Aliases for GRPEL1 Gene
External Ids for GRPEL1 Gene
Previous GeneCards Identifiers for GRPEL1 Gene
GeneCards Summary for GRPEL1 Gene
GRPEL1 (GrpE Like 1, Mitochondrial) is a Protein Coding gene. Diseases associated with GRPEL1 include Lymphangitis and Human Monocytic Ehrlichiosis. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL2.
UniProtKB/Swiss-Prot Summary for GRPEL1 Gene
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562).