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Aliases for GRM7 Gene

Aliases for GRM7 Gene

  • Glutamate Metabotropic Receptor 7 2 3 5
  • Protein Phosphatase 1, Regulatory Subunit 87 2 3
  • Glutamate Receptor, Metabotropic 7 2 3
  • GPRC1G 3 4
  • MGLUR7 3 4
  • Metabotropic Glutamate Receptor 7 3
  • PPP1R87 3
  • MGluR7 4
  • GLUR7 3
  • MGLU7 3

External Ids for GRM7 Gene

Previous GeneCards Identifiers for GRM7 Gene

  • GC03P006816
  • GC03P006877

Summaries for GRM7 Gene

Entrez Gene Summary for GRM7 Gene

  • L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

GeneCards Summary for GRM7 Gene

GRM7 (Glutamate Metabotropic Receptor 7) is a Protein Coding gene. Diseases associated with GRM7 include Age-Related Hearing Loss and Lubs X-Linked Mental Retardation Syndrome. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and PDZ domain binding. An important paralog of this gene is GRM8.

UniProtKB/Swiss-Prot for GRM7 Gene

  • G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Tocris Summary for GRM7 Gene

  • Metabotropic Glutamate (mGlu) group III receptors are members of the metabotropic class of glutamate receptors, which also includes mGlu group I and mGlu group II receptors. Group III receptors are divided into four subtypes, mGlu4, mGlu6, mGlu7 and mGlu8.

Gene Wiki entry for GRM7 Gene

Additional gene information for GRM7 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GRM7 Gene

Genomics for GRM7 Gene

GeneHancer (GH) Regulatory Elements for GRM7 Gene

Promoters and enhancers for GRM7 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J006769 Promoter 1 EPDnew 650.7 -0.3 -348 0.1 HDAC1 ATF1 CTBP1 MTA3 POLR2A FOXK2 NCOR1 TRIM24 ATF7 L3MBTL2 GRM7 GRM7-AS3 ENSG00000223719 GC03M006543
GH03J006860 Promoter/Enhancer 1 EPDnew Ensembl 650.2 +91.4 91388 2.6 MXI1 POLR2A SUZ12 SCRT2 CHD2 EZH2 GRM7 GRM7-AS2 LOC105376945 GC03M006543
GH03J007305 Enhancer 0.8 Ensembl ENCODE 6.2 +538.2 538166 5.1 RXRA JUN NR2F2 SP1 POLR2A RCOR1 MAFK CHD2 GRM7 GC03M007443 GC03M006543
GH03J007205 Enhancer 0.8 Ensembl ENCODE 4.6 +436.0 435955 0.6 NR2F1 BMI1 MEF2B DPF2 YY1 SP1 IKZF1 ZBTB33 ATF7 GRM7 GC03M006543 GC03M007443
GH03J007271 Enhancer 0.2 ENCODE 4.5 +501.7 501730 0.3 GRM7 GC03M007443 GC03M006543
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GRM7 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GRM7 gene promoter:
  • LCR-F1
  • Egr-1
  • Pax-6
  • c-Myb
  • S8
  • AREB6
  • AP-4
  • FOXL1
  • POU2F1a

Genomic Locations for GRM7 Gene

Genomic Locations for GRM7 Gene
chr3:6,770,001-7,741,533
(GRCh38/hg38)
Size:
971,533 bases
Orientation:
Plus strand
chr3:6,811,688-7,783,218
(GRCh37/hg19)
Size:
971,531 bases
Orientation:
Plus strand

Genomic View for GRM7 Gene

Genes around GRM7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GRM7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GRM7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GRM7 Gene

Proteins for GRM7 Gene

  • Protein details for GRM7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14831-GRM7_HUMAN
    Recommended name:
    Metabotropic glutamate receptor 7
    Protein Accession:
    Q14831
    Secondary Accessions:
    • Q8NFS2
    • Q8NFS3
    • Q8NFS4

    Protein attributes for GRM7 Gene

    Size:
    915 amino acids
    Molecular mass:
    102251 Da
    Quaternary structure:
    • Interacts with PICK1.

    Three dimensional structures from OCA and Proteopedia for GRM7 Gene

    Alternative splice isoforms for GRM7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GRM7 Gene

Post-translational modifications for GRM7 Gene

  • Glycosylation at Asn572, Asn486, isoforms=2, 3, 4, 5458, and isoforms=2, 3, 4, 598
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GRM7 Gene

Domains & Families for GRM7 Gene

Gene Families for GRM7 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted intracellular proteins
  • Predicted membrane proteins

Suggested Antigen Peptide Sequences for GRM7 Gene

Graphical View of Domain Structure for InterPro Entry

Q14831

UniProtKB/Swiss-Prot:

GRM7_HUMAN :
  • Belongs to the G-protein coupled receptor 3 family.
Family:
  • Belongs to the G-protein coupled receptor 3 family.
genes like me logo Genes that share domains with GRM7: view

Function for GRM7 Gene

Molecular function for GRM7 Gene

UniProtKB/Swiss-Prot Function:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Phenotypes From GWAS Catalog for GRM7 Gene

Gene Ontology (GO) - Molecular Function for GRM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001642 group III metabotropic glutamate receptor activity IDA 9144652
GO:0004871 obsolete signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0005246 calcium channel regulator activity IBA --
GO:0008066 glutamate receptor activity IDA 9473604
genes like me logo Genes that share ontologies with GRM7: view
genes like me logo Genes that share phenotypes with GRM7: view

Animal Models for GRM7 Gene

MGI Knock Outs for GRM7:

Animal Model Products

miRNA for GRM7 Gene

miRTarBase miRNAs that target GRM7

Clone Products

  • Addgene plasmids for GRM7

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GRM7 Gene

Localization for GRM7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GRM7 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GRM7 gene
Compartment Confidence
plasma membrane 5
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for GRM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS,IEA --
GO:0005887 integral component of plasma membrane IBA,NAS 9473604
GO:0005938 cell cortex IDA 9630572
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IDA,IEA 12746871
genes like me logo Genes that share ontologies with GRM7: view

Pathways & Interactions for GRM7 Gene

genes like me logo Genes that share pathways with GRM7: view

Gene Ontology (GO) - Biological Process for GRM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001662 NOT behavioral fear response IMP 17167337
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS,IEA --
GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway IDA 9473604
GO:0007216 G-protein coupled glutamate receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with GRM7: view

No data available for SIGNOR curated interactions for GRM7 Gene

Drugs & Compounds for GRM7 Gene

(125) Drugs for GRM7 Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Glutamic Acid Approved Nutra Full agonist, Agonist, antagonist, Target 251
Risperidone Approved, Investigational Pharma Antagonist, Inverse agonist SR-2A inhibitor 498
Spaglumic acid Approved Pharma Selective mGlu3 agonist 0
Fenobam Investigational Pharma Negative, Allosteric regulator 0
Kynurenic acid Investigational Pharma Agonist 4

(3) Additional Compounds for GRM7 Gene - From: IUPHAR and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
L-SOP
Full agonist, Agonist

(5) Tocris Compounds for GRM7 Gene

Compound Action Cas Number
(RS)-PPG Potent, selective mGlu8 agonist 120667-15-4
(S)-3,4-DCPG Potent, selective mGlu8a agonist 201730-11-2
ACPT-I Group III mGlu agonist 194918-76-8
L-AP4 Selective group III mGlu agonist 23052-81-5
O-Phospho-L-serine Group III mGlu agonist 407-41-0
genes like me logo Genes that share compounds with GRM7: view

Transcripts for GRM7 Gene

mRNA/cDNA for GRM7 Gene

(11) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GRM7 Gene

Glutamate receptor, metabotropic 7:
Representative Sequences:

Clone Products

  • Addgene plasmids for GRM7

Alternative Splicing Database (ASD) splice patterns (SP) for GRM7 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1: - - - - -
SP2: - - - - - -
SP3:

Relevant External Links for GRM7 Gene

GeneLoc Exon Structure for
GRM7
ECgene alternative splicing isoforms for
GRM7

Expression for GRM7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GRM7 Gene

mRNA differential expression in normal tissues according to GTEx for GRM7 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x6.9), Brain - Hypothalamus (x6.0), Brain - Anterior cingulate cortex (BA24) (x5.8), Brain - Hippocampus (x5.1), Brain - Cortex (x4.9), and Brain - Nucleus accumbens (basal ganglia) (x4.3).

Protein differential expression in normal tissues from HIPED for GRM7 Gene

This gene is overexpressed in Placenta (23.8), Heart (22.5), and Platelet (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GRM7 Gene



Protein tissue co-expression partners for GRM7 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GRM7 Gene:

GRM7

SOURCE GeneReport for Unigene cluster for GRM7 Gene:

Hs.660131

mRNA Expression by UniProt/SwissProt for GRM7 Gene:

Q14831-GRM7_HUMAN
Tissue specificity: Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.

Evidence on tissue expression from TISSUES for GRM7 Gene

  • Nervous system(4.8)
genes like me logo Genes that share expression patterns with GRM7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for GRM7 Gene

Orthologs for GRM7 Gene

This gene was present in the common ancestor of animals.

Orthologs for GRM7 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia GRM7 34
  • 100 (a)
OneToOne
LOC484674 33
  • 94.72 (n)
chimpanzee
(Pan troglodytes)
Mammalia GRM7 34 33
  • 99.45 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GRM7 34
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GRM7 34 33
  • 92.82 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Grm7 16 34 33
  • 91.66 (n)
rat
(Rattus norvegicus)
Mammalia Grm7 33
  • 91.51 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 71 (a)
ManyToMany
chicken
(Gallus gallus)
Aves GRM7 34 33
  • 83.26 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GRM7 34
  • 89 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia grm7 33
  • 76.63 (n)
Str.3166 33
zebrafish
(Danio rerio)
Actinopterygii LOC100331190 33
  • 73.48 (n)
fruit fly
(Drosophila melanogaster)
Insecta Glu-RA 35
  • 47 (a)
CG30361 35
  • 41 (a)
worm
(Caenorhabditis elegans)
Secernentea mgl-3 33
  • 47.48 (n)
mgl-1 35
  • 38 (a)
Species where no ortholog for GRM7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GRM7 Gene

ENSEMBL:
Gene Tree for GRM7 (if available)
TreeFam:
Gene Tree for GRM7 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GRM7: view image

Paralogs for GRM7 Gene

Paralogs for GRM7 Gene

(9) SIMAP similar genes for GRM7 Gene using alignment to 9 proteins:

  • GRM7_HUMAN
  • B7ZKK0_HUMAN
  • B9EGG9_HUMAN
  • C9JMT3_HUMAN
  • C9JU97_HUMAN
  • F8WAW6_HUMAN
  • F8WCR9_HUMAN
  • H7C3K2_HUMAN
  • L8E797_HUMAN
genes like me logo Genes that share paralogs with GRM7: view

Variants for GRM7 Gene

Sequence variations from dbSNP and Humsavar for GRM7 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000000224 -- 6,914,691(+) G/A intron_variant
rs1000000582 -- 7,059,995(+) A/G intron_variant
rs1000002527 -- 7,515,961(+) A/G intron_variant
rs1000002917 -- 6,892,818(+) AGGCTA/A intron_variant
rs1000004219 -- 7,635,841(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GRM7 Gene

Variant ID Type Subtype PubMed ID
dgv4674n100 CNV gain 25217958
dgv4675n100 CNV gain 25217958
dgv8204n54 CNV loss 21841781
dgv8205n54 CNV loss 21841781
dgv8206n54 CNV loss 21841781
esv1005105 CNV insertion 20482838
esv1450820 CNV insertion 17803354
esv22695 CNV loss 19812545
esv2342652 CNV deletion 18987734
esv24058 CNV loss 19812545
esv2455660 CNV deletion 19546169
esv2590123 CNV insertion 19546169
esv2656815 CNV deletion 23128226
esv2660996 CNV deletion 23128226
esv2662447 CNV deletion 23128226
esv2664422 CNV deletion 23128226
esv2670179 CNV deletion 23128226
esv2674760 CNV deletion 23128226
esv2678085 CNV deletion 23128226
esv2724857 CNV deletion 23290073
esv2724858 CNV deletion 23290073
esv2724859 CNV deletion 23290073
esv2724860 CNV deletion 23290073
esv2724862 CNV deletion 23290073
esv2752015 CNV loss 17911159
esv2759128 CNV gain 17122850
esv2763214 CNV gain 21179565
esv28710 CNV gain 19812545
esv3304662 CNV mobile element insertion 20981092
esv3333219 CNV insertion 20981092
esv3561412 CNV deletion 23714750
esv3561418 CNV deletion 23714750
esv3561420 CNV deletion 23714750
esv3568597 CNV loss 25503493
esv3568599 CNV loss 25503493
esv3568600 CNV loss 25503493
esv3568601 CNV loss 25503493
esv3575541 CNV gain 25503493
esv3595176 CNV loss 21293372
esv3595177 CNV loss 21293372
esv3595181 CNV loss 21293372
esv3595182 CNV loss 21293372
esv3595183 CNV loss 21293372
esv3595185 CNV loss 21293372
esv3595187 CNV gain 21293372
esv3595189 CNV loss 21293372
esv3595190 CNV loss 21293372
esv3595191 CNV loss 21293372
esv3595196 CNV gain 21293372
esv3595197 CNV gain 21293372
esv3595198 CNV loss 21293372
esv3595199 CNV gain 21293372
esv3893653 CNV loss 25118596
esv3893654 CNV loss 25118596
esv3893655 CNV loss 25118596
esv3893658 CNV loss 25118596
esv5346 CNV loss 18987735
esv8633 CNV loss 19470904
esv9380 OTHER inversion 19470904
esv998955 CNV deletion 20482838
nsv1002130 CNV loss 25217958
nsv1006252 CNV gain 25217958
nsv1006339 CNV loss 25217958
nsv1006895 CNV gain 25217958
nsv1007359 CNV loss 25217958
nsv1013659 CNV loss 25217958
nsv1072236 CNV deletion 25765185
nsv1072662 CNV deletion 25765185
nsv1072663 CNV deletion 25765185
nsv1072664 CNV deletion 25765185
nsv1072816 CNV deletion 25765185
nsv1074566 CNV deletion 25765185
nsv1123619 CNV deletion 24896259
nsv1123620 CNV deletion 24896259
nsv1123621 CNV deletion 24896259
nsv1131677 CNV deletion 24896259
nsv1131678 CNV deletion 24896259
nsv236588 CNV deletion 16902084
nsv237180 CNV deletion 16902084
nsv237477 CNV deletion 16902084
nsv460377 CNV gain 19166990
nsv507081 OTHER sequence alteration 20534489
nsv518755 CNV loss 19592680
nsv524074 CNV loss 19592680
nsv524307 CNV loss 19592680
nsv526975 CNV loss 19592680
nsv589568 CNV gain 21841781
nsv589569 CNV gain 21841781
nsv589570 CNV loss 21841781
nsv589573 CNV gain 21841781
nsv589574 CNV loss 21841781
nsv589575 CNV loss 21841781
nsv589582 CNV loss 21841781
nsv589583 CNV loss 21841781
nsv589584 CNV gain 21841781
nsv589585 CNV loss 21841781
nsv818125 CNV loss 17921354
nsv818126 CNV loss 17921354
nsv834610 CNV gain 17160897
nsv956823 CNV deletion 24416366
nsv997695 CNV loss 25217958

Variation tolerance for GRM7 Gene

Residual Variation Intolerance Score: 7.92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.70; 78.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GRM7 Gene

Human Gene Mutation Database (HGMD)
GRM7
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GRM7

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GRM7 Gene

Disorders for GRM7 Gene

MalaCards: The human disease database

(4) MalaCards diseases for GRM7 Gene - From: HGMD, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search GRM7 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GRM7

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with GRM7: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GRM7 Gene

Publications for GRM7 Gene

  1. Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS. (PMID: 8840028) Makoff A … Emson P (Brain research. Molecular brain research 1996) 2 3 4 22 58
  2. Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia. (PMID: 19351574) Shibata H … Fukumaki Y (Psychiatry research 2009) 3 22 44 58
  3. GRM7 variants confer susceptibility to age-related hearing impairment. (PMID: 19047183) Friedman RA … Van Camp G (Human molecular genetics 2009) 3 22 44 58
  4. A family-based association study of DNA sequence variants in GRM7 with schizophrenia in an Indonesian population. (PMID: 19638256) Ganda C … Wildenauer DB (The international journal of neuropsychopharmacology 2009) 3 22 44 58
  5. A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia. (PMID: 18329248) Ohtsuki T … Arinami T (Schizophrenia research 2008) 3 22 44 58

Products for GRM7 Gene

  • Addgene plasmids for GRM7

Sources for GRM7 Gene

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