Aliases for GSX2 Gene
External Ids for GSX2 Gene
Previous GeneCards Identifiers for GSX2 Gene
GeneCards Summary for GSX2 Gene
GSX2 (GS Homeobox 2) is a Protein Coding gene. Diseases associated with GSX2 include Diencephalic-Mesencephalic Junction Dysplasia Syndrome 2 and Diencephalic-Mesencephalic Junction Dysplasia. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is PDX1.
UniProtKB/Swiss-Prot Summary for GSX2 Gene
During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, necessary and sufficient to correctly specify the ventral lateral ganglionic eminence (LGE) and its major derivatives, the striatal projection neurons. At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (By similarity). Transcription factor that binds 5'-CNAATTAG-3' DNA sequence.