P

Previous GeneCards Identifiers for GVINP1 Gene

  • GC11M006735

Summaries for GVINP1 Gene

GeneCards Summary for GVINP1 Gene

GVINP1 (GTPase, Very Large Interferon Inducible Pseudogene 1) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include GTP binding.

Additional gene information for GVINP1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GVINP1 Gene

Genomics for GVINP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GVINP1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J006742 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 607.2 +1.3 1307 6.7 LEF1 IKZF1 POLR2A PKNOX1 SMAD5 IKZF2 RCOR1 RELA TRIM22 DPF2 GVINP1 MRPL17 lnc-OR2AG2-1 ILK OR2AG2 CAVIN3 RRP8 ENSG00000254641 TAF10 OR10A4
GH11J006728 Enhancer 1 Ensembl ENCODE dbSUPER 7.4 +18.3 18338 3 IKZF1 DPF2 SOX6 MGA CBX3 HMBOX1 MTA3 NFE2 ZNF316 MAFG MRPL17 OR2AG2 RPL21P94 GVINP1 piR-47211-071 piR-57505
GH11J006991 Enhancer 0.8 Ensembl ENCODE 6.6 -246.0 -245966 2.5 FOXA1 ZIC2 ZNF792 ZBTB20 ZXDB CEBPB ZNF335 BHLHE40 MAFK ZFP3 NLRP14 ZNF214 GVINP1 ZNF215 lnc-ZNF214-1 piR-61580-072
GH11J006733 Enhancer 0.4 ENCODE dbSUPER 7.6 +11.9 11871 2.9 JUN lnc-OR2AG1-2 OR2AG2 GVINP1 piR-56705 lnc-OR2AG2-1 MRPL17
GH11J006717 Enhancer 0.3 Ensembl dbSUPER 7.4 +28.3 28338 1.4 piR-57505 OR2AG2 MRPL17 RPL21P94 OR2AG1 GVINP1 piR-47211-071
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GVINP1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for GVINP1 Gene

Genomic Locations for GVINP1 Gene
33,301 bases
Minus strand
33,301 bases
Minus strand

Genomic View for GVINP1 Gene

Genes around GVINP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GVINP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GVINP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GVINP1 Gene

Proteins for GVINP1 Gene

  • Protein details for GVINP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Interferon-induced very large GTPase 1
    Protein Accession:
    Secondary Accessions:
    • A6NFL2
    • Q9H8N5

    Protein attributes for GVINP1 Gene

    2422 amino acids
    Molecular mass:
    279048 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14573.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

neXtProt entry for GVINP1 Gene

Post-translational modifications for GVINP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GVINP1 Gene

Domains & Families for GVINP1 Gene

Protein Domains for GVINP1 Gene

Suggested Antigen Peptide Sequences for GVINP1 Gene

GenScript: Design optimal peptide antigens:
  • Interferon-induced very large GTPase pseudogene 1 (GVIN1_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
genes like me logo Genes that share domains with GVINP1: view

No data available for Gene Families for GVINP1 Gene

Function for GVINP1 Gene

Phenotypes From GWAS Catalog for GVINP1 Gene

Gene Ontology (GO) - Molecular Function for GVINP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with GVINP1: view

Phenotypes for GVINP1 Gene

genes like me logo Genes that share phenotypes with GVINP1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GVINP1 Gene

Localization for GVINP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GVINP1 Gene

Cytoplasm, cytosol. Nucleus.

Gene Ontology (GO) - Cellular Components for GVINP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with GVINP1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GVINP1 Gene

Pathways & Interactions for GVINP1 Gene

PathCards logo

SuperPathways for GVINP1 Gene

No Data Available

Interacting Proteins for GVINP1 Gene

Selected Interacting proteins: Q7Z2Y8-GVIN1_HUMAN for GVINP1 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for GVINP1 Gene


No data available for Pathways by source and SIGNOR curated interactions for GVINP1 Gene

Drugs & Compounds for GVINP1 Gene

No Compound Related Data Available

Transcripts for GVINP1 Gene

mRNA/cDNA for GVINP1 Gene

4 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for GVINP1 Gene

No ASD Table

Relevant External Links for GVINP1 Gene

GeneLoc Exon Structure for

Expression for GVINP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GVINP1 Gene

mRNA differential expression in normal tissues according to GTEx for GVINP1 Gene

This gene is overexpressed in Spleen (x6.4), Small Intestine - Terminal Ileum (x6.3), and Whole Blood (x5.2).

Protein differential expression in normal tissues from HIPED for GVINP1 Gene

This gene is overexpressed in Liver, secretome (30.9), Pancreatic juice (19.0), and Adipocyte (15.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GVINP1 Gene

Protein tissue co-expression partners for GVINP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GVINP1

SOURCE GeneReport for Unigene cluster for GVINP1 Gene:

genes like me logo Genes that share expression patterns with GVINP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GVINP1 Gene

Orthologs for GVINP1 Gene

Evolution for GVINP1 Gene

Gene Tree for GVINP1 (if available)
Gene Tree for GVINP1 (if available)

No data available for Orthologs for GVINP1 Gene

Paralogs for GVINP1 Gene

No data available for Paralogs for GVINP1 Gene

Variants for GVINP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for GVINP1 Gene

Variant ID Type Subtype PubMed ID
nsv1035138 CNV gain 25217958
nsv1046129 CNV loss 25217958
nsv819468 CNV loss 19587683
nsv832060 CNV gain 17160897

Additional Variant Information for GVINP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for GVINP1 Gene

Disorders for GVINP1 Gene

No disorders were found for GVINP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GVINP1 Gene

Publications for GVINP1 Gene

  1. A giant GTPase, very large inducible GTPase-1, is inducible by IFNs. (PMID: 12874213) Klamp T … Howard JC (Journal of immunology (Baltimore, Md. : 1950) 2003) 2 3 23
  2. The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates. (PMID: 19369598) Li G … Wang Y (Molecular biology and evolution 2009) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  4. Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer. (PMID: 30652415) Liu Y … Chen L (Cancer medicine 2019) 3
  5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett EJ … Harper JW (Cell 2010) 3

Products for GVINP1 Gene

Sources for GVINP1 Gene