Aliases for GRXCR2 Gene
External Ids for GRXCR2 Gene
Previous GeneCards Identifiers for GRXCR2 Gene
This gene encodes a protein containing a glutaredoxin domain, which functions in protein S-glutathionylation. A mutation in this gene was found in a family with autoosomal recessive nonsyndromic sensorineural deafness-101. [provided by RefSeq, Jun 2014]
GeneCards Summary for GRXCR2 Gene
GRXCR2 (Glutaredoxin And Cysteine Rich Domain Containing 2) is a Protein Coding gene. Diseases associated with GRXCR2 include Deafness, Autosomal Recessive 101 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Gene Ontology (GO) annotations related to this gene include unfolded protein binding and heat shock protein binding. An important paralog of this gene is GRXCR1.
UniProtKB/Swiss-Prot Summary for GRXCR2 Gene
Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection.