Aliases for GRID1 Gene
External Ids for GRID1 Gene
Previous GeneCards Identifiers for GRID1 Gene
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
GeneCards Summary for GRID1 Gene
GRID1 (Glutamate Ionotropic Receptor Delta Type Subunit 1) is a Protein Coding gene. Diseases associated with GRID1 include Rett Syndrome and Pitt-Hopkins-Like Syndrome 1. Among its related pathways are Peptide ligand-binding receptors and MECP2 and Associated Rett Syndrome. Gene Ontology (GO) annotations related to this gene include ionotropic glutamate receptor activity and extracellularly glutamate-gated ion channel activity. An important paralog of this gene is GRID2.
UniProtKB/Swiss-Prot Summary for GRID1 Gene
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.