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Aliases for GRIA4 Gene

Aliases for GRIA4 Gene

  • Glutamate Ionotropic Receptor AMPA Type Subunit 4 2 3 5
  • Glutamate Receptor, Ionotrophic, AMPA 4 2 3
  • AMPA-Selective Glutamate Receptor 4 3 4
  • GluR-4 3 4
  • GluR-D 3 4
  • GLUR4 3 4
  • GluA4 3 4
  • Glutamate Receptor, Ionotropic, AMPA 4 3
  • Glutamate Receptor Ionotropic, AMPA 4 4
  • Glutamate Receptor 4 3
  • GLUR4C 3
  • GLURD 3

External Ids for GRIA4 Gene

Previous HGNC Symbols for GRIA4 Gene

  • GLUR4

Previous GeneCards Identifiers for GRIA4 Gene

  • GC11P107674
  • GC11P106838
  • GC11P105018
  • GC11P104986
  • GC11P101412

Summaries for GRIA4 Gene

Entrez Gene Summary for GRIA4 Gene

  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]

GeneCards Summary for GRIA4 Gene

GRIA4 (Glutamate Ionotropic Receptor AMPA Type Subunit 4) is a Protein Coding gene. Diseases associated with GRIA4 include Schizophrenia. Among its related pathways are Circadian entrainment and Post NMDA receptor activation events. Gene Ontology (GO) annotations related to this gene include ionotropic glutamate receptor activity and AMPA glutamate receptor activity. An important paralog of this gene is GRIA2.

UniProtKB/Swiss-Prot for GRIA4 Gene

  • Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Tocris Summary for GRIA4 Gene

  • AMPA receptors are members of the ionotropic class of glutamate receptors, which also includes NMDA and kainate receptors. AMPA receptors mediate fast excitatory synaptic transmission and play a role in hippocampal synaptic long-term potentiation and depression.

Gene Wiki entry for GRIA4 Gene

Additional gene information for GRIA4 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GRIA4 Gene

Genomics for GRIA4 Gene

GeneHancer (GH) Regulatory Elements for GRIA4 Gene

Promoters and enhancers for GRIA4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I105609 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 550.8 +1.3 1295 3.2 CTCF MXI1 GLIS2 POLR2A GLIS1 CTBP2 POU5F1 EZH2 ZBTB20 GRIA4 AASDHPPT HSPD1P13
GH11I105610 Enhancer 0.6 Ensembl ENCODE 550.8 -0.5 -497 0.2 CTCF SMC3 RAD21 GRIA4 LOC105369468
GH11I105515 Enhancer 0.8 ENCODE 7.3 -94.0 -93951 1.6 HDAC1 PKNOX1 ATF1 TAF9B RB1 NFRKB POLR2B ATF7 SMARCA5 PHF21A GRIA4 LOC105369468 PIR34838
GH11I105243 Enhancer 1.1 FANTOM5 Ensembl ENCODE 4.2 -365.3 -365296 2.9 JUN MAX CEBPB EP300 BRCA1 SP1 MAFF JUND POLR2A STAT3 CARD17 GRIA4 CASP1 CARD16 CASP4 CASP5 ENSG00000255336 GC11P105198 LOC105369468
GH11I105642 Enhancer 0.3 FANTOM5 12.8 +32.6 32552 0 GRIA4 MSANTD4 HSPD1P13
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GRIA4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GRIA4 gene promoter:

Genomic Locations for GRIA4 Gene

Genomic Locations for GRIA4 Gene
chr11:105,609,994-105,982,092
(GRCh38/hg38)
Size:
372,099 bases
Orientation:
Plus strand
chr11:105,480,721-105,852,819
(GRCh37/hg19)

Genomic View for GRIA4 Gene

Genes around GRIA4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GRIA4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GRIA4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GRIA4 Gene

Proteins for GRIA4 Gene

  • Protein details for GRIA4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P48058-GRIA4_HUMAN
    Recommended name:
    Glutamate receptor 4
    Protein Accession:
    P48058
    Secondary Accessions:
    • Q86XE8

    Protein attributes for GRIA4 Gene

    Size:
    902 amino acids
    Molecular mass:
    100871 Da
    Quaternary structure:
    • Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. Interacts with EPB41L1 via its C-terminus (By similarity). Found in a complex with GRIA1, GRIA2, GRIA3, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with CACNG5 and PRKCG (By similarity).
    Miscellaneous:
    • The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds AMPA (quisqualate) > glutamate > kainate.

    Alternative splice isoforms for GRIA4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GRIA4 Gene

Post-translational modifications for GRIA4 Gene

  • Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-611 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-837 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity).
  • Phosphorylated at Ser-862 by PRKCG; phosphorylation increases plasma membrane-associated GRI4 expression.
  • Glycosylation at isoforms=256, isoforms=2258, isoforms=2371, posLast=407407, and isoforms=2414
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GRIA4 Gene

Domains & Families for GRIA4 Gene

Gene Families for GRIA4 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted membrane proteins
  • Predicted secreted proteins

Suggested Antigen Peptide Sequences for GRIA4 Gene

Graphical View of Domain Structure for InterPro Entry

P48058

UniProtKB/Swiss-Prot:

GRIA4_HUMAN :
  • The M4 transmembrane segment mediates tetramerization and is required for cell surface expression.
  • Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA4 subfamily.
Domain:
  • The M4 transmembrane segment mediates tetramerization and is required for cell surface expression.
Family:
  • Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA4 subfamily.
genes like me logo Genes that share domains with GRIA4: view

Function for GRIA4 Gene

Molecular function for GRIA4 Gene

GENATLAS Biochemistry:
glutamate receptor,subunit 4,ionotropic,AMPA (amino-3-hydroxy 5 methyl-isoxazole-propionic) class,with flip and flop isoforms,mediating the fast component of excitatory post synaptic currents in the central nervous system,interacting with and signaling through the protein-kinase LYN
UniProtKB/Swiss-Prot Function:
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Phenotypes From GWAS Catalog for GRIA4 Gene

Gene Ontology (GO) - Molecular Function for GRIA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004970 ionotropic glutamate receptor activity IEA,ISS --
GO:0004971 AMPA glutamate receptor activity IDA 21172611
GO:0005216 ion channel activity IEA --
GO:0005231 excitatory extracellular ligand-gated ion channel activity TAS --
GO:0005234 extracellularly glutamate-gated ion channel activity IEA --
genes like me logo Genes that share ontologies with GRIA4: view
genes like me logo Genes that share phenotypes with GRIA4: view

Animal Models for GRIA4 Gene

MGI Knock Outs for GRIA4:

Animal Model Products

  • Taconic Biosciences Mouse Models for GRIA4

miRNA for GRIA4 Gene

miRTarBase miRNAs that target GRIA4

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GRIA4 Gene

Localization for GRIA4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GRIA4 Gene

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GRIA4 gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for GRIA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030054 cell junction IEA --
GO:0030425 dendrite IEA --
genes like me logo Genes that share ontologies with GRIA4: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for GRIA4 Gene

Pathways & Interactions for GRIA4 Gene

genes like me logo Genes that share pathways with GRIA4: view

SIGNOR curated interactions for GRIA4 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for GRIA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA,TAS 8589990
GO:0006811 ion transport IEA --
GO:0007215 glutamate receptor signaling pathway TAS 8589990
GO:0034220 ion transmembrane transport IEA --
GO:0035235 ionotropic glutamate receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with GRIA4: view

Drugs & Compounds for GRIA4 Gene

(44) Drugs for GRIA4 Gene - From: DrugBank, ApexBio, DGIdb, IUPHAR, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ethanol Approved Pharma Target 2326
Cyclothiazide Approved Pharma Positive, Allosteric regulator, inhibitor 0
Piracetam Approved, Investigational Pharma Positive, Allosteric regulator 176
Glutamic Acid Approved Nutra Full agonist, Agonist, Target 251
Perampanel Approved Pharma AMPA-type glutamate receptor antagonist 0

(4) Additional Compounds for GRIA4 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(4) Tocris Compounds for GRIA4 Gene

Compound Action Cas Number
(R)-AMPA Inactive isomer of (RS)-AMPA (Cat. No. 0169) 83654-13-1
(RS)-AMPA Selective AMPA agonist 74341-63-2
L-Quisqualic acid AMPA/group I mGlu agonist 52809-07-1
Piracetam Nootropic; modulates Na+-flux at AMPA receptors 7491-74-9

(8) ApexBio Compounds for GRIA4 Gene

Compound Action Cas Number
ADX-47273 851881-60-2
IEM 1754 dihydrobroMide 162831-31-4
Ifenprodil Tartrate NMDA receptor antagonist 23210-58-4
Latrepirdine Brain cell death inhibitor 97657-92-6
NMDA (N-Methyl-D-aspartic acid) NMDA receptor agonist 6384-92-5
VU 0361737 MGlu4 receptor allosteric modulator 1161205-04-4
VU 0364439 Positive allosteric mGluR-4 modulator 1246086-78-1
VU 0364770 61350-00-3
genes like me logo Genes that share compounds with GRIA4: view

Drug Products

Transcripts for GRIA4 Gene

mRNA/cDNA for GRIA4 Gene

(12) REFSEQ mRNAs :
(15) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GRIA4 Gene

Glutamate receptor, ionotropic, AMPA 4:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GRIA4 Gene

No ASD Table

Relevant External Links for GRIA4 Gene

GeneLoc Exon Structure for
GRIA4
ECgene alternative splicing isoforms for
GRIA4

Expression for GRIA4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GRIA4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GRIA4 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x9.0), Brain - Cerebellum (x7.4), Brain - Frontal Cortex (BA9) (x5.2), and Brain - Anterior cingulate cortex (BA24) (x4.9).

Protein differential expression in normal tissues from HIPED for GRIA4 Gene

This gene is overexpressed in Vitreous humor (44.6), Cerebrospinal fluid (8.1), and Brain (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GRIA4 Gene



Protein tissue co-expression partners for GRIA4 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GRIA4 Gene:

GRIA4

SOURCE GeneReport for Unigene cluster for GRIA4 Gene:

Hs.503743

Evidence on tissue expression from TISSUES for GRIA4 Gene

  • Nervous system(4.9)
  • Eye(2.7)
genes like me logo Genes that share expression patterns with GRIA4: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GRIA4 Gene

Orthologs for GRIA4 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GRIA4 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GRIA4 34
  • 98 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GRIA4 33 34
  • 97.06 (n)
oppossum
(Monodelphis domestica)
Mammalia GRIA4 34
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GRIA4 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GRIA4 33 34
  • 94.16 (n)
rat
(Rattus norvegicus)
Mammalia Gria4 33
  • 91.65 (n)
mouse
(Mus musculus)
Mammalia Gria4 33 16 34
  • 90.91 (n)
chicken
(Gallus gallus)
Aves GRIA4 33 34
  • 89.17 (n)
lizard
(Anolis carolinensis)
Reptilia GRIA4 34
  • 91 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii gria4a 34
  • 89 (a)
OneToMany
gria4b 34
  • 89 (a)
OneToMany
Dr.13666 33
fruit fly
(Drosophila melanogaster)
Insecta CG11155 35
  • 51 (a)
Glu-RI 35
  • 41 (a)
CG9935 35
  • 40 (a)
Glu-RIB 35
  • 36 (a)
CG5621 35
  • 34 (a)
Kai-RIA 35
  • 34 (a)
Glu-RIIA 35
  • 32 (a)
CG4226 35
  • 28 (a)
CG15627 35
  • 27 (a)
worm
(Caenorhabditis elegans)
Secernentea glr-1 35
  • 49 (a)
glr-4 35
  • 32 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons GLR3.4 33
  • 40.86 (n)
rice
(Oryza sativa)
Liliopsida Os06g0680500 33
  • 38.36 (n)
Species where no ortholog for GRIA4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for GRIA4 Gene

ENSEMBL:
Gene Tree for GRIA4 (if available)
TreeFam:
Gene Tree for GRIA4 (if available)

Paralogs for GRIA4 Gene

Variants for GRIA4 Gene

Sequence variations from dbSNP and Humsavar for GRIA4 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000036255 -- 105,669,195(+) C/G genic_upstream_transcript_variant, intron_variant
rs1000037312 -- 105,911,644(+) G/C intron_variant
rs1000039897 -- 105,846,405(+) G/T genic_upstream_transcript_variant, intron_variant
rs1000041232 -- 105,896,419(+) TTTAGTTTAGTT/TTTAGTT intron_variant
rs1000041875 -- 105,710,814(+) T/A/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GRIA4 Gene

Variant ID Type Subtype PubMed ID
dgv23n6 CNV deletion 16902084
esv2000018 CNV deletion 18987734
esv2520318 CNV deletion 19546169
esv2599683 CNV deletion 19546169
esv2658816 CNV deletion 23128226
esv2669612 CNV deletion 23128226
esv2672300 CNV deletion 23128226
esv2745021 CNV deletion 23290073
esv2745022 CNV deletion 23290073
esv2745023 CNV deletion 23290073
esv3304515 CNV mobile element insertion 20981092
esv3417415 CNV insertion 20981092
esv3548298 CNV deletion 23714750
esv3548302 CNV deletion 23714750
esv3579896 CNV loss 25503493
esv3627616 CNV loss 21293372
esv3627617 CNV loss 21293372
esv3627619 CNV loss 21293372
esv3627620 CNV loss 21293372
esv3892096 CNV gain 25118596
esv4809 CNV loss 18987735
esv6086 CNV loss 19470904
esv9295 CNV loss 19470904
nsv1052674 CNV loss 25217958
nsv1053687 CNV loss 25217958
nsv1075434 CNV duplication 25765185
nsv1075839 CNV duplication 25765185
nsv1134173 CNV deletion 24896259
nsv1144590 CNV deletion 24896259
nsv39184 CNV deletion 16902084
nsv472 CNV insertion 18451855
nsv832256 CNV gain 17160897
nsv832257 CNV loss 17160897

Variation tolerance for GRIA4 Gene

Residual Variation Intolerance Score: 3.06% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.16; 23.50% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GRIA4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GRIA4

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GRIA4 Gene

Disorders for GRIA4 Gene

MalaCards: The human disease database

(1) MalaCards diseases for GRIA4 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
schizophrenia
  • sczd
- elite association - COSMIC cancer census association via MalaCards
Search GRIA4 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GRIA4

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with GRIA4: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GRIA4 Gene

Publications for GRIA4 Gene

  1. No genetic association between polymorphisms in the AMPA receptor subunit GluR4 gene (GRIA4) and schizophrenia in the Chinese population. (PMID: 15450689) Guo S … He L (Neuroscience letters 2004) 3 22 44 58
  2. Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: linkage disequilibrium mapping using SNPs evenly distributed across the gene region. (PMID: 12497607) Makino C … Fukumaki Y (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003) 3 22 44 58
  3. Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. (PMID: 21172611) Kato AS … Bredt DS (Neuron 2010) 3 4 58
  4. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PMID: 19086053) Gratacòs M … Psychiatric Genetics Network Group (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009) 3 44 58
  5. Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. (PMID: 19156168) Need AC … Goldstein DB (European journal of human genetics : EJHG 2009) 3 44 58

Products for GRIA4 Gene

Sources for GRIA4 Gene

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