Aliases for GRWD1 Gene
External Ids for GRWD1 Gene
Previous GeneCards Identifiers for GRWD1 Gene
This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012]
GeneCards Summary for GRWD1 Gene
GRWD1 (Glutamate Rich WD Repeat Containing 1) is a Protein Coding gene. An important paralog of this gene is WDR59.
UniProtKB/Swiss-Prot for GRWD1 Gene
Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness (PubMed:25990725).