Free for academic non-profit institutions. Other users need a Commercial license
Aliases for GRINA Gene
Aliases for GRINA Gene
- Glutamate Ionotropic Receptor NMDA Type Subunit Associated Protein 1 2 3 5
- TMBIM3 2 3 4
- LFG1 2 3 4
- Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Associated Protein 1 (Glutamate Binding) 2 3
- Transmembrane BAX Inhibitor Motif-Containing Protein 3 3 4
- Transmembrane BAX Inhibitor Motif Containing 3 2 3
- Glutamate [NMDA] Receptor-Associated Protein 1 3 4
External Ids for GRINA Gene
- HGNC: 4589
- Entrez Gene: 2907
- Ensembl: ENSG00000178719
- OMIM: 138251
- UniProtKB: Q7Z429
Previous HGNC Symbols for GRINA Gene
- NMDARA1
Previous GeneCards Identifiers for GRINA Gene
- GC08U990038
- GC08M145371
- GC08P144839
- GC08P145170
- GC08P145171
- GC08P145136
- GC08P145064
- GC08P140305
Summaries for GRINA Gene
GeneCards Summary for GRINA Gene
GRINA (Glutamate Ionotropic Receptor NMDA Type Subunit Associated Protein 1) is a Protein Coding gene. Among its related pathways are CREB Pathway and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include ion channel binding. An important paralog of this gene is FAIM2.
UniProtKB/Swiss-Prot Summary for GRINA Gene
-
Potential apoptotic regulator.
Additional gene information for GRINA Gene
- HGNC(4589)
- Entrez Gene(2907)
- Ensembl(ENSG00000178719)
- OMIM(138251)
- UniProtKB(Q7Z429)
- Open Targets Platform(ENSG00000178719)
- Search for GRINA at DataMed
- Search for GRINA at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GRINA Gene
Genomics for GRINA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GRINA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GRINA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GRINA
- Top Transcription factor binding sites by QIAGEN in the GRINA gene promoter:
-
- c-Myc
- Max1
- MyoD
Genomic Locations for GRINA Gene
Genomic Locations for GRINA Gene
- chr8:143,990,056-143,993,415
- (GRCh38/hg38)
- Size:
- 3,360 bases
- Orientation:
- Plus strand
- chr8:145,064,226-145,067,583
- (GRCh37/hg19)
- Size:
- 3,358 bases
- Orientation:
- Plus strand
Genomic View for GRINA Gene
Genes around GRINA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.3 by HGNC
- 8q24.3 by Entrez Gene
- 8q24.3 by Ensembl
GRINA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GRINA Gene
Proteins for GRINA Gene
-
Protein details for GRINA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z429-LFG1_HUMAN
- Recommended name:
- Protein lifeguard 1
- Protein Accession:
- Q7Z429
- B3KXM7
- O43836
- Q8IVW7
Protein attributes for GRINA Gene
- Size:
- 371 amino acids
- Molecular mass:
- 41203 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAB94292.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for GRINA Gene
Post-translational modifications for GRINA Gene
Other Protein References for GRINA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GRINA
- Novus Biologicals Antibodies for GRINA
- Invitrogen Antibodies for GRINA (AFLGC-GRINA)
- antibodies-online: Show 19 available GRINA Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for GRINA
- Search Origene for MassSpec and Protein Over-expression Lysates for GRINA
- Origene Custom Protein Services for GRINA
-
Signalway Proteins for GRINA
Assay Products
- G Biosciences Immunotag™ Protein lifeguard 1 ELISA Kit
- antibodies-online: Show 10 available GRINA Elisa Kits ranked by validation data
- Compare Top GRINA Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for GRINA Gene
Domains & Families for GRINA Gene
Gene Families for GRINA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for GRINA Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for GRINA Gene
- GenScript: Design optimal peptide antigens:
-
- Putative MAPK-activating protein PM02 (GRINA_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q7Z429- Family:
-
- Belongs to the BI1 family. LFG subfamily.
Function for GRINA Gene
Molecular function for GRINA Gene
- UniProtKB/Swiss-Prot Function:
- Potential apoptotic regulator.
- GENATLAS Biochemistry:
- N-methyl D-aspartate receptor,glutamate receptor,glutamate binding subunit
Phenotypes From GWAS Catalog for GRINA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0044325 | ion channel binding | IEA | -- |
Phenotypes for GRINA Gene
- MGI mutant phenotypes for GRINA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for GRINA:
-
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Decreased Salmonella enterica Typhimurium invasion
- Strongly decreased CFP-tsO45G cell surface transport
- Increased shRNA abundance (Z-score > 2)
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Decreased and increased HIV-LTR-beta-galactosidase protein expression
Animal Models for GRINA Gene
- MGI Knock Outs for GRINA:
-
- Grina Grina<tm1.1Ldh>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GRINA - Select products 50% OFF >
- * GRINA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for GRINA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GRINA
-
Santa Cruz Biotechnology (SCBT) CRISPR for GRINA
miRNA for GRINA Gene
- miRTarBase miRNAs that target GRINA
-
- mmu-miR-24-3p (MIRT013753)
- hsa-miR-7-5p (MIRT025808)
- hsa-miR-296-3p (MIRT038514)
- hsa-miR-106b-3p (MIRT038571)
- hsa-miR-125b-5p (MIRT046002)
- hsa-miR-34a-5p (MIRT047387)
- hsa-miR-10b-5p (MIRT047457)
- hsa-miR-3127-5p (MIRT476056)
- hsa-miR-4290 (MIRT476057)
- hsa-miR-4518 (MIRT476058)
- hsa-miR-6859-3p (MIRT476059)
- hsa-miR-1266-5p (MIRT476060)
- hsa-miR-3918 (MIRT476061)
- hsa-miR-383-3p (MIRT476062)
- hsa-miR-3065-3p (MIRT476063)
- hsa-miR-548ao-3p (MIRT476064)
- hsa-miR-3667-5p (MIRT476065)
- hsa-miR-24-3p (MIRT476066)
- hsa-miR-4665-5p (MIRT489757)
- hsa-miR-1275 (MIRT489758)
- hsa-miR-4472 (MIRT489759)
- hsa-miR-4447 (MIRT489760)
- hsa-miR-92a-2-5p (MIRT489761)
- hsa-miR-5010-5p (MIRT489762)
- hsa-miR-4525 (MIRT489763)
- hsa-miR-6870-5p (MIRT489764)
- hsa-miR-7111-5p (MIRT489765)
- hsa-miR-5698 (MIRT489766)
- hsa-miR-4723-5p (MIRT489767)
- hsa-miR-625-5p (MIRT489768)
- hsa-miR-6825-5p (MIRT489769)
- hsa-miR-939-5p (MIRT489770)
- hsa-miR-1343-5p (MIRT489771)
- hsa-miR-6780b-5p (MIRT489772)
- hsa-miR-4725-3p (MIRT489773)
- hsa-miR-4271 (MIRT489774)
- hsa-miR-6799-5p (MIRT489775)
- hsa-miR-6827-5p (MIRT489776)
- hsa-miR-4747-5p (MIRT489777)
- hsa-miR-5196-5p (MIRT489778)
- hsa-miR-6851-5p (MIRT489779)
- hsa-miR-3689d (MIRT489780)
- hsa-miR-3202 (MIRT489781)
- hsa-miR-6134 (MIRT489782)
- hsa-miR-3179 (MIRT489783)
- hsa-miR-6794-5p (MIRT489784)
- hsa-miR-4716-3p (MIRT489785)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GRINA
- Browse OriGene Inhibitory RNA Products For GRINA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GRINA
Clone Products
- Applied Biological Materials (abm): Clones for GRINA - Select products 50% OFF >
- * GRINA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for GRINA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GRINA
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GRINA Gene
Localization for GRINA Gene
Subcellular locations from UniProtKB/Swiss-Prot for GRINA Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| endoplasmic reticulum | 3 |
| golgi apparatus | 3 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
- Cytosol (2)
- Nucleoli fibrillar center (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for GRINA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Dopamine-DARPP32 Feedback onto cAMP Pathway |
Dopamine-DARPP32 Feedback onto cAMP Pathway
-
|
|
| 2 | fMLP Pathway |
Huntington's Disease Pathway
.31
|
|
| 3 | CREB Pathway |
Intracellular Calcium Signaling
.50
|
|
| 4 | Neuropathic Pain-Signaling in Dorsal Horn Neurons |
Neuropathic Pain-Signaling in Dorsal Horn Neurons
.47
|
|
| 5 | nNOS Signaling at Neuronal Synapses |
nNOS Signaling at Neuronal Synapses
-
|
|
Pathways by source for GRINA Gene
7 Qiagen pathways for GRINA Gene
- Dopamine-DARPP32 Feedback onto cAMP Pathway
- Huntington's Disease Pathway
- Intracellular Calcium Signaling
- Neuropathic Pain-Signaling in Dorsal Horn Neurons
- nNOS Signaling at Neuronal Synapses
Interacting Proteins for GRINA Gene
Selected Interacting proteins:
ENSP00000314380
Q7Z429-LFG1_HUMAN
for GRINA Gene via
STRING
UniProtKB
IID
GPS-Prot Interaction Network for GRINA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0032469 | endoplasmic reticulum calcium ion homeostasis | IEA | -- |
| GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | IEA | -- |
No data available for SIGNOR curated interactions for GRINA Gene
Transcripts for GRINA Gene
mRNA/cDNA for GRINA Gene
- 2 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000313269 1968 nts (view in UCSC)
- ENST00000395068 1858 nts (view in UCSC)
- ENST00000525513 796 nts (view in UCSC)
- ENST00000527194 806 nts (view in UCSC)
- ENST00000529301 1075 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GRINA - Select products 50% OFF >
- * GRINA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for GRINA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GRINA
-
Santa Cruz Biotechnology (SCBT) CRISPR for GRINA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GRINA
- Browse OriGene Inhibitory RNA Products For GRINA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GRINA
Clone Products
- Applied Biological Materials (abm): Clones for GRINA - Select products 50% OFF >
- * GRINA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for GRINA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GRINA
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||
| SP9: |
Relevant External Links for GRINA Gene
- GeneLoc Exon Structure for
- GRINA
Expression for GRINA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for GRINA Gene
This gene is overexpressed in Whole Blood (x7.1).
This gene is overexpressed in Urine (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GRINA Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GRINA
SOURCE GeneReport for Unigene cluster for GRINA Gene:
Hs.594634Evidence on tissue expression from TISSUES for GRINA Gene
- Pancreas(4.8)
- Lung(4.6)
- Kidney(4.6)
- Liver(4.6)
- Nervous system(4.5)
- Skin(3.8)
- Eye(3.3)
- Muscle(2.4)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for GRINA
-
OriGene qPCR primer pairs and template standards for GRINA
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GRINA Gene
Orthologs for GRINA Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GRINA 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GRINA 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GRINA 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Grina 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Grina 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | GRINA 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | GRINA 31 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | grina-prov 30 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.1396 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:136572 30 |
|
||
| GRINA 31 |
|
OneToOne | |||
| zgc64102 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Nmda1 30 |
|
||
| CG3814 31 |
|
ManyToMany | |||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BXI1 31 |
|
OneToMany |
- Species where no ortholog for GRINA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GRINA Gene
- ENSEMBL:
- Gene Tree for GRINA (if available)
- TreeFam:
- Gene Tree for GRINA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GRINA: view image
Paralogs for GRINA Gene
Variants for GRINA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GRINA Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17854152 | - | p.Ser107Asn |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv12431n54 | CNV | loss | 21841781 |
| dgv12432n54 | CNV | loss | 21841781 |
| dgv12433n54 | CNV | gain | 21841781 |
| dgv906n27 | CNV | loss | 19166990 |
| nsv1075597 | CNV | deletion | 25765185 |
| nsv1161815 | CNV | deletion | 26073780 |
| nsv470249 | CNV | loss | 18288195 |
| nsv470250 | CNV | gain | 18288195 |
| nsv515809 | CNV | gain+loss | 19592680 |
| nsv612906 | CNV | loss | 21841781 |
| nsv612907 | CNV | gain+loss | 21841781 |
| nsv612914 | CNV | loss | 21841781 |
| nsv6445 | CNV | insertion | 18451855 |
| nsv950015 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
48.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.54;
11.65% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GRINA Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GRINA Gene
Disorders for GRINA Gene
Additional Disease Information for GRINA
No disorders were found for GRINA Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GRINA Gene
Publications for GRINA Gene
- Mapping of the human NMDA receptor subunit (NMDAR1) and the proposed NMDA receptor glutamate-binding subunit (NMDARA1) to chromosomes 9q34.3 and chromosome 8, respectively. (PMID: 8406459) Collins C … Hayden MR (Genomics 1993) 2 3 4 23
- Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PMID: 12761501) Matsuda A … Sugano S (Oncogene 2003) 3 4
- Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex. (PMID: 1719427) Kumar KN … Michaelis EK (Nature 1991) 2 3
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci. (PMID: 30730609) Rice SJ … Loughlin J (Arthritis & rheumatology (Hoboken, N.J.) 2019) 3
ExternalLinks
Products for GRINA Gene
- Custom Antibody ServicesOriGene Antibodies for GRINA
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for GRINA
- Search Origene for MassSpec and Protein Over-expression Lysates for GRINA
- Origene Custom Protein Services for GRINA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GRINA
- Browse OriGene Inhibitory RNA Products For GRINA
- OriGene qPCR primer pairs for GRINA
- OriGene qPCR primer pairs and template standards for GRINA
- OriGene CRISPR knockouts for GRINA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For GRINA
- Sino Biological Human cDNA Clone for GRINA
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for GRINA
- Novus Biologicals proteins and lysates for GRINA
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for GRINA (AFLGC-GRINA)
- VectorBuilder Custom and pre-made DNA vectors for GRINA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GRINA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GRINA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GRINA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GRINA
- antibodies-online: Show 19 available GRINA Antibodies ranked by validation data
- antibodies-online: Show 10 available GRINA Elisa Kits ranked by validation data
- Compare Top GRINA Elisa Kits
- Quality Products:
- antibodies-online: Search results for available GRINA related products ranked by validation data
- Horizon Cell Lines for GRINA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GRINA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GRINA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GRINA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GRINA
- Signalway Proteins for GRINA
Sources for GRINA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB