Aliases for GSTO2 Gene
External Ids for GSTO2 Gene
Previous GeneCards Identifiers for GSTO2 Gene
The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
GeneCards Summary for GSTO2 Gene
GSTO2 (Glutathione S-Transferase Omega 2) is a Protein Coding gene. Diseases associated with GSTO2 include Barrett's Adenocarcinoma and Skin Carcinoma. Among its related pathways are Drug metabolism - cytochrome P450 and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and protein disulfide oxidoreductase activity. An important paralog of this gene is GSTO1.
UniProtKB/Swiss-Prot Summary for GSTO2 Gene
Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).