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GSPT1 (G1 To S Phase Transition 1) is a Protein Coding gene. Among its related pathways are Viral mRNA Translation and Gene Expression. Gene Ontology (GO) annotations related to this gene include GTPase activity. An important paralog of this gene is GSPT2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0003723 | RNA binding | HDA | 22658674 |
GO:0003747 | translation release factor activity | IBA,IMP | 15326224 |
GO:0003924 | GTPase activity | IEA,TAS | 15326224 |
GO:0005515 | protein binding | IPI | 9620853 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005829 | cytosol | TAS | -- |
GO:0018444 | translation release factor complex | IBA | 21873635 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Viral mRNA Translation |
.77
|
|
2 | Translational Control | ||
3 | mRNA surveillance pathway | ||
4 | Gene Expression |
.48
|
|
5 | Metabolism of proteins |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000082 | G1/S transition of mitotic cell cycle | TAS | 2511002 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | 15326224 |
GO:0002184 | cytoplasmic translational termination | IBA | 21873635 |
GO:0006412 | translation | IBA | 21873635 |
GO:0006449 | regulation of translational termination | IMP | 30682371 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||||||||||
SP2: | - | - | |||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
Chimpanzee (Pan troglodytes) |
Mammalia | GSPT1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GSPT1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GSPT1 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
Mouse (Mus musculus) |
Mammalia | Gspt1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gspt1 30 |
|
||
Chicken (Gallus gallus) |
Aves | GSPT1 30 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gspt1 30 |
|
||
Str.3230 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.7810 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | gspt1l 31 |
|
ManyToMany | |
gspt1 30 30 31 |
|
ManyToMany | |||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009310 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | Elf 30 31 32 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | H19N07.1 32 |
|
|
|
erfa-3 31 |
|
OneToMany | |||
K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D17424g 30 |
|
||
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SUP35 30 31 |
|
OneToMany | |
A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AGL145W 30 |
|
||
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G18070 30 |
|
||
Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.1162 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os04g0270100 30 |
|
||
Os.16925 30 |
|
||||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9703 31 |
|
OneToMany | |
Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | sup35 30 |
|
||
Bread mold (Neurospora crassa) |
Ascomycetes | NCU04790 30 |
|
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1298n106 | CNV | deletion | 24896259 |
esv2343500 | CNV | deletion | 18987734 |
esv2651942 | CNV | deletion | 19546169 |
esv2713982 | CNV | deletion | 23290073 |
esv3553124 | CNV | deletion | 23714750 |
esv7500 | CNV | loss | 19470904 |
nsv1043909 | CNV | gain | 25217958 |
nsv1151765 | CNV | deletion | 26484159 |
nsv1735 | CNV | deletion | 18451855 |
nsv519892 | CNV | loss | 19592680 |
nsv524025 | CNV | loss | 19592680 |
nsv571458 | CNV | gain | 21841781 |
nsv958188 | CNV | deletion | 24416366 |
No disorders were found for GSPT1 Gene.