Aliases for GSPT1 Gene
Aliases for GSPT1 Gene
External Ids for GSPT1 Gene
- HGNC: 4621
- Entrez Gene: 2935
- Ensembl: ENSG00000103342
- OMIM: 139259
- UniProtKB: P15170
Previous GeneCards Identifiers for GSPT1 Gene
- GC16M011749
- GC16M012118
- GC16M011932
- GC16M011874
- GC16M011961
- GC16M011878
Summaries for GSPT1 Gene
GeneCards Summary for GSPT1 Gene
GSPT1 (G1 To S Phase Transition 1) is a Protein Coding gene. Among its related pathways are Translational Control and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include GTPase activity. An important paralog of this gene is GSPT2.
UniProtKB/Swiss-Prot for GSPT1 Gene
-
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GSPT1 Gene
Genomics for GSPT1 Gene
GeneHancer (GH) Regulatory Elements for GSPT1 Gene
Promoters and enhancers for GSPT1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around GSPT1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the GSPT1 gene promoter:
-
- p53
- IRF-1
- Arnt
- XBP-1
Regulatory Element Products
Genomic Locations for GSPT1 Gene
Genomic Locations for GSPT1 Gene
- chr16:11,868,128-11,916,662
- (GRCh38/hg38)
- Size:
- 48,535 bases
- Orientation:
- Minus strand
- chr16:11,961,985-12,010,519
- (GRCh37/hg19)
- Size:
- 48,535 bases
- Orientation:
- Minus strand
Genomic View for GSPT1 Gene
Genes around GSPT1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.13 by Entrez Gene
- 16p13.13 by HGNC
- 16p13.13 by Ensembl
GSPT1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GSPT1 Gene
Proteins for GSPT1 Gene
-
Protein details for GSPT1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P15170-ERF3A_HUMAN
- Recommended name:
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
- Protein Accession:
- P15170
- J3KQG6
- Q96GF2
Protein attributes for GSPT1 Gene
- Size:
- 499 amino acids
- Molecular mass:
- 55756 Da
- Quaternary structure:
-
- Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.
Three dimensional structures from OCA and Proteopedia for GSPT1 Gene
Protein Expression for GSPT1 Gene
Post-translational modifications for GSPT1 Gene
Other Protein References for GSPT1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GSPT1
- Novus Biologicals Antibodies for GSPT1
-
Abcam antibodies for GSPT1
- Invitrogen Antibodies for GSPT1 (AFLGC-GSPT1)
- GeneTex GSPT1 Antibody for GSPT1
-
Boster Bio Antibodies for GSPT1
-
Santa Cruz Biotechnology (SCBT) Antibodies for GSPT1
Protein Products
-
OriGene Purified Proteins for GSPT1
- Search Origene for MassSpec and Protein Over-expression Lysates for GSPT1
- Origene Custom Protein Services for GSPT1
- Novus Biologicals proteins for GSPT1
- antibodies-online: Search results for 4 available GSPT1 Proteins ranked by validation data
- Compare Top GSPT1 Proteins
-
Quality Products:
- Search GeneTex for Proteins for GSPT1
-
Abcam proteins for GSPT1
Assay Products
No data available for DME Specific Peptides for GSPT1 Gene
Domains & Families for GSPT1 Gene
Gene Families for GSPT1 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for GSPT1 Gene
Suggested Antigen Peptide Sequences for GSPT1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P15170UniProtKB/Swiss-Prot:
ERF3A_HUMAN :- Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily.
- Family:
-
- Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily.
Function for GSPT1 Gene
Molecular function for GSPT1 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
- GENATLAS Biochemistry:
- peptide chain factor release 3,interacting with and stimulating ERF1,controlled stop-codon directed release,mapping at the FRA16A locus
Phenotypes From GWAS Catalog for GSPT1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0003747 | translation release factor activity | IMP | 15326224 |
| GO:0003924 | GTPase activity | TAS,IEA | 15326224 |
| GO:0005515 | protein binding | IPI | 9620853 |
Phenotypes for GSPT1 Gene
- GenomeRNAi human phenotypes for GSPT1:
-
- G0/1 arrest
- Increased G1 DNA content
- Decreased NANOG protein expression
- Decreased OCT4 protein expression
- Decreased POU5F1-GFP protein expression
- Increased G1 length, increased G2 length
- Decreased viability
- no effect
- Decreased interferon-beta reporter expression
- Synthetic lethal with Ras
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased NF-kappaB reporter expression
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for GSPT1
-
CRISPR Products
-
OriGene CRISPR knockouts for GSPT1
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- genomics-online: gRNA clones - Search results for 112 available GSPT1 gene related products
- Overview of 112 available GSPT1 gene related products
- Applied Biological Materials CRISPR for GSPT1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSPT1
- GenScript: Design CRISPR guide RNA sequences for GSPT1
miRNA for GSPT1 Gene
- miRTarBase miRNAs that target GSPT1
-
- hsa-let-7b-5p (MIRT032238)
- hsa-mir-361-5p (MIRT044090)
- hsa-mir-183-5p (MIRT047129)
- hsa-mir-383-3p (MIRT282792)
- hsa-mir-873-5p (MIRT343125)
- hsa-mir-218-5p (MIRT440531)
- hsa-mir-1273e (MIRT444624)
- hsa-mir-7160-5p (MIRT444625)
- hsa-mir-1827 (MIRT444626)
- hsa-mir-4649-3p (MIRT444627)
- hsa-mir-940 (MIRT444628)
- hsa-mir-6893-5p (MIRT444629)
- hsa-mir-6808-5p (MIRT444630)
- hsa-mir-302f (MIRT444631)
- hsa-mir-6864-3p (MIRT476020)
- hsa-mir-3672 (MIRT476022)
- hsa-mir-6801-5p (MIRT476023)
- hsa-mir-769-5p (MIRT476024)
- hsa-mir-4786-5p (MIRT476025)
- hsa-mir-6500-3p (MIRT476026)
- hsa-mir-3614-5p (MIRT476027)
- hsa-mir-4275 (MIRT537013)
- hsa-mir-205-3p (MIRT537015)
- hsa-mir-576-3p (MIRT537016)
- hsa-mir-5197-5p (MIRT537017)
- hsa-mir-374c-3p (MIRT537018)
- hsa-mir-8055 (MIRT632864)
- hsa-mir-7977 (MIRT632865)
- hsa-mir-6884-5p (MIRT632866)
- hsa-mir-485-5p (MIRT632867)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSPT1
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- genomics-online: shRNA clones - Search results for 112 available GSPT1 gene related products
- Overview of 112 available GSPT1 gene related products
Clone Products
-
OriGene ORF clones in human for GSPT1
- RC225858
- RC225858L1
- RC225858L2
- RC225858L3
- RC225858L4
- RC226048
- RC226048L1
- RC226048L2
- RC226048L3
- RC226048L4
- RC229318
- RC229318L1
- RC229318L2
- RC229318L3
- RC229318L4
- RG225858
- RG226048
- RG229318
- RC225858L1V
- RC225858L2V
- RC225858L3V
- RC225858L4V
- RC226048L1V
- RC226048L2V
- RC226048L3V
- RC226048L4V
- RC229318L1V
- RC229318L2V
- RC229318L3V
- RC229318L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSPT1
- Applied Biological Materials Clones for GSPT1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GSPT1 Gene
Localization for GSPT1 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
- Cytosol (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | NAS | 15326224 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0018444 | translation release factor complex | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for GSPT1 Gene
Pathways & Interactions for GSPT1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Viral mRNA Translation |
.77
|
|
| 2 | mRNA surveillance pathway | ||
| 3 | Translational Control | ||
| 4 | Gene Expression |
.48
|
|
| 5 | Metabolism of proteins | ||
Pathways by source for GSPT1 Gene
7 Reactome pathways for GSPT1 Gene
1 KEGG pathway for GSPT1 Gene
1 Cell Signaling Technology pathway for GSPT1 Gene
Interacting Proteins for GSPT1 Gene
Selected Interacting proteins:
P15170-ERF3A_HUMAN
ENSP00000398131
for GSPT1 Gene via
MINT
STRING
UniProtKB
IID
GPS-Prot Interaction Network for GSPT1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | 2511002 |
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | 15326224 |
| GO:0002184 | cytoplasmic translational termination | IBA | -- |
| GO:0006412 | translation | IEA,IBA | -- |
| GO:0006415 | translational termination | TAS | -- |
No data available for SIGNOR curated interactions for GSPT1 Gene
Transcripts for GSPT1 Gene
mRNA/cDNA for GSPT1 Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (512) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000434724 7105 bps (uc002dbt.4)
- ENST00000439887 2509 bps (uc002dbu.4)
- ENST00000565267 1864 bps (uc059qxr.1)
- ENST00000563468 1962 bps (uc059qxs.1)
- ENST00000420576 1603 bps (uc010bux.4)
Unigene Clusters for GSPT1 Gene
- G1 to S phase transition 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for GSPT1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSPT1
- genomics-online: gRNA clones - Search results for 112 available GSPT1 gene related products
- Overview of 112 available GSPT1 gene related products
- Applied Biological Materials CRISPR for GSPT1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSPT1
- GenScript: Design CRISPR guide RNA sequences for GSPT1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSPT1
- Browse OriGene Inhibitory RNA Products For GSPT1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSPT1
- genomics-online: shRNA clones - Search results for 112 available GSPT1 gene related products
- Overview of 112 available GSPT1 gene related products
Clone Products
-
OriGene ORF clones in human for GSPT1
- RC225858
- RC225858L1
- RC225858L2
- RC225858L3
- RC225858L4
- RC226048
- RC226048L1
- RC226048L2
- RC226048L3
- RC226048L4
- RC229318
- RC229318L1
- RC229318L2
- RC229318L3
- RC229318L4
- RG225858
- RG226048
- RG229318
- RC225858L1V
- RC225858L2V
- RC225858L3V
- RC225858L4V
- RC226048L1V
- RC226048L2V
- RC226048L3V
- RC226048L4V
- RC229318L1V
- RC229318L2V
- RC229318L3V
- RC229318L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSPT1
- Applied Biological Materials Clones for GSPT1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||
| SP4: |
Expression for GSPT1 Gene
This gene is overexpressed in Lymph node (11.0), Peripheral blood mononuclear cells (7.4), and Amniocyte (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GSPT1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of GSPT1 Gene:
GSPT1SOURCE GeneReport for Unigene cluster for GSPT1 Gene:
Hs.528780Evidence on tissue expression from TISSUES for GSPT1 Gene
- Lung(4.6)
- Nervous system(3.8)
- Intestine(2.9)
Primer Products
-
OriGene qPCR primer pairs for GSPT1
-
OriGene qPCR primer pairs and template standards for GSPT1
- genomics-online: primer clones - Search results for 112 available GSPT1 gene related products
- Overview of 112 available GSPT1 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GSPT1 Gene
Orthologs for GSPT1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | GSPT1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | GSPT1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | GSPT1 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Gspt1 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC100911685 33 |
|
||
| chicken (Gallus gallus) |
Aves | GSPT1 34 33 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | gspt1 33 |
|
||
| Str.3230 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.7810 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | gspt1l 34 |
|
ManyToMany | |
| gspt1 34 33 33 |
|
ManyToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009310 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Elf 34 35 33 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | H19N07.1 35 |
|
|
|
| erfa-3 34 |
|
OneToMany | |||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D17424g 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SUP35 34 33 |
|
OneToMany | |
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGL145W 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G18070 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.1162 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0270100 33 |
|
||
| Os.16925 33 |
|
||||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.9703 34 |
|
OneToMany | |
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | sup35 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU04790 33 |
|
- Species where no ortholog for GSPT1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for GSPT1 Gene
- ENSEMBL:
- Gene Tree for GSPT1 (if available)
- TreeFam:
- Gene Tree for GSPT1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GSPT1: view image
Paralogs for GSPT1 Gene
(7) SIMAP similar genes for GSPT1 Gene using alignment to 4 proteins:
- ERF3A_HUMAN
- H3BMT9_HUMAN
- H3BR35_HUMAN
- H3BSV8_HUMAN
Pseudogenes.org Pseudogenes for GSPT1 Gene
Variants for GSPT1 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000010964 | -- | 11,907,545(-) | T/C | intron_variant | |
| rs1000027757 | -- | 11,887,816(-) | C/G | intron_variant | |
| rs1000094690 | -- | 11,886,304(-) | T/C | intron_variant | |
| rs1000114585 | -- | 11,881,891(-) | T/A | intron_variant | |
| rs1000166899 | -- | 11,881,699(-) | G/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1298n106 | CNV | deletion | 24896259 |
| esv2343500 | CNV | deletion | 18987734 |
| esv2651942 | CNV | deletion | 19546169 |
| esv2713982 | CNV | deletion | 23290073 |
| esv3553124 | CNV | deletion | 23714750 |
| esv7500 | CNV | loss | 19470904 |
| nsv1043909 | CNV | gain | 25217958 |
| nsv1151765 | CNV | deletion | 26484159 |
| nsv1735 | CNV | deletion | 18451855 |
| nsv519892 | CNV | loss | 19592680 |
| nsv524025 | CNV | loss | 19592680 |
| nsv571458 | CNV | gain | 21841781 |
| nsv958188 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.44;
90.96% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GSPT1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSPT1 Gene
Disorders for GSPT1 Gene
Additional Disease Information for GSPT1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for GSPT1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GSPT1 Gene
Publications for GSPT1 Gene
- A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells. (PMID: 2511002) Hoshino S … Ui M (The EMBO journal 1989) 2 3 4 58
- Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein. (PMID: 20418951) Kozlov G … Gehring K (PloS one 2010) 3 4 58
- SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. (PMID: 19417104) Yamashita A … Ohno S (Genes & development 2009) 3 4 58
- eRF3a/GSPT1 12-GGC allele increases the susceptibility for breast cancer development. (PMID: 19424636) Malta-Vacas J … Brito M (Oncology reports 2009) 3 22 58
- Differential expression of GSPT1 GGCn alleles in cancer. (PMID: 19963113) Malta-Vacas J … Brito M (Cancer genetics and cytogenetics 2009) 3 22 58
Products for GSPT1 Gene
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- Custom Antibody ServicesOriGene Antibodies for GSPT1
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- Browse OriGene Inhibitory RNA Products For GSPT1
- OriGene qPCR primer pairs for GSPT1
- OriGene qPCR primer pairs and template standards for GSPT1
- OriGene CRISPR knockouts for GSPT1
- OriGene ORF clones in human for GSPT1
- RC225858
- RC225858L1
- RC225858L2
- RC225858L3
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- RC226048
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- RC229318
- RC229318L1
- RC229318L2
- RC229318L3
- RC229318L4
- RG225858
- RG226048
- RG229318
- RC225858L1V
- RC225858L2V
- RC225858L3V
- RC225858L4V
- RC226048L1V
- RC226048L2V
- RC226048L3V
- RC226048L4V
- RC229318L1V
- RC229318L2V
- RC229318L3V
- RC229318L4V
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- genomics-online: cdna clones - Search results for 112 available GSPT1 gene related products
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Sources for GSPT1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
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- (119) Disease Ontology
- (120) Genetics Home Reference
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- (123) CDC
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- (125) NCBI Bookshelf
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- (128) ViGene Biosciences
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt