GSG1L2 Gene (Protein Coding)

GSG1 Like 2

GC17M009801
GIFtS:
17
See more...

Aliases for GSG1L2 Gene

Aliases for GSG1L2 Gene

  • GSG1 Like 2 2 3 5
  • Germ Cell-Specific Gene 1-Like Protein 2 3 4
  • GSG1-Like Protein 2 3 4
  • Putative Germ Cell-Specific Gene 1-Like Protein 2 3
  • Germ Cell-Specific Gene 1-Like Protein 2-Like 3
  • GSG1L2 5

External Ids for GSG1L2 Gene

Summaries for GSG1L2 Gene

GeneCards Summary for GSG1L2 Gene

GSG1L2 (GSG1 Like 2) is a Protein Coding gene. An important paralog of this gene is GSG1L.

Additional gene information for GSG1L2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GSG1L2 Gene

Genomics for GSG1L2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for GSG1L2 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH17J009819 Enhancer 0.3 dbSUPER 250.7 +1.3 1332 1.9 FOS GLP2R GSG1L2 HSALNG0114511 DHRS7C
GH17J009816 Enhancer 0.6 FANTOM5 0.7 +5.0 4961 0.3 RFX5 USF2 NFYC SP1 CREM CREB1 ZSCAN4 RFXANK ZNF157 HSALNG0114511 GAS7 GSG1L2 DHRS7C
GH17J009801 Enhancer 0.8 ENCODE dbSUPER 0.4 +19.7 19670 2.4 ZNF217 ELF1 MAX POLR2A RAD21 SIN3A SMC3 TBP TCF7L2 USF2 HSALNG0114509 ENSG00000283025 ENSG00000278944 DHRS7C GSG1L2 ENSG00000282882
GH17J009805 Enhancer 0.3 Ensembl 0.4 +16.2 16170 0.2 REST KLF16 ENSG00000283025 ENSG00000278944 DHRS7C GSG1L2
GH17J009797 Enhancer 0.3 dbSUPER 0.3 +23.5 23518 1.5 RAD21 CTCF RCVRN HSALNG0114509 DHRS7C piR-43106-090 ENSG00000278944 GSG1L2 ENSG00000282882
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GSG1L2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GSG1L2

Genomic Locations for GSG1L2 Gene

Latest Assembly
chr17:9,802,386-9,822,071
(GRCh38/hg38)
Size:
19,686 bases
Orientation:
Minus strand

Previous Assembly
chr17:9,705,703-9,725,388
(GRCh37/hg19 by Entrez Gene)
Size:
19,686 bases
Orientation:
Minus strand

chr17:9,694,544-9,725,388
(GRCh37/hg19 by Ensembl)
Size:
30,845 bases
Orientation:
Minus strand

Genomic View for GSG1L2 Gene

Genes around GSG1L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GSG1L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GSG1L2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for GSG1L2 Gene

Proteins for GSG1L2 Gene

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  3. Assay products for research

  • Protein details for GSG1L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MUP6-GS1L2_HUMAN
    Recommended name:
    Germ cell-specific gene 1-like protein 2
    Protein Accession:
    A8MUP6
    Secondary Accessions:
    • K7EL98

    Protein attributes for GSG1L2 Gene

    Size:
    293 amino acids
    Molecular mass:
    32443 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GSG1L2 Gene

Post-translational modifications for GSG1L2 Gene

  • Glycosylation at Asn59 and Asn67

Other Protein References for GSG1L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GSG1L2 Gene

Domains & Families for GSG1L2 Gene

Gene Families for GSG1L2 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for GSG1L2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8MUP6

UniProtKB/Swiss-Prot:

GS1L2_HUMAN :
  • Belongs to the GSG1 family.
Family:
  • Belongs to the GSG1 family.
genes like me logo Genes that share domains with GSG1L2: view

No data available for Suggested Antigen Peptide Sequences for GSG1L2 Gene

Function for GSG1L2 Gene

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  1. Animal Models for research
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  4. Inhibitory RNAs for research
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  6. Cell Lines for research

Phenotypes From GWAS Catalog for GSG1L2 Gene

Phenotypes for GSG1L2 Gene

GenomeRNAi human phenotypes for GSG1L2:
genes like me logo Genes that share phenotypes with GSG1L2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GSG1L2 Gene

Localization for GSG1L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GSG1L2 Gene

Membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GSG1L2 gene
Compartment Confidence
plasma membrane 4
extracellular 1

Gene Ontology (GO) - Cellular Components for GSG1L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GSG1L2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for GSG1L2 Gene

Pathways & Interactions for GSG1L2 Gene

PathCards logo

SuperPathways for GSG1L2 Gene

No Data Available

Interacting Proteins for GSG1L2 Gene

Gene Ontology (GO) - Biological Process for GSG1L2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GSG1L2 Gene

Drugs & Compounds for GSG1L2 Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for GSG1L2 Gene

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  2. miRNA products for research
  3. Inhibitory RNAs for research
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mRNA/cDNA for GSG1L2 Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for GSG1L2 Gene

No ASD Table

Relevant External Links for GSG1L2 Gene

GeneLoc Exon Structure for
GSG1L2

Expression for GSG1L2 Gene

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  2. Gene Expression Assays for research
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GSG1L2 Gene

Orthologs for GSG1L2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GSG1L2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia -- 31
  • 91 (a)
 OneToOne
Cow
(Bos Taurus)
 Mammalia LOC101904437 30
  • 80.84 (n)
-- 31
  • 73 (a)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Gm12302 30 31
  • 75.98 (n)
 OneToOne
Gsg1l2 17
Platypus
(Ornithorhynchus anatinus)
 Mammalia -- 31
  • 37 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves -- 31
  • 43 (a)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia -- 31
  • 45 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia LOC100495852 30
  • 62.83 (n)
Zebrafish
(Danio rerio)
 Actinopterygii si:ch211-138k19.2 31
  • 40 (a)
 OneToMany
gb:dt867253 31
  • 36 (a)
 OneToMany
CR812464.1 31
  • 33 (a)
 OneToMany
Species where no ortholog for GSG1L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for GSG1L2 Gene

ENSEMBL:
Gene Tree for GSG1L2 (if available)
TreeFam:
Gene Tree for GSG1L2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GSG1L2: view image

Paralogs for GSG1L2 Gene

Paralogs for GSG1L2 Gene

Pseudogenes.org Pseudogenes for GSG1L2 Gene

genes like me logo Genes that share paralogs with GSG1L2: view

Variants for GSG1L2 Gene

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dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for GSG1L2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for GSG1L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GSG1L2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for GSG1L2 Gene

Disorders for GSG1L2 Gene

Additional Disease Information for GSG1L2

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for GSG1L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GSG1L2 Gene

Publications for GSG1L2 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4
  2. A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. (PMID: 23509962) Greliche N … Trégouët DA (BMC medical genetics 2013) 3
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3

ExternalLinks

View latest publications for GSG1L2 gene in Mastermind

Products for GSG1L2 Gene

Sources for GSG1L2 Gene