Aliases for GUCY1A1 Gene
External Ids for GUCY1A1 Gene
Previous HGNC Symbols for GUCY1A1 Gene
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
GeneCards Summary for GUCY1A1 Gene
GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha 1) is a Protein Coding gene. Diseases associated with GUCY1A1 include Moyamoya Disease 6 With Or Without Achalasia and Moyamoya Disease 1. Among its related pathways are G-Beta Gamma Signaling and Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2. An important paralog of this gene is GUCY1A2.