Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-med... See more...
Aliases for GSDMB Gene
Aliases for GSDMB Gene
External Ids for GSDMB Gene
- HGNC: 23690
- Entrez Gene: 55876
- Ensembl: ENSG00000073605
- OMIM: 611221
- UniProtKB: Q8TAX9
Previous HGNC Symbols for GSDMB Gene
- GSDML
Previous GeneCards Identifiers for GSDMB Gene
- GC17M035315
- GC17M038060
- GC17M033854
Summaries for GSDMB Gene
-
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]
GeneCards Summary for GSDMB Gene
GSDMB (Gasdermin B) is a Protein Coding gene. Diseases associated with GSDMB include Oral Squamous Cell Carcinoma and Bronchial Disease. An important paralog of this gene is GSDMA.
UniProtKB/Swiss-Prot Summary for GSDMB Gene
-
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).
Additional gene information for GSDMB Gene
- HGNC(23690)
- Entrez Gene(55876)
- Ensembl(ENSG00000073605)
- OMIM(611221)
- UniProtKB(Q8TAX9)
- Open Targets Platform(ENSG00000073605)
- Monarch Initiative
- Search for GSDMB at DataMed
- Search for GSDMB at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GSDMB Gene
Genomics for GSDMB Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GSDMB Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GSDMB on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GSDMB
- Top Transcription factor binding sites by QIAGEN in the GSDMB gene promoter:
-
- AP-4
- C/EBPbeta
- COUP
- COUP-TF
- COUP-TF1
- HNF-4alpha2
Genomic Locations for GSDMB Gene
Genomic Locations for GSDMB Gene
- chr17:39,904,595-39,919,854
- (GRCh38/hg38)
- Size:
- 15,260 bases
- Orientation:
- Minus strand
- chr17:38,060,848-38,076,107
- (GRCh37/hg19)
- Size:
- 15,260 bases
- Orientation:
- Minus strand
Genomic View for GSDMB Gene
Genes around GSDMB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.1 by HGNC
- 17q21.1 by Entrez Gene
- 17q21.1 by Ensembl
GSDMB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GSDMB Gene
Proteins for GSDMB Gene
-
Protein details for GSDMB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TAX9-GSDMB_HUMAN
- Recommended name:
- Gasdermin-B
- Protein Accession:
- Q8TAX9
- B4DKK7
- Q7Z377
- Q8WY76
- Q9NX71
- Q9P163
Protein attributes for GSDMB Gene
- Size:
- 411 amino acids
- Molecular mass:
- 46786 Da
- Quaternary structure:
-
- The N-terminal moiety forms homooligomer; disulfide-linked. May form an 16-mer complex. Oligomerization occurs in the presence of membranes.
- Miscellaneous:
-
- The GSDML gene is predicted to be generated due to a duplication of GSDM gene; the rodent GSDML ortholog failed to be yet identified. The evolutionary recombination hotspot around GSDML-GSDM locus is closely related to the oncogenomic recombination hotspot or fragile sites within the human genome.
- Long terminal repeat (LTR) of endogenous retroviruse HERV-H with reverse orientation may serve as alternative promoters of GSDML gene.
- GSDML may be used as predictive markers of cervical lymph node metastasis and may help, with a panel of other genes, to discriminate between primary tumors of oral squamous cell carcinoma that metastasize to cervical lymph node and those that do not metastasize.
Protein Expression for GSDMB Gene
Post-translational modifications for GSDMB Gene
Other Protein References for GSDMB Gene
Antibody Products
- LifeSpan BioSciences GSDMB / Gasdermin-Like Antibody
-
Custom Antibody ServicesOriGene Antibodies for GSDMB
- Novus Biologicals Antibodies for GSDMB
-
Abcam antibodies for GSDMB
- Invitrogen Antibodies for GSDMB (AFLGC-GSDMB)
-
Biorbyt antibodies for GSDMB
-
Boster Bio Antibodies for GSDMB
-
Santa Cruz Biotechnology (SCBT) Antibodies for GSDMB
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for GSDMB
- Origene Custom Protein Services for GSDMB
- Novus Biologicals proteins for GSDMB
- antibodies-online: Show 3 available Gasdermin B Proteins ranked by validation data
- Compare Top Gasdermin B Proteins
-
Quality Products:
-
Abcam proteins for GSDMB
No data available for DME Specific Peptides for GSDMB Gene
Domains & Families for GSDMB Gene
Gene Families for GSDMB Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transporters
Protein Domains for GSDMB Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for GSDMB Gene
- GenScript: Design optimal peptide antigens:
-
- Gasdermin-like isoform GSDML1 (B2CM70_HUMAN)
- cDNA FLJ59250, weakly similar to Gasdermin (B4DKK7_HUMAN)
- Gasdermin-like protein (GSDMB_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8TAX9UniProtKB/Swiss-Prot:
GSDMB_HUMAN :- Intramolecular interactions between N- and C-terminal domains may be important for autoinhibition in the absence of activation signal. The intrinsic pyroptosis-inducing activity is carried by the N-terminal domain.
- Belongs to the gasdermin family.
- Domain:
-
- Intramolecular interactions between N- and C-terminal domains may be important for autoinhibition in the absence of activation signal. The intrinsic pyroptosis-inducing activity is carried by the N-terminal domain.
- Family:
-
- Belongs to the gasdermin family.
Function for GSDMB Gene
Molecular function for GSDMB Gene
- UniProtKB/Swiss-Prot Function:
- The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).
Phenotypes From GWAS Catalog for GSDMB Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001786 | phosphatidylserine binding | IBA | 21873635 |
| GO:0003674 | molecular_function | ND | -- |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | IBA | 21873635 |
| GO:0070273 | phosphatidylinositol-4-phosphate binding | IBA | 21873635 |
Phenotypes for GSDMB Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GSDMB - Select products 50% OFF >
- * GSDMB CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for GSDMB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSDMB
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSDMB
miRNA for GSDMB Gene
- miRTarBase miRNAs that target GSDMB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSDMB
- Browse OriGene Inhibitory RNA Products For GSDMB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSDMB
Clone Products
- Applied Biological Materials (abm): Clones for GSDMB - Select products 50% OFF >
- * GSDMB as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for GSDMB
- RC219044
- RC219044L1
- RC219044L2
- RC219044L3
- RC219044L4
- RC224054
- RC224054L3
- RC224054L4
- RC228325
- RC228325L3
- RC228325L4
- RC228330
- RC228330L1
- RC228330L2
- RC228330L3
- RC228330L4
- RG219044
- RG224054
- RG228325
- RG228330
- RC219044L1V
- RC219044L2V
- RC219044L3V
- RC219044L4V
- RC224054L3V
- RC224054L4V
- RC228325L3V
- RC228325L4V
- RC228330L1V
- RC228330L2V
- RC228330L3V
- RC228330L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for GSDMB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSDMB
Cell Line Products
-
Horizon Cell Lines for GSDMB
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GSDMB Gene
Localization for GSDMB Gene
Subcellular locations from UniProtKB/Swiss-Prot for GSDMB Gene
- Cytoplasm. Cytoplasm, cytosol. Cell membrane. Note=Vesicular localization in the apical region of gastric chief cells and colonic surface mucous cells, and the basal region of neuroendocrine cells. {ECO:0000269 PubMed:18038310}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| cytosol | 4 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for GSDMB Gene
Interacting Proteins for GSDMB Gene
GPS-Prot Interaction Network for GSDMB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
| GO:0012501 | programmed cell death | IEA | -- |
| GO:0042742 | defense response to bacterium | IBA | 21873635 |
| GO:0070269 | pyroptosis | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for GSDMB Gene
Transcripts for GSDMB Gene
mRNA/cDNA for GSDMB Gene
- 5 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000309481 1500 nts (view in UCSC)
- ENST00000360317 1468 nts (view in UCSC)
- ENST00000394175 1626 nts (view in UCSC)
- ENST00000394179 1427 nts (view in UCSC)
- ENST00000418519 1597 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GSDMB - Select products 50% OFF >
- * GSDMB CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for GSDMB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSDMB
-
Santa Cruz Biotechnology (SCBT) CRISPR for GSDMB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSDMB
- Browse OriGene Inhibitory RNA Products For GSDMB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSDMB
Clone Products
- Applied Biological Materials (abm): Clones for GSDMB - Select products 50% OFF >
- * GSDMB as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for GSDMB
- RC219044
- RC219044L1
- RC219044L2
- RC219044L3
- RC219044L4
- RC224054
- RC224054L3
- RC224054L4
- RC228325
- RC228325L3
- RC228325L4
- RC228330
- RC228330L1
- RC228330L2
- RC228330L3
- RC228330L4
- RG219044
- RG224054
- RG228325
- RG228330
- RC219044L1V
- RC219044L2V
- RC219044L3V
- RC219044L4V
- RC224054L3V
- RC224054L4V
- RC228325L3V
- RC228325L4V
- RC228330L1V
- RC228330L2V
- RC228330L3V
- RC228330L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for GSDMB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSDMB
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - |
Relevant External Links for GSDMB Gene
- GeneLoc Exon Structure for
- GSDMB
Expression for GSDMB Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
-
Epidermis (Integumentary System)
- Basal Keratinocytes Embryonic Epidermis
-
Epithelial Cells
- Basal Keratinocytes Embryonic Epidermis
-
Hair
- Basal Keratinocytes Embryonic Epidermis
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for GSDMB Gene
This gene is overexpressed in Liver (x4.8), Colon - Transverse (x4.2), and Small Intestine - Terminal Ileum (x4.1).
This gene is overexpressed in Stomach (26.8), Islet of Langerhans (15.1), and Rectum (15.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GSDMB Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GSDMB
SOURCE GeneReport for Unigene cluster for GSDMB Gene:
Hs.306777mRNA Expression by UniProt/SwissProt for GSDMB Gene:
Q8TAX9-GSDMB_HUMAN
Tissue specificity:
In the gastrointestinal tract, expressed in proliferating cells, including in the basal cell layer of esophagus and in isthmus/neck of stomach.
Evidence on tissue expression from TISSUES for GSDMB Gene
- Intestine(4.5)
- Lung(4.5)
- Blood(2.4)
- Stomach(2.3)
- Skin(2.3)
- Liver(2.1)
- Lymph node(2.1)
Primer Products
-
OriGene qPCR primer pairs for GSDMB
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GSDMB Gene
Orthologs for GSDMB Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GSDMB 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GSDMB 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GSDMB 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | GSDMB 31 |
|
OneToOne |
- Species where no ortholog for GSDMB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for GSDMB Gene
- ENSEMBL:
- Gene Tree for GSDMB (if available)
- TreeFam:
- Gene Tree for GSDMB (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GSDMB: view image
Paralogs for GSDMB Gene
Variants for GSDMB Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GSDMB Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 728833 | Benign: not provided | 39,917,245(-) | G/A | SYNONYMOUS_VARIANT | |
| 761523 | Likely Benign: not provided | 39,905,958(-) | G/A | SYNONYMOUS_VARIANT | |
| VAR_042634 | A breast cancer sample | p.Asp245Gly | |||
| rs12450091 | - | p.Glu122Gly | |||
| rs16965388 | - | p.Arg325Cys |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3573064 | CNV | gain | 25503493 |
| esv3640549 | CNV | loss | 21293372 |
| nsv1146669 | OTHER | inversion | 26484159 |
Residual Variation Intolerance Score:
75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.87;
93.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GSDMB Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSDMB Gene
Disorders for GSDMB Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| oral squamous cell carcinoma |
|
|
| bronchial disease |
|
|
| asthma |
|
|
Search GSDMB in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GSDMB
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GSDMB Gene
Publications for GSDMB Gene
- Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. (PMID: 19133921) Wu H … London SJ (Allergy 2009) 3 23 41
- Differential expression and localisation of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic, and colon tissues. (PMID: 18038310) Carl-McGrath S … Röcken C (Pathology 2008) 3 4 23
- Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner. (PMID: 17350798) Tamura M … Shiroishi T (Genomics 2007) 2 3 4
- Transcriptional control of the HERV-H LTR element of the GSDML gene in human tissues and cancer cells. (PMID: 16625320) Sin HS … Kim HS (Archives of virology 2006) 3 4 23
- Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon. (PMID: 15010812) Katoh M … Katoh M (International journal of oncology 2004) 2 3 23
ExternalLinks
Products for GSDMB Gene
- Custom Antibody ServicesOriGene Antibodies for GSDMB
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for GSDMB
- Origene Custom Protein Services for GSDMB
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GSDMB
- Browse OriGene Inhibitory RNA Products For GSDMB
- OriGene qPCR primer pairs for GSDMB
- OriGene CRISPR knockouts for GSDMB
- OriGene ORF clones in human for GSDMB
- RC219044
- RC219044L1
- RC219044L2
- RC219044L3
- RC219044L4
- RC224054
- RC224054L3
- RC224054L4
- RC228325
- RC228325L3
- RC228325L4
- RC228330
- RC228330L1
- RC228330L2
- RC228330L3
- RC228330L4
- RG219044
- RG224054
- RG228325
- RG228330
- RC219044L1V
- RC219044L2V
- RC219044L3V
- RC219044L4V
- RC224054L3V
- RC224054L4V
- RC228325L3V
- RC228325L4V
- RC228330L1V
- RC228330L2V
- RC228330L3V
- RC228330L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For GSDMB
- Sino Biological Human cDNA Clone for GSDMB
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for GSDMB
- Novus Biologicals proteins for GSDMB
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for GSDMB
- Abcam proteins for GSDMB
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for GSDMB (AFLGC-GSDMB)
- VectorBuilder Custom and pre-made DNA vectors for GSDMB (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GSDMB (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GSDMB (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GSDMB CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GSDMB
- antibodies-online: Show 15 available Gasdermin B Antibodies ranked by validation data
- Compare Top Gasdermin B Antibodies
- antibodies-online: Search results for available Gasdermin B related products ranked by validation data
- antibodies-online: Show 3 available Gasdermin B Proteins ranked by validation data
- Compare Top Gasdermin B Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for GSDMB
- Search Santa Cruz Biotechnology (SCBT) for GSDMB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GSDMB
- Horizon Cell Lines for GSDMB
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GSDMB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GSDMB
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GSDMB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GSDMB
- Boster Bio Antibodies for GSDMB
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for GSDMB
Sources for GSDMB Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB