Aliases for GUK1 Gene
External Ids for GUK1 Gene
Previous GeneCards Identifiers for GUK1 Gene
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for GUK1 Gene
GUK1 (Guanylate Kinase 1) is a Protein Coding gene. Diseases associated with GUK1 include Retinitis Pigmentosa. Among its related pathways are superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis and Metabolism. Gene Ontology (GO) annotations related to this gene include guanylate kinase activity. An important paralog of this gene is MPP7.
UniProtKB/Swiss-Prot for GUK1 Gene
Essential for recycling GMP and indirectly, cGMP.