Free for academic non-profit institutions. Other users need a Commercial license
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorph... See more...
Aliases for GSTA2 Gene
Aliases for GSTA2 Gene
External Ids for GSTA2 Gene
- HGNC: 4627
- NCBI Entrez Gene: 2939
- Ensembl: ENSG00000244067
- OMIM®: 138360
- UniProtKB/Swiss-Prot: P09210
Previous HGNC Symbols for GSTA2 Gene
- GST2
Previous GeneCards Identifiers for GSTA2 Gene
- GC06M052617
- GC06M052662
- GC06M052723
- GC06M052614
- GC06M052446
Summaries for GSTA2 Gene
-
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
GeneCards Summary for GSTA2 Gene
GSTA2 (Glutathione S-Transferase Alpha 2) is a Protein Coding gene. Diseases associated with GSTA2 include Periventricular Nodular Heterotopia. Among its related pathways are Naphthalene metabolism and Drug metabolism - cytochrome P450. Gene Ontology (GO) annotations related to this gene include glutathione transferase activity. An important paralog of this gene is GSTA1.
UniProtKB/Swiss-Prot Summary for GSTA2 Gene
-
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Additional gene information for GSTA2 Gene
- HGNC (4627)
- NCBI Entrez Gene (2939)
- Ensembl (ENSG00000244067)
- OMIM® (138360)
- UniProtKB/Swiss-Prot (P09210)
- Open Targets Platform(ENSG00000244067)
- Alliance of Genome Resources
- Search for GSTA2 at DataMed
- Search for GSTA2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GSTA2 Gene
Genomics for GSTA2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GSTA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GSTA2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GSTA2
- Top Transcription factor binding sites by QIAGEN in the GSTA2 gene promoter:
-
- C/EBPalpha
- FOXD1
- FOXD3
- HFH-1
- HNF-1
- HNF-1A
- HNF-3beta
- Pbx1a
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for GSTA2 Gene
Latest Assembly
- chr6:52,750,087-52,763,475
- (GRCh38/hg38)
- Size:
- 13,389 bases
- Orientation:
- Minus strand
Previous Assembly
- chr6:52,614,885-52,628,273
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 13,389 bases
- Orientation:
- Minus strand
Genomic View for GSTA2 Gene
Genes around GSTA2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p12.2 by HGNC
- 6p12.2 by Entrez Gene
- 6p12.2 by Ensembl
GSTA2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GSTA2 Gene
Proteins for GSTA2 Gene
-
Protein details for GSTA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09210-GSTA2_HUMAN
- Recommended name:
- Glutathione S-transferase A2
- Protein Accession:
- P09210
- Q12759
- Q16491
- Q9NTY6
Protein attributes for GSTA2 Gene
- Size:
- 222 amino acids
- Molecular mass:
- 25664 Da
- Quaternary structure:
-
- Homodimer or heterodimer of GSTA1 and GSTA2.
Protein Expression for GSTA2 Gene
Selected DME Specific Peptides for GSTA2 Gene
- P09210:
-
- QTRAILNYIA
- RYFPAFE
- KYNLYGKD
- AAGVEFE
- AGVEFEE
- PAFEKVLKSH
- SNLPTVKKFLQPGS
- LAAAGVEF
- QVPMVEIDGMKL
- LVGNKLS
- SHGQDYLVGN
Post-translational modifications for GSTA2 Gene
Other Protein References for GSTA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences GSTA2 Antibody (LS-B11008) and GSTA2 Antibody (LS-B14901)
-
Custom Antibody ServicesOriGene Antibodies for GSTA2
- Novus Biologicals Antibodies for GSTA2
-
Abcam antibodies for GSTA2
- Invitrogen Antibodies for GSTA2 (AFLGC-Gsta2)
-
Boster Bio Antibodies for GSTA2
-
Custom Antibody ServicesProSci Antibodies for GSTA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for GSTA2
Protein products for research
-
OriGene Purified Proteins for GSTA2
- Search Origene for MassSpec and Protein Over-expression Lysates for GSTA2
- Origene Custom Protein Services for GSTA2
- antibodies-online: Show 12 available GSTa2 Proteins ranked by validation data
- Compare Top GSTa2 Proteins
-
Quality Products:
-
Abcam proteins for GSTA2
Assay products for research
- G Biosciences Immunotag™ Glutathione S-transferase A2 ELISA Kit
- antibodies-online: Show 16 available GSTa2 Elisa Kits ranked by validation data
- Compare Top GSTa2 Elisa Kits
-
Quality Products:
-
Abcam assays for GSTA2
Domains & Families for GSTA2 Gene
Gene Families for GSTA2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for GSTA2 Gene
- InterPro:
- Blocks:
-
- Glutathione S-transferase, N-terminal
- Alpha-class glutathione S-transferase signature
Suggested Antigen Peptide Sequences for GSTA2 Gene
- GenScript: Design optimal peptide antigens:
-
- GTH2 (GSTA2_HUMAN)
- Glutathione S-transferase (Q16605_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P09210- Family:
-
- Belongs to the GST superfamily. Alpha family.
Function for GSTA2 Gene
Molecular function for GSTA2 Gene
- UniProtKB/Swiss-Prot Function:
- Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18;.
- GENATLAS Biochemistry:
- glutathione S-transferase 2,alpha,expressed in liver,with a proximal promoter essential for the binding of activating transcription factor complexes
Enzyme Numbers (IUBMB) for GSTA2 Gene
Phenotypes From GWAS Catalog for GSTA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004364 | glutathione transferase activity | TAS,ISS | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for GSTA2 Gene
Animal Models for research
-
Taconic Biosciences Mouse Models for GSTA2
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GSTA2 - Starting at $85 >
- * GSTA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GSTA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSTA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSTA2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSTA2
- Browse OriGene Inhibitory RNA Products For GSTA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTA2
Clone products for research
- Applied Biological Materials (abm): Clones for GSTA2 - Starting at $45 >
- * GSTA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GSTA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSTA2
Cell Lines for research
-
Horizon Cell Lines for GSTA2
No data available for Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GSTA2 Gene
Localization for GSTA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GSTA2 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| extracellular | 4 |
| mitochondrion | 2 |
| nucleus | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0070062 | extracellular exosome | TAS | -- |
Pathways & Interactions for GSTA2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Drug metabolism - cytochrome P450 | ||
| 2 | Glutathione metabolism |
Glutathione metabolism
.60
|
|
| 3 | Metabolism |
.40
|
|
| 4 | Cytochrome P450 - arranged by substrate type | ||
| 5 | Fluid shear stress and atherosclerosis | ||
Pathways by source for GSTA2 Gene
4 BioSystems pathways for GSTA2 Gene
4 Reactome pathways for GSTA2 Gene
1 PharmGKB pathway for GSTA2 Gene
10 KEGG pathways for GSTA2 Gene
4 GeneGo (Thomson Reuters) pathways for GSTA2 Gene
- 2-Naphthylamine and 2-Nitronaphtalene metabolism
- Dichloroethylene metabolism
- Glutathione metabolism
- Naphthalene metabolism
Interacting Proteins for GSTA2 Gene
Selected Interacting proteins:
P09210-GSTA2_HUMAN
ENSP00000420168
for GSTA2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for GSTA2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006749 | glutathione metabolic process | ISS | -- |
| GO:0006805 | xenobiotic metabolic process | IBA | 21873635 |
| GO:0030855 | epithelial cell differentiation | IEP | 21492153 |
| GO:0035722 | interleukin-12-mediated signaling pathway | TAS | -- |
| GO:1901687 | glutathione derivative biosynthetic process | TAS | -- |
No data available for SIGNOR curated interactions for GSTA2 Gene
Drugs & Compounds for GSTA2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Busulfan | Approved, Investigational | Pharma | Enzyme, substrate | 636 | ||
| chloroquine | Approved, Investigational, Vet_approved | Pharma | Target, inhibitor | 224 | ||
| Clofibrate | Approved, Investigational | Pharma | Enzyme, inhibitor | 2 | ||
| Ethacrynic acid | Approved, Investigational | Pharma | Enzyme, inhibitor | 5 | ||
| Glutathione | Approved, Investigational | Nutra | Target, Enzyme, substrate | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene |
|
|
||||
| (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene |
|
|
||||
| (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene |
|
|
||||
| (1S,2R)-Naphthalene 1,2-oxide |
|
|
||||
| 1,1-Dichloroethylene epoxide |
|
|
(1) ApexBio Compounds for GSTA2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Ezatiostat hydrochloride | GST inhibitor | 286942-97-0 |
Transcripts for GSTA2 Gene
mRNA/cDNA for GSTA2 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000493422 1221 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GSTA2 - Starting at $85 >
- * GSTA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GSTA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSTA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSTA2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSTA2
- Browse OriGene Inhibitory RNA Products For GSTA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTA2
Clone products for research
- Applied Biological Materials (abm): Clones for GSTA2 - Starting at $45 >
- * GSTA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GSTA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSTA2
Relevant External Links for GSTA2 Gene
- GeneLoc Exon Structure for
- GSTA2
Expression for GSTA2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for GSTA2 Gene
This gene is overexpressed in Liver (x18.1), Pancreas (x15.8), and Kidney - Cortex (x10.3).
This gene is overexpressed in Pancreas (24.6), Liver (19.5), and Gallbladder (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GSTA2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GSTA2
SOURCE GeneReport for Unigene cluster for GSTA2 Gene:
Hs.94107mRNA Expression by UniProt/SwissProt for GSTA2 Gene:
P09210-GSTA2_HUMAN
Tissue specificity:
Liver.
Evidence on tissue expression from TISSUES for GSTA2 Gene
- Liver(4.8)
- Lung(4.4)
- Blood(4.3)
- Kidney(3.7)
- Intestine(2.8)
- Stomach(2.6)
- Pancreas(2.5)
Primer products for research
-
OriGene qPCR primer pairs for GSTA2
-
OriGene qPCR primer pairs and template standards for GSTA2
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GSTA2 Gene
Orthologs for GSTA2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GSTA2 29 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC501110 29 |
|
||
| Cow (Bos Taurus) |
Mammalia | GSTA5 30 |
|
ManyToMany | |
| Mouse (Mus musculus) |
Mammalia | Gm10639 30 |
|
ManyToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 30 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 30 |
|
ManyToMany | |
| Dog (Canis familiaris) |
Mammalia | -- 30 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | GSTA 29 |
|
||
| -- 30 |
|
ManyToMany | |||
| GSTA3 30 |
|
ManyToMany | |||
| Lizard (Anolis carolinensis) |
Reptilia | -- 30 |
|
ManyToMany | |
| -- 30 |
|
ManyToMany | |||
| -- 30 |
|
ManyToMany | |||
| -- 30 |
|
ManyToMany | |||
| Zebrafish (Danio rerio) |
Actinopterygii | gstal 30 |
|
ManyToMany | |
| zgc:173962 30 |
|
ManyToMany | |||
| zgc:173961 30 |
|
ManyToMany | |||
| Worm (Caenorhabditis elegans) |
Secernentea | gst-41 30 |
|
ManyToMany | |
| F56A4.3 30 |
|
ManyToMany | |||
| gst-10 30 |
|
ManyToMany | |||
| Y45G12C.3 30 |
|
ManyToMany | |||
| F56A4.4 30 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToMany |
- Species where no ortholog for GSTA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for GSTA2 Gene
- ENSEMBL:
- Gene Tree for GSTA2 (if available)
- TreeFam:
- Gene Tree for GSTA2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GSTA2: view image
- Alliance of Genome Resources:
- Additional Orthologs for GSTA2
Paralogs for GSTA2 Gene
Variants for GSTA2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv10661n54 | CNV | loss | 21841781 |
| dgv1182e214 | CNV | gain | 21293372 |
| dgv1772e212 | CNV | loss | 25503493 |
| dgv5961n100 | CNV | loss | 25217958 |
| dgv5962n100 | CNV | loss | 25217958 |
| esv2436160 | CNV | deletion | 19546169 |
| esv2666271 | CNV | deletion | 23128226 |
| esv2732085 | CNV | deletion | 23290073 |
| esv2752126 | CNV | gain | 17911159 |
| esv2759429 | CNV | loss | 17122850 |
| esv2763990 | CNV | loss | 21179565 |
| esv3609003 | CNV | loss | 21293372 |
| esv3609004 | CNV | loss | 21293372 |
| esv3609005 | CNV | loss | 21293372 |
| esv4858 | OTHER | sequence alteration | 18987735 |
| esv9378 | CNV | loss | 19470904 |
| nsv1020575 | CNV | loss | 25217958 |
| nsv1020891 | CNV | loss | 25217958 |
| nsv1023506 | CNV | gain | 25217958 |
| nsv1023696 | CNV | loss | 25217958 |
| nsv462945 | CNV | loss | 19166990 |
| nsv470818 | CNV | loss | 18288195 |
| nsv523124 | CNV | loss | 19592680 |
| nsv603106 | CNV | loss | 21841781 |
| nsv970121 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
74.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.29;
53.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GSTA2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSTA2 Gene
Disorders for GSTA2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| periventricular nodular heterotopia |
|
|
Search GSTA2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GSTA2
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GSTA2 Gene
Publications for GSTA2 Gene
- No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk. (PMID: 19859803) Andonova IE … Brauch H (Breast cancer research and treatment 2010) 3 22 40
- The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population. (PMID: 19639209) Silva SN … Gaspar JF (Oncology reports 2009) 3 22 40
- Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma. (PMID: 17290392) Landi S … Puntoni R (International journal of cancer 2007) 3 22 40
- A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. (PMID: 16006997) Landi S … Bellvitge Colorectal Cancer Study Group (Pharmacogenetics and genomics 2005) 3 22 40
- Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form. (PMID: 15128049) Ning B … Coles B (Pharmacogenetics 2004) 3 22 40
ExternalLinks
Products for GSTA2 Gene
- Custom Antibody ServicesOriGene Antibodies for GSTA2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for GSTA2
- Search Origene for MassSpec and Protein Over-expression Lysates for GSTA2
- Origene Custom Protein Services for GSTA2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSTA2
- Browse OriGene Inhibitory RNA Products For GSTA2
- OriGene qPCR primer pairs for GSTA2
- OriGene qPCR primer pairs and template standards for GSTA2
- OriGene CRISPR knockouts for GSTA2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For GSTA2
- Sino Biological Human cDNA Clone for GSTA2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for GSTA2
- Novus Biologicals proteins and lysates for GSTA2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for GSTA2
- Abcam proteins for GSTA2
- Abcam assays for GSTA2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for GSTA2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for GSTA2 (AFLGC-Gsta2)
- ApexBio compounds for GSTA2
- VectorBuilder Custom and pre-made DNA vectors for GSTA2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GSTA2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GSTA2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GSTA2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GSTA2
- antibodies-online: Show 110 available GSTa2 Antibodies ranked by validation data
- Compare Top GSTa2 Antibodies
- antibodies-online: Show 16 available GSTa2 Elisa Kits ranked by validation data
- Compare Top GSTa2 Elisa Kits
- Quality Products:
- antibodies-online: Show 12 available GSTa2 Proteins ranked by validation data
- Compare Top GSTa2 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for GSTA2
- Search Santa Cruz Biotechnology (SCBT) for GSTA2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GSTA2
- Custom Antibody ServicesProSci Antibodies for GSTA2
- Search for GSTA2 Proteins at ProSci
- Horizon Cell Lines for GSTA2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSTA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSTA2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GSTA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSTA2
- Boster Bio Antibodies for GSTA2
- Browse Boster Bio ELISA Kits
Sources for GSTA2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources