GSTM5 Gene (Protein Coding)

Glutathione S-Transferase Mu 5

GC01P109711
GIFtS:
41
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enz... See more...

Aliases for GSTM5 Gene

Aliases for GSTM5 Gene

  • Glutathione S-Transferase Mu 5 2 3 3 4 5
  • Glutathione S-Transferase M5 2 3
  • GST Class-Mu 5 3 4
  • EC 2.5.1.18 4 51
  • GSTM5-5 3 4
  • Epididymis Secretory Sperm Binding Protein 3
  • S-(Hydroxyalkyl)Glutathione Lyase M5 3
  • Glutathione S-Aralkyltransferase M5 3
  • Glutathione S-Alkyltransferase M5 3
  • Glutathione S-Aryltransferase M5 3
  • GSTM5 5
  • GTM5 3

External Ids for GSTM5 Gene

Previous GeneCards Identifiers for GSTM5 Gene

  • GC01P110733
  • GC01P109184
  • GC01P109356
  • GC01P109553
  • GC01P109966
  • GC01P110056
  • GC01P110255
  • GC01P108124
  • GC01P110256

Summaries for GSTM5 Gene

Entrez Gene Summary for GSTM5 Gene

  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]

GeneCards Summary for GSTM5 Gene

GSTM5 (Glutathione S-Transferase Mu 5) is a Protein Coding gene. Diseases associated with GSTM5 include Borderline Glaucoma and Barrett's Adenocarcinoma. Among its related pathways are Drug metabolism - cytochrome P450 and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include glutathione transferase activity. An important paralog of this gene is GSTM1.

UniProtKB/Swiss-Prot Summary for GSTM5 Gene

  • Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Additional gene information for GSTM5 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GSTM5 Gene

Genomics for GSTM5 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for GSTM5 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J109711 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE CraniofacialAtlas 623.9 +0.6 573 1.5 SCRT2 POLR2A GSTM5 GSTM3 GSTM1 SORT1 ENSG00000241720
GH01J109709 Enhancer 0.2 dbSUPER 625.4 -1.6 -1554 1.4 GSTM5 GSTM3 GSTM4 piR-46847-014 GSTM1 GSTM2
GH01J109718 Enhancer 1.2 Ensembl ENCODE dbSUPER 20.5 +7.6 7649 1.6 CREB1 LEF1 BACH1 JUND MTA2 MTA1 REST NR2C1 ZNF24 ZNF740 GSTM5 EPS8L3 AMIGO1 GPR61 ENSG00000254942 CSF1 UBL4B CYB561D1 ENSG00000241720 GSTM3
GH01J109482 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 10.6 -227.6 -227637 2.6 ZNF221 ARHGAP35 SP1 CREB1 GATAD2A CTCF HNRNPL YBX1 PRDM10 ZNF629 ATXN7L2 ENSG00000258634 ENSG00000244716 PRPF38B STRIP1 SYPL2 CLCC1 RBM15 ENSG00000228665 ENSG00000273373
GH01J109725 Enhancer 1.2 Ensembl ENCODE dbSUPER 18.6 +14.3 14256 1.6 LEF1 JUND FOXA1 MTA2 ZNF24 MTA1 DPF2 HDAC1 SOX6 TCF12 ENSG00000241720 GSTM3 GSTM5 EPS8L3 ENSG00000228703 AMPD2 AHCYL1 GPR61 ENSG00000225113 RNU6V
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GSTM5 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GSTM5

Top Transcription factor binding sites by QIAGEN in the GSTM5 gene promoter:
  • AML1a
  • AP-1
  • ARP-1
  • Chx10
  • HOXA3
  • LyF-1
  • Pax-2
  • Pax-2a
  • Pax-2b

Genomic Locations for GSTM5 Gene

Genomic Locations for GSTM5 Gene
chr1:109,711,751-109,775,428
(GRCh38/hg38)
Size:
63,678 bases
Orientation:
Plus strand
chr1:110,254,864-110,318,050
(GRCh37/hg19)
Size:
63,187 bases
Orientation:
Plus strand

Genomic View for GSTM5 Gene

Genes around GSTM5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GSTM5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GSTM5 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for GSTM5 Gene

Proteins for GSTM5 Gene

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  • Protein details for GSTM5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P46439-GSTM5_HUMAN
    Recommended name:
    Glutathione S-transferase Mu 5
    Protein Accession:
    P46439
    Secondary Accessions:
    • A8K0V8
    • Q6PD78

    Protein attributes for GSTM5 Gene

    Size:
    218 amino acids
    Molecular mass:
    25675 Da
    Quaternary structure:
    • Homodimer.

neXtProt entry for GSTM5 Gene

Protein Expression for GSTM5 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Selected DME Specific Peptides for GSTM5 Gene

P46439:
  • WLNEKFK
  • KISAYMK
  • IRLLLEYT
  • TEEEKIRVDI
  • TQSNAILRY
  • FLGKRPWF
  • RFEGLKKIS
  • IRVDILENQ
  • LGYWDIRG
  • APDYDRSQWL
  • LDFPNLPYL
  • VDFLAYD
  • CGETEEE
  • KITQSNAI
  • NLKDFISRFEGL

Post-translational modifications for GSTM5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GSTM5 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for GSTM5 Gene

Gene Families for GSTM5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for GSTM5 Gene

InterPro:
Blocks:
  • Glutathione S-transferase, N-terminal
  • Mu-class glutathione S-transferase signature
ProtoNet:

Suggested Antigen Peptide Sequences for GSTM5 Gene

GenScript: Design optimal peptide antigens:
  • GSTM5-5 (GSTM5_HUMAN)
  • cDNA, FLJ96269, Homo sapiens glutathione S-transferase M5 (GSTM5), mRNA (Q5T8R2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P46439

UniProtKB/Swiss-Prot:

GSTM5_HUMAN :
  • Belongs to the GST superfamily. Mu family.
Family:
  • Belongs to the GST superfamily. Mu family.
genes like me logo Genes that share domains with GSTM5: view

Function for GSTM5 Gene

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Molecular function for GSTM5 Gene

UniProtKB/Swiss-Prot Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; Evidence={ECO:0000269|PubMed:10587441};.
GENATLAS Biochemistry:
glutathione-S-transferase 5,mu class

Enzyme Numbers (IUBMB) for GSTM5 Gene

Phenotypes From GWAS Catalog for GSTM5 Gene

Gene Ontology (GO) - Molecular Function for GSTM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004364 glutathione transferase activity IEA,IDA 10587441
GO:0005515 protein binding IEA,IPI 25416956
GO:0016740 transferase activity IEA --
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with GSTM5: view
genes like me logo Genes that share phenotypes with GSTM5: view

Animal Models for GSTM5 Gene

MGI Knock Outs for GSTM5:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTM5

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GSTM5 Gene

Localization for GSTM5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GSTM5 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GSTM5 gene
Compartment Confidence
cytosol 5
extracellular 4
mitochondrion 2
plasma membrane 1
cytoskeleton 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytokinetic bridge (2)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GSTM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA,TAS --
GO:0045171 intercellular bridge IDA --
genes like me logo Genes that share ontologies with GSTM5: view

Pathways & Interactions for GSTM5 Gene

genes like me logo Genes that share pathways with GSTM5: view

Pathways by source for GSTM5 Gene

1 GeneGo (Thomson Reuters) pathway for GSTM5 Gene
  • Glutathione metabolism

Gene Ontology (GO) - Biological Process for GSTM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006749 glutathione metabolic process IDA 10587441
GO:1901687 glutathione derivative biosynthetic process TAS --
genes like me logo Genes that share ontologies with GSTM5: view

No data available for SIGNOR curated interactions for GSTM5 Gene

Drugs & Compounds for GSTM5 Gene

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(6) Drugs for GSTM5 Gene - From: DrugBank and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Glutathione Approved, Investigational Nutra Target 0
Oxidized glutathione Approved, Experimental, Investigational Pharma Target, activator 0
Trichloroethylene Approved Pharma 0
Water Approved Pharma 0
Hydrochloric acid Experimental Pharma 0

(37) Additional Compounds for GSTM5 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene
(1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene
(1S,2R)-Naphthalene 1,2-oxide
  • (1S,2R)-Naphthalene epoxide
1,1-Dichloroethylene epoxide
  • 2,2-Dichlorooxirane
genes like me logo Genes that share compounds with GSTM5: view

Transcripts for GSTM5 Gene

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mRNA/cDNA for GSTM5 Gene

1 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTM5

Alternative Splicing Database (ASD) splice patterns (SP) for GSTM5 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2:
SP3: -

Relevant External Links for GSTM5 Gene

GeneLoc Exon Structure for
GSTM5

Expression for GSTM5 Gene

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  1. Primer
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mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GSTM5 Gene

mRNA expression in normal human tissues for GSTM5 Gene
mRNA expression by BioGPS for GSTM5 GenemRNA expression by GTEx for GSTM5 Gene

mRNA differential expression in normal tissues according to GTEx for GSTM5 Gene

This gene is overexpressed in Ovary (x6.5).

Protein differential expression in normal tissues from HIPED for GSTM5 Gene

This gene is overexpressed in Ovary (20.5), Skin (16.1), and Brain (11.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GSTM5 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GSTM5

SOURCE GeneReport for Unigene cluster for GSTM5 Gene:

Hs.75652

Evidence on tissue expression from TISSUES for GSTM5 Gene

  • Nervous system(4.6)
  • Muscle(2.6)
  • Liver(2.3)
  • Eye(2.1)
  • Kidney(2.1)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with GSTM5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GSTM5 Gene

Orthologs for GSTM5 Gene

This gene was present in the common ancestor of animals.

Orthologs for GSTM5 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia GSTM5 30 31
  • 98.93 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Gstm1 30
  • 81.65 (n)
Mouse
(Mus musculus)
 Mammalia Gstm2 31
  • 81 (a)
 ManyToMany
Gstm7 31
  • 81 (a)
 ManyToMany
Gstm1 30 17 31
  • 80.73 (n)
 ManyToMany
Gstm4 31
  • 79 (a)
 ManyToMany
Gm6665 31
  • 78 (a)
 ManyToMany
Gstm3 31
  • 75 (a)
 ManyToMany
Gstm6 31
  • 74 (a)
 ManyToMany
Gm4845 31
  • 74 (a)
 ManyToMany
Cow
(Bos Taurus)
 Mammalia GSTM2 31
  • 81 (a)
 ManyToMany
GSTM4 31
  • 81 (a)
 ManyToMany
GSTM1 31 31
  • 79 (a)
 ManyToMany
-- 31
  • 74 (a)
 ManyToMany
Dog
(Canis familiaris)
 Mammalia -- 31
  • 76 (a)
 OneToMany
Lizard
(Anolis carolinensis)
 Reptilia -- 31
  • 71 (a)
 ManyToMany
-- 31
  • 69 (a)
 ManyToMany
-- 31
  • 67 (a)
 ManyToMany
Zebrafish
(Danio rerio)
 Actinopterygii zgc:173994 31
  • 63 (a)
 ManyToMany
gstm 31
  • 63 (a)
 ManyToMany
gstm3 31
  • 61 (a)
 ManyToMany
Worm
(Caenorhabditis elegans)
 Secernentea gst-1 31
  • 30 (a)
 ManyToMany
gst-23 31
  • 29 (a)
 ManyToMany
gst-25 31
  • 28 (a)
 ManyToMany
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 41 (a)
 ManyToMany
-- 31
  • 41 (a)
 ManyToMany
-- 31
  • 39 (a)
 ManyToMany
-- 31
  • 28 (a)
 ManyToMany
Species where no ortholog for GSTM5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for GSTM5 Gene

ENSEMBL:
Gene Tree for GSTM5 (if available)
TreeFam:
Gene Tree for GSTM5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GSTM5: view image

Paralogs for GSTM5 Gene

Paralogs for GSTM5 Gene

(6) SIMAP similar genes for GSTM5 Gene using alignment to 4 proteins:

  • GSTM5_HUMAN
  • Q5T8Q9_HUMAN
  • Q5T8R1_HUMAN
  • Q5T8R2_HUMAN

Pseudogenes.org Pseudogenes for GSTM5 Gene

genes like me logo Genes that share paralogs with GSTM5: view

Variants for GSTM5 Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GSTM5 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
708302 Likely Benign: not provided 109,715,232(+) C/T MISSENSE_VARIANT
713558 Benign: not provided 109,717,418(+) A/G MISSENSE_VARIANT
769521 Benign: not provided 109,715,019(+) C/T MISSENSE_VARIANT
779857 Benign: not provided 109,715,192(+) G/C MISSENSE_VARIANT
784446 Benign: not provided 109,713,540(+) C/G SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for GSTM5 Gene

Structural Variations from Database of Genomic Variants (DGV) for GSTM5 Gene

Variant ID Type Subtype PubMed ID
dgv265n100 CNV gain 25217958
dgv270n100 CNV gain 25217958
dgv273n100 CNV loss 25217958
dgv276n100 CNV loss 25217958
dgv500n54 CNV gain 21841781
dgv501n54 CNV gain 21841781
dgv502n54 CNV gain 21841781
esv1003982 CNV deletion 20482838
esv25172 CNV gain+loss 19812545
nsv1001758 CNV gain 25217958
nsv1003510 CNV loss 25217958
nsv1003914 CNV gain 25217958
nsv1007399 CNV loss 25217958
nsv10617 CNV gain 18304495
nsv2310 CNV deletion 18451855
nsv2332 CNV insertion 18451855
nsv547487 CNV gain 21841781
nsv547491 CNV gain 21841781
nsv547495 CNV gain+loss 21841781
nsv946134 CNV duplication 23825009

Variation tolerance for GSTM5 Gene

Residual Variation Intolerance Score: 87.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.62; 65.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GSTM5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GSTM5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSTM5 Gene

Disorders for GSTM5 Gene

MalaCards: The human disease database

(3) MalaCards diseases for GSTM5 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
borderline glaucoma
  • preglaucoma
barrett's adenocarcinoma
  • adenocarcinoma arising in barrett's mucosa
type 1 diabetes mellitus 3
  • diabetes mellitus, insulin-dependent, 3
- elite association - COSMIC cancer census association via MalaCards
Search GSTM5 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GSTM5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with GSTM5: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GSTM5 Gene

Publications for GSTM5 Gene

  1. A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5. (PMID: 8473333) Takahashi Y … Listowsky I (The Journal of biological chemistry 1993) 2 3 4
  2. Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1. (PMID: 19856098) Yu KD … Shao ZM (Breast cancer research and treatment 2010) 3 41
  3. Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. (PMID: 20200426) Moyer AM … Weinshilboum RM (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
  4. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer. (PMID: 20819778) Zhang X … Wu X (Carcinogenesis 2010) 3 41
  5. Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PMID: 20485444) Wang Y … Huang W (Journal of human genetics 2010) 3 41

ExternalLinks

View latest publications for GSTM5 gene in Mastermind

Products for GSTM5 Gene

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Sources for GSTM5 Gene