Aliases for GSTK1 Gene
External Ids for GSTK1 Gene
Previous GeneCards Identifiers for GSTK1 Gene
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
GeneCards Summary for GSTK1 Gene
GSTK1 (Glutathione S-Transferase Kappa 1) is a Protein Coding gene. Among its related pathways are Drug metabolism - cytochrome P450 and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and glutathione transferase activity.
UniProtKB/Swiss-Prot for GSTK1 Gene
Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).