Aliases for GTSCR1 Gene

Subcategory (RNA class) for GTSCR1 Gene

lncRNA

Number of RNA Genes sources:

1 / 17

Aliases for GTSCR1 Gene

  • Gilles De La Tourette Syndrome Chromosome Region, Candidate 1 2 3 5
  • Gilles De La Tourette Syndrome Chromosome Region, Candidate 1 (Non-Protein Coding) 2 3
  • Gilles De La Tourette Syndrome Chromosomal Region Candidate Gene 1 Protein 3 4
  • GTSCR1 2 5
  • Lnc-RTTN-8 165

External Ids for GTSCR1 Gene

Previous GeneCards Identifiers for GTSCR1 Gene

  • GC18M068082
  • GC18U900020
  • GC18M066448
  • GC18M068297

Summaries for GTSCR1 Gene

GeneCards Summary for GTSCR1 Gene

GTSCR1 (Gilles De La Tourette Syndrome Chromosome Region, Candidate 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with GTSCR1 include Gilles De La Tourette Syndrome and Echolalia.

Additional gene information for GTSCR1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GTSCR1 Gene

Genomics for GTSCR1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GTSCR1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J070649 Enhancer 0.3 dbSUPER 600.7 -1.4 -1418 5.4 MNT GTSCR1 LOC107985166 SOCS6
GH18J070620 Enhancer 0.9 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +28.7 28653 5 FOXA1 FOXA2 POLR2A RTTN GTSCR1 LINC01910 SOCS6
GH18J070658 Enhancer 0.6 FANTOM5 ENCODE dbSUPER 0.4 -8.4 -8422 1.3 RTTN GTSCR1 LOC107985166 SOCS6
GH18J070663 Enhancer 0.5 FANTOM5 ENCODE dbSUPER 0.4 -12.4 -12406 0.2 RTTN LOC107985166 GTSCR1 SOCS6
GH18J070627 Enhancer 0.4 Ensembl dbSUPER 0.4 +23.4 23353 0.4 CTCF GTSCR1 LINC01910 SOCS6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GTSCR1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GTSCR1

Genomic Locations for GTSCR1 Gene

Genomic Locations for GTSCR1 Gene
chr18:70,630,519-70,650,954
(GRCh38/hg38)
Size:
20,436 bases
Orientation:
Minus strand
chr18:68,297,755-68,317,980
(GRCh37/hg19)
Size:
20,226 bases
Orientation:
Minus strand

Genomic View for GTSCR1 Gene

Genes around GTSCR1 on UCSC Golden Path with GeneCards custom track
GTSCR1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
GTSCR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GTSCR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GTSCR1 Gene

Proteins for GTSCR1 Gene

  • Protein details for GTSCR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86UQ5-GTSC1_HUMAN
    Recommended name:
    Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein
    Protein Accession:
    Q86UQ5
    Secondary Accessions:
    • J3KSW9

    Protein attributes for GTSCR1 Gene

    Size:
    136 amino acids
    Molecular mass:
    15623 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GTSCR1 Gene

Post-translational modifications for GTSCR1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GTSCR1 Gene

Domains & Families for GTSCR1 Gene

Gene Families for GTSCR1 Gene

Protein Domains for GTSCR1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for GTSCR1 Gene

GenScript: Design optimal peptide antigens:
  • Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein (GTSC1_HUMAN)
genes like me logo Genes that share domains with GTSCR1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for GTSCR1 Gene

Function for GTSCR1 Gene

Phenotypes From GWAS Catalog for GTSCR1 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GTSCR1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GTSCR1 Gene

Localization for GTSCR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GTSCR1 Gene

Membrane. Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for GTSCR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GTSCR1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GTSCR1 Gene

Pathways & Interactions for GTSCR1 Gene

PathCards logo

SuperPathways for GTSCR1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GTSCR1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for GTSCR1 Gene

Drugs & Compounds for GTSCR1 Gene

No Compound Related Data Available

Transcripts for GTSCR1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for GTSCR1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000E60ADB_9606 lncRNA 695 2

HGNC: 18406,

RefSeq: NR_160904,

URS00007BFB79_9606 lncRNA 470 2

Ensembl: ENST00000582578 (view in UCSC) ,

LNCipedia: lnc-RTTN-8:1,

GTSCR1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for GTSCR1 Gene

1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GTSCR1

Alternative Splicing Database (ASD) splice patterns (SP) for GTSCR1 Gene

No ASD Table

Relevant External Links for GTSCR1 Gene

GeneLoc Exon Structure for
GTSCR1

Expression for GTSCR1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GTSCR1 Gene

mRNA differential expression in normal tissues according to GTEx for GTSCR1 Gene

This gene is overexpressed in Whole Blood (x21.0), Testis (x18.0), Small Intestine - Terminal Ileum (x7.0), and Liver (x4.4).

Protein differential expression in normal tissues from HIPED for GTSCR1 Gene

This gene is overexpressed in Esophagus (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GTSCR1 Gene



Protein tissue co-expression partners for GTSCR1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GTSCR1

genes like me logo Genes that share expression patterns with GTSCR1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GTSCR1 Gene

Orthologs for GTSCR1 Gene

Evolution for GTSCR1 Gene

ENSEMBL:
Gene Tree for GTSCR1 (if available)
TreeFam:
Gene Tree for GTSCR1 (if available)

No data available for Orthologs for GTSCR1 Gene

Paralogs for GTSCR1 Gene

No data available for Paralogs for GTSCR1 Gene

Variants for GTSCR1 Gene

Additional dbSNP identifiers (rs#s) for GTSCR1 Gene

Structural Variations from Database of Genomic Variants (DGV) for GTSCR1 Gene

Variant ID Type Subtype PubMed ID
esv32736 CNV gain+loss 17666407
esv34014 CNV loss 18971310
esv34035 CNV loss 18971310
esv3642988 CNV loss 21293372
esv3642989 CNV gain 21293372
esv3642990 CNV loss 21293372
esv3642993 CNV gain 21293372
nsv526953 CNV gain 19592680

Variation tolerance for GTSCR1 Gene

Gene Damage Index Score: 3.49; 55.18% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GTSCR1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GTSCR1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GTSCR1 Gene

Disorders for GTSCR1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for GTSCR1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
gilles de la tourette syndrome
  • gts
echolalia
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with GTSCR1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GTSCR1 Gene

Publications for GTSCR1 Gene

  1. Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype. (PMID: 12682296) State MW … Ward DC (Proceedings of the National Academy of Sciences of the United States of America 2003) 2 3 4
  2. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C … Lander ES (Nature 2005) 4

Products for GTSCR1 Gene

Sources for GTSCR1 Gene