Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member i... See more...

Aliases for GSTP1 Gene

Aliases for GSTP1 Gene

  • Glutathione S-Transferase Pi 1 2 3 5
  • Glutathione S-Transferase P 3 4
  • GST Class-Pi 3 4
  • EC 2.5.1.18 4 51
  • GSTP1-1 3 4
  • FAEES3 3 4
  • GST3 3 4
  • GSTP 2 3
  • Fatty Acid Ethyl Ester Synthase III 3
  • Epididymis Secretory Protein Li 22 3
  • Deafness, X-Linked 7 3
  • HEL-S-22 3
  • GSTP1 5
  • DFN7 3
  • PI 3

External Ids for GSTP1 Gene

Previous HGNC Symbols for GSTP1 Gene

  • FAEES3
  • GST3

Previous GeneCards Identifiers for GSTP1 Gene

  • GC11P069874
  • GC11P069047
  • GC11P067601
  • GC11P067126
  • GC11P067107
  • GC11P067351
  • GC11P063681

Summaries for GSTP1 Gene

Entrez Gene Summary for GSTP1 Gene

  • Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

CIViC Summary for GSTP1 Gene

GeneCards Summary for GSTP1 Gene

GSTP1 (Glutathione S-Transferase Pi 1) is a Protein Coding gene. Diseases associated with GSTP1 include Barrett Esophagus and Oligoasthenoteratozoospermia. Among its related pathways are Neuroscience and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. Gene Ontology (GO) annotations related to this gene include glutathione transferase activity and kinase regulator activity. An important paralog of this gene is GSTA3.

UniProtKB/Swiss-Prot Summary for GSTP1 Gene

  • Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

Gene Wiki entry for GSTP1 Gene

PharmGKB "VIP" Summary for GSTP1 Gene

No data available for Tocris Summary , Rfam classification and piRNA Summary for GSTP1 Gene

Genomics for GSTP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GSTP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GSTP1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GSTP1

Top Transcription factor binding sites by QIAGEN in the GSTP1 gene promoter:
  • AP-1
  • c-Jun
  • MyoD
  • Nkx2-5
  • p53
  • Sp1

Genomic Locations for GSTP1 Gene

Genomic Locations for GSTP1 Gene
chr11:67,583,742-67,586,656
(GRCh38/hg38)
Size:
2,915 bases
Orientation:
Plus strand
chr11:67,351,066-67,354,131
(GRCh37/hg19)
Size:
3,066 bases
Orientation:
Plus strand

Genomic View for GSTP1 Gene

Genes around GSTP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GSTP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GSTP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GSTP1 Gene

Proteins for GSTP1 Gene

  • Protein details for GSTP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P09211-GSTP1_HUMAN
    Recommended name:
    Glutathione S-transferase P
    Protein Accession:
    P09211
    Secondary Accessions:
    • O00460
    • Q15690
    • Q5TZY3

    Protein attributes for GSTP1 Gene

    Size:
    210 amino acids
    Molecular mass:
    23356 Da
    Quaternary structure:
    • Homodimer. Interacts with CDK5.

    Three dimensional structures from OCA and Proteopedia for GSTP1 Gene

neXtProt entry for GSTP1 Gene

Selected DME Specific Peptides for GSTP1 Gene

P09211:
  • CLYGQLPKF
  • RMLLADQ
  • ISFADYNL
  • LLADQGQSWKEEV
  • FPLLSAYV
  • DGDLTLYQSN
  • NDGVEDLR
  • GLYGKDQ

Post-translational modifications for GSTP1 Gene

  • Ubiquitination at Lys45, Lys55, Lys121, Lys128, and Lys191
  • Modification sites at PhosphoSitePlus

Other Protein References for GSTP1 Gene

Antibody Products

Domains & Families for GSTP1 Gene

Gene Families for GSTP1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for GSTP1 Gene

InterPro:
Blocks:
  • Glutathione S-transferase, N-terminal
  • Alpha-class glutathione S-transferase signature
  • Pi-class glutathione S-transferase signature
ProtoNet:

Suggested Antigen Peptide Sequences for GSTP1 Gene

GenScript: Design optimal peptide antigens:
  • Glutathione S-transferase pi (B2C310_HUMAN)
  • Glutathione S-transferase pi (C7DJS1_HUMAN)
  • Glutathione S-transferase pi (C7DJS2_HUMAN)
  • GSTP1-1 (GSTP1_HUMAN)
  • Mutant GSTP1 (Q5D6A5_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P09211

UniProtKB/Swiss-Prot:

GSTP1_HUMAN :
  • Belongs to the GST superfamily. Pi family.
Family:
  • Belongs to the GST superfamily. Pi family.
genes like me logo Genes that share domains with GSTP1: view

Function for GSTP1 Gene

Molecular function for GSTP1 Gene

UniProtKB/Swiss-Prot Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; Evidence={ECO:0000269|PubMed:1540159, ECO:0000269|PubMed:1567427, ECO:0000269|PubMed:8433974};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=glutathione + prostaglandin J2 = prostaglandin J2-S-(R)-glutathione; Xref=Rhea:RHEA:50804, ChEBI:CHEBI:57925, ChEBI:CHEBI:133396, ChEBI:CHEBI:133771; Evidence={ECO:0000269|PubMed:9084911};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=glutathione + prostaglandin J2 = prostaglandin J2-S-(S)-glutathione; Xref=Rhea:RHEA:50808, ChEBI:CHEBI:57925, ChEBI:CHEBI:133396, ChEBI:CHEBI:133772; Evidence={ECO:0000269|PubMed:9084911};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=glutathione + prostaglandin A2 = prostaglandin A2-S-(S)-glutathione; Xref=Rhea:RHEA:50800, ChEBI:CHEBI:57925, ChEBI:CHEBI:133370, ChEBI:CHEBI:133769; Evidence={ECO:0000269|PubMed:9084911};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate; Xref=Rhea:RHEA:50260, ChEBI:CHEBI:57925, ChEBI:CHEBI:132200, ChEBI:CHEBI:132201; Evidence={ECO:0000269|PubMed:21046276};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=395 uM for prostaglandin A2 (at pH 7.0 and 37 degrees Celsius) {ECO:0000269|PubMed:9084911}; KM=201 uM for prostaglandin J2 (at pH 7.0 and 37 degrees Celsius) {ECO:0000269|PubMed:9084911}; Vmax=267 nmol/min/mg enzyme for the formation of the glutathione-S-conjugate of prostaglandin A2 (at pH 7.0 and 37 degrees Celsius) {ECO:0000269|PubMed:9084911}; Vmax=105 nmol/min/mg enzyme for the formation of the glutathione-S-conjugate of prostaglandin J2 (at pH 7.0 and 37 degrees Celsius) {ECO:0000269|PubMed:9084911};
GENATLAS Biochemistry:
glutathione S-transferase pi class,susceptibility factor in squamous-cell carcinoma of the esophagus and in Barrett's esophagus carcinoma,involved in the DNA methylation of cpG island in prostate cancer and other cancer

Enzyme Numbers (IUBMB) for GSTP1 Gene

Phenotypes From GWAS Catalog for GSTP1 Gene

Gene Ontology (GO) - Molecular Function for GSTP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004364 glutathione transferase activity IEA,IDA 1540159
GO:0004602 glutathione peroxidase activity IDA 16624487
GO:0005504 fatty acid binding IPI 16624487
GO:0005515 protein binding IEA,IPI 16636664
GO:0008144 drug binding IEA --
genes like me logo Genes that share ontologies with GSTP1: view
genes like me logo Genes that share phenotypes with GSTP1: view

Animal Models for GSTP1 Gene

MGI Knock Outs for GSTP1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTP1

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GSTP1 Gene

Localization for GSTP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GSTP1 Gene

Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GSTP1 gene
Compartment Confidence
mitochondrion 5
cytosol 5
plasma membrane 4
extracellular 4
nucleus 4
cytoskeleton 2
peroxisome 2
endoplasmic reticulum 2
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Mitochondria (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GSTP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space HDA 22664934
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm TAS 16130169
GO:0005739 mitochondrion IEA,IDA --
genes like me logo Genes that share ontologies with GSTP1: view

Pathways & Interactions for GSTP1 Gene

genes like me logo Genes that share pathways with GSTP1: view

SIGNOR curated interactions for GSTP1 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for GSTP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000302 response to reactive oxygen species ISS --
GO:0002674 negative regulation of acute inflammatory response NAS 18962899
GO:0006469 negative regulation of protein kinase activity IEA,IDA 16636664
GO:0006693 prostaglandin metabolic process IDA 9084911
GO:0006749 glutathione metabolic process IDA 1540159
genes like me logo Genes that share ontologies with GSTP1: view

Drugs & Compounds for GSTP1 Gene

(114) Drugs for GSTP1 Gene - From: DrugBank, PharmGKB, ClinicalTrials, ApexBio, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Vitamin E Approved, Vet_approved Nutra Enzyme, inhibitor 526,534
Cisplatin Approved Pharma Enzyme, substrate Inhibits DNA synthesis,chemotherapy drug, Potent pro-apoptotic anticancer agent; activates caspase-3, Platinum 3412
Etoposide Approved Pharma Enzyme, substrate Topo II inhibitor, Topoisomerase 2 Inhibitors 1461
Oxaliplatin Approved, Investigational Pharma Enzyme, substrate Antitumor agent, Platinum 1944
Clomipramine Approved, Investigational, Vet_approved Pharma Target, inhibitor 25

(233) Additional Compounds for GSTP1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(1E)-5-phenyl-1-(3-phenyloxiran-2-yl)pent-1-en-3-one
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene
(1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene
(1S,16R)-5,6,7,11-tetrahydroxy-8,8,10,12,16-pentamethyl-3-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadec-4-en-9-one

(2) ApexBio Compounds for GSTP1 Gene

Compound Action Cas Number
Ezatiostat (GST) P1-1 inhibitor 168682-53-9
Ezatiostat hydrochloride GST inhibitor 286942-97-0
genes like me logo Genes that share compounds with GSTP1: view

Transcripts for GSTP1 Gene

mRNA/cDNA for GSTP1 Gene

1 REFSEQ mRNAs :
16 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTP1

Alternative Splicing Database (ASD) splice patterns (SP) for GSTP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d
SP1: - -
SP2: - -
SP3: - - -
SP4: -
SP5:
SP6:

Relevant External Links for GSTP1 Gene

GeneLoc Exon Structure for
GSTP1

Expression for GSTP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GSTP1 Gene

mRNA differential expression in normal tissues according to GTEx for GSTP1 Gene

This gene is overexpressed in Esophagus - Mucosa (x5.9).

Protein differential expression in normal tissues from HIPED for GSTP1 Gene

This gene is overexpressed in Amniocyte (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GSTP1 Gene



Protein tissue co-expression partners for GSTP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GSTP1

SOURCE GeneReport for Unigene cluster for GSTP1 Gene:

Hs.523836

Evidence on tissue expression from TISSUES for GSTP1 Gene

  • Nervous system(4.9)
  • Blood(4.7)
  • Liver(4.7)
  • Intestine(4.7)
  • Eye(4.4)
  • Lung(4.4)
  • Pancreas(4)
  • Skin(3.8)
  • Muscle(3.5)
  • Stomach(3.5)
  • Kidney(3.4)
  • Lymph node(3.3)
  • Heart(3.3)
  • Thyroid gland(3.3)
  • Bone marrow(3.3)
  • Gall bladder(3)
  • Spleen(2.9)
  • Adrenal gland(2.9)
  • Urine(2.6)
genes like me logo Genes that share expression patterns with GSTP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GSTP1 Gene

Orthologs for GSTP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for GSTP1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia GSTP1 30 31
  • 99.68 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia GSTP1 30 31
  • 87.78 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia GSTP1 30 31
  • 86.83 (n)
OneToMany
-- 31
  • 85 (a)
OneToMany
-- 31
  • 84 (a)
OneToMany
-- 31
  • 79 (a)
OneToMany
-- 31
  • 76 (a)
OneToMany
-- 31
  • 75 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Gstp2 17 31
  • 84 (a)
OneToMany
Gstp1 30 17 31
  • 83.49 (n)
OneToMany
BC021614 31
  • 70 (a)
OneToMany
Gstp-ps 17
Rat
(Rattus norvegicus)
Mammalia Gstp1 30
  • 82.7 (n)
Oppossum
(Monodelphis domestica)
Mammalia GSTP1 31
  • 64 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia GSTP1 31
  • 67 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia gstp1 30
  • 57.26 (n)
Zebrafish
(Danio rerio)
Actinopterygii gstp1 30 31
  • 63.14 (n)
OneToMany
gstp2 31
  • 59 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea gst-1 31 32
  • 39 (a)
ManyToMany
gst-23 31
  • 38 (a)
ManyToMany
gst-25 31
  • 35 (a)
ManyToMany
Species where no ortholog for GSTP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for GSTP1 Gene

ENSEMBL:
Gene Tree for GSTP1 (if available)
TreeFam:
Gene Tree for GSTP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GSTP1: view image

Paralogs for GSTP1 Gene

Paralogs for GSTP1 Gene

(8) SIMAP similar genes for GSTP1 Gene using alignment to 6 proteins:

  • GSTP1_HUMAN
  • A8MX94_HUMAN
  • B2C310_HUMAN
  • C7DJS1_HUMAN
  • C7DJS2_HUMAN
  • Q5D6A5_HUMAN

Pseudogenes.org Pseudogenes for GSTP1 Gene

genes like me logo Genes that share paralogs with GSTP1: view

Variants for GSTP1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GSTP1 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
747436 Likely Benign: not provided 67,586,463(+) G/A SYNONYMOUS_VARIANT
rs1555022268 Likely Pathogenic: Kala-azar susceptibility 2 67,585,320(+) TC/CA INTRON_VARIANT
rs1695 Drug Response: Neoplasm of the large intestine; cyclophosphamide and epirubicin response - Efficacy, Toxicity/ADR; fluorouracil and oxaliplatin response - Efficacy; cisplatin response - Toxicity/ADR; Platinum compounds response - Toxicity/ADR. - 67,585,218(+) A/Gp.Ile105Val MISSENSE_VARIANT
rs1138272 - p.Ala114Val
rs41462048 - p.Gly169Asp

Additional dbSNP identifiers (rs#s) for GSTP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for GSTP1 Gene

Variant ID Type Subtype PubMed ID
dgv1214n100 CNV gain 25217958
dgv1981n54 CNV gain 21841781
esv2422195 CNV duplication 17116639
nsv468606 CNV gain 19166990

Variation tolerance for GSTP1 Gene

Residual Variation Intolerance Score: 59.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.95; 74.56% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GSTP1 Gene

Human Gene Mutation Database (HGMD)
GSTP1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GSTP1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSTP1 Gene

Disorders for GSTP1 Gene

MalaCards: The human disease database

(59) MalaCards diseases for GSTP1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
barrett esophagus
  • barrett metaplasia
oligoasthenoteratozoospermia
  • oat
deafness, x-linked 7
  • dfnx7
oral mucosa leukoplakia
  • leukoplakia, oral
squamous cell carcinoma
  • epidermoid carcinoma
- elite association - COSMIC cancer census association via MalaCards
Search GSTP1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GSTP1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with GSTP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GSTP1 Gene

Publications for GSTP1 Gene

  1. Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. (PMID: 19424794) MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk (Breast cancer research and treatment 2010) 3 23 41
  2. [Role of polymorphic markers of antioxidants (NQO1, GSTP1, GPX1) genes in adaptive response to hazardous work conditions in workers]. (PMID: 20480816) Kochetova OV … Viktorova TV (Meditsina truda i promyshlennaia ekologiia 2010) 3 23 41
  3. Genetic polymorphisms in GSTA1, GSTP1, GSTT1, and GSTM1 and gastric cancer risk in a Vietnamese population. (PMID: 20377137) Nguyen TV … Jansent JB (Oncology research 2010) 3 23 41
  4. Glutathione S-transferase gene polymorphisms and air pollution as interactive risk factors for asthma in a multicentre Italian field study: A preliminary study. (PMID: 20367187) Piacentini S … Fuciarelli M (Annals of human biology 2010) 3 23 41
  5. Glutathione S-Transferase P1 (GSTP1) gene polymorphism increases age-related susceptibility to hepatocellular carcinoma. (PMID: 20331903) Chen YL … Tsai HT (BMC medical genetics 2010) 3 23 41

Products for GSTP1 Gene

Sources for GSTP1 Gene