Aliases for GRXCR1 Gene
External Ids for GRXCR1 Gene
Previous HGNC Symbols for GRXCR1 Gene
Previous GeneCards Identifiers for GRXCR1 Gene
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010]
GeneCards Summary for GRXCR1 Gene
GRXCR1 (Glutaredoxin And Cysteine Rich Domain Containing 1) is a Protein Coding gene. Diseases associated with GRXCR1 include Deafness, Autosomal Recessive 25 and Branchiootic Syndrome 1. Gene Ontology (GO) annotations related to this gene include unfolded protein binding and heat shock protein binding. An important paralog of this gene is GRXCR2.
UniProtKB/Swiss-Prot Summary for GRXCR1 Gene
May play a role in actin filament architecture in developing stereocilia of sensory cells.