Aliases for GRB14 Gene
Aliases for GRB14 Gene
External Ids for GRB14 Gene
- HGNC: 4565
- Entrez Gene: 2888
- Ensembl: ENSG00000115290
- OMIM: 601524
- UniProtKB: Q14449
Previous GeneCards Identifiers for GRB14 Gene
- GC02M163404
- GC02M163891
- GC02M165313
- GC02M165551
- GC02M165174
- GC02M165057
- GC02M157231
- GC02M165350
Summaries for GRB14 Gene
-
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
GeneCards Summary for GRB14 Gene
GRB14 (Growth Factor Receptor Bound Protein 14) is a Protein Coding gene. Among its related pathways are Cell surface interactions at the vascular wall and Immune response IL-23 signaling pathway. Gene Ontology (GO) annotations related to this gene include SH3/SH2 adaptor activity. An important paralog of this gene is GRB10.
UniProtKB/Swiss-Prot for GRB14 Gene
-
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GRB14 Gene
Genomics for GRB14 Gene
GeneHancer (GH) Regulatory Elements for GRB14 Gene
Promoters and enhancers for GRB14 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J164620 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE | 650.7 | +0.4 | 449 | 1.6 | ARID4B KLF17 SIN3A KLF14 ZNF48 YY1 ZNF335 GLIS2 ELK1 EGR1 | GRB14 SLC38A11 GC02M164552 | |
| GH02J164622 | Promoter | 0.9 | EPDnew | 650.7 | -0.6 | -609 | 0.1 | FOXA2 TAF1 RXRA REST RAD21 FOXA1 YY1 SP1 JUND ATF3 | GRB14 ENSG00000224331 | |
| GH02J164567 | Enhancer | 0.7 | ENCODE | 16 | +53.9 | 53901 | 1.5 | FOXA2 TAF1 CEBPG ZNF7 YY1 GATA3 NR2F6 MAFK HOMEZ GATAD2A | GRB14 EIF3EP3 GC02M164552 ENSG00000237844 | |
| GH02J164661 | Enhancer | 0.7 | ENCODE | 10.5 | -39.7 | -39716 | 0.2 | PKNOX1 FOXA2 CLOCK CEBPG RFX5 YY1 CTBP1 GATA3 EGR1 FOS | ENSG00000224331 SNORA70F GRB14 COBLL1 | |
| GH02J163805 | Enhancer | 0.6 | VISTA UCNEbase | 5.1 | +816.3 | 816342 | 0.8 | GRB14 GC02P163800 GC02P164066 ENSG00000237844 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around GRB14 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the GRB14 gene promoter:
-
- AREB6
- Lmo2
- Egr-2
- AML1a
- C/EBPalpha
- FOXL1
- HFH-3
- FOXI1
Regulatory Element Products
Genomic Locations for GRB14 Gene
Genomic Locations for GRB14 Gene
- chr2:164,492,406-164,621,850
- (GRCh38/hg38)
- Size:
- 129,445 bases
- Orientation:
- Minus strand
- chr2:165,349,322-165,478,360
- (GRCh37/hg19)
- Size:
- 129,039 bases
- Orientation:
- Minus strand
Genomic View for GRB14 Gene
Genes around GRB14 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q24.3 by Entrez Gene
- 2q24.3 by HGNC
- 2q24.3 by Ensembl
GRB14 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GRB14 Gene
Proteins for GRB14 Gene
-
Protein details for GRB14 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14449-GRB14_HUMAN
- Recommended name:
- Growth factor receptor-bound protein 14
- Protein Accession:
- Q14449
- B7Z7F9
- Q7Z6I1
Protein attributes for GRB14 Gene
- Size:
- 540 amino acids
- Molecular mass:
- 60988 Da
- Quaternary structure:
-
- Interacts with the cytoplasmic domain of the autophosphorylated insulin receptor (INSR), through the SH2 domain (By similarity). Interacts with GRB14 (via BPS domain); this interaction protects the tyrosines in the activation loop on INSR from dephosphorylation. Binds to the ankyrin repeat region of TNKS2 via its N-terminus. Interacts with activated NRAS. Interacts (via SH2 domain) with TEK/TIE2 (tyrosine phosphorylated).
Protein Expression for GRB14 Gene
Post-translational modifications for GRB14 Gene
- Phosphorylated on serine residues. Phosphorylated on tyrosine residues by TEK/TIE2.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for GRB14 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GRB14
- Novus Biologicals Antibodies for GRB14
- Invitrogen Antibodies for GRB14 (AFLGC-GRB14)
- GeneTex GRB14 Antibody for GRB14
Protein Products
-
OriGene Purified Proteins for GRB14
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- antibodies-online: Search results for 5 available GRB14 Proteins ranked by validation data
- Compare Top GRB14 Proteins
-
Quality Products:
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-
Abcam proteins for GRB14
Assay Products
No data available for DME Specific Peptides for GRB14 Gene
Domains & Families for GRB14 Gene
Gene Families for GRB14 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for GRB14 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for GRB14 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14449UniProtKB/Swiss-Prot:
GRB14_HUMAN :- The PH domain binds relatively non-specifically and with low affinity to several phosphoinositides, the best binder being PI(3,4,5)P3.
- Belongs to the GRB7/10/14 family.
- Domain:
-
- The PH domain binds relatively non-specifically and with low affinity to several phosphoinositides, the best binder being PI(3,4,5)P3.
- Family:
-
- Belongs to the GRB7/10/14 family.
Function for GRB14 Gene
Molecular function for GRB14 Gene
- UniProtKB/Swiss-Prot Function:
- Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
- GENATLAS Biochemistry:
- growth factor receptor bound protein 14,homolog to C elegans mig 10 gene,widely expressed,involved in signal transduction
Phenotypes From GWAS Catalog for GRB14 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | IEA | -- |
| GO:0030971 | receptor tyrosine kinase binding | IPI | 16246733 |
| GO:0042802 | identical protein binding | IMP | 16246733 |
| GO:0042803 | protein homodimerization activity | IMP | 16246733 |
Phenotypes for GRB14 Gene
- MGI mutant phenotypes for GRB14:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for GRB14:
Animal Models for GRB14 Gene
- MGI Knock Outs for GRB14:
-
- Grb14 Grb14<tm1Daly>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
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-
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- Overview of 116 available GRB14 gene related products
- Applied Biological Materials CRISPR for GRB14
-
Vectors and viruses for KO, Activation, Repression, and more
-
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miRNA for GRB14 Gene
- miRTarBase miRNAs that target GRB14
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- Overview of 116 available GRB14 gene related products
Clone Products
- Sino Biological Human cDNA Clone for GRB14
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for GRB14
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GRB14 Gene
Localization for GRB14 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GRB14 Gene
- Cytoplasm. Endosome membrane; Peripheral membrane protein. Note=Upon insulin stimulation, translocates to the plasma membrane. {ECO:0000269 PubMed:15210700, ECO:0000269 PubMed:19648926}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| endosome | 4 |
| nucleus | 3 |
| cytoskeleton | 1 |
| peroxisome | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | 11278563 |
| GO:0005768 | endosome | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IDA | 11278563 |
| GO:0010008 | endosome membrane | IEA | -- |
Pathways & Interactions for GRB14 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Immune response IL-23 signaling pathway | ||
| 2 | Cell surface interactions at the vascular wall |
.01
|
|
| 3 | GPCR Pathway | ||
| 4 | BMP Pathway |
.36
|
|
| 5 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
Pathways by source for GRB14 Gene
4 BioSystems pathways for GRB14 Gene
3 Reactome pathways for GRB14 Gene
1 GeneGo (Thomson Reuters) pathway for GRB14 Gene
3 Qiagen pathways for GRB14 Gene
Interacting Proteins for GRB14 Gene
Selected Interacting proteins:
ENSP00000263915
Q14449-GRB14_HUMAN
for GRB14 Gene via
STRING
IID
MINT
GPS-Prot Interaction Network for GRB14
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0009967 | positive regulation of signal transduction | IEA | -- |
| GO:0046627 | negative regulation of insulin receptor signaling pathway | IMP | 16246733 |
| GO:0050900 | leukocyte migration | TAS | -- |
No data available for SIGNOR curated interactions for GRB14 Gene
Transcripts for GRB14 Gene
mRNA/cDNA for GRB14 Gene
- (6) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (69) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000424693 587 bps (uc061pbt.1)
- ENST00000469573 984 bps (uc061pbs.1)
- ENST00000446413 1435 bps (uc061pbr.1)
- ENST00000497306 406 bps (uc061pbq.1)
- ENST00000263915 2382 bps (uc002ucl.4)
Unigene Clusters for GRB14 Gene
CRISPR Products
-
OriGene CRISPR knockouts for GRB14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GRB14
- genomics-online: gRNA clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- Applied Biological Materials CRISPR for GRB14
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GRB14
- GenScript: Design CRISPR guide RNA sequences for GRB14
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GRB14
- Browse OriGene Inhibitory RNA Products For GRB14
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- genomics-online: shRNA clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
Clone Products
- Sino Biological Human cDNA Clone for GRB14
- Addgene plasmids for GRB14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GRB14
- Applied Biological Materials Clones for GRB14
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - |
Expression for GRB14 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Endothelium (Cardiovascular System)
- Neural Tube (Nervous System)
- Bone (Muscoskeletal System)
- Umbilical Cord (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for GRB14 Gene
This gene is overexpressed in Liver (x12.2), Kidney - Cortex (x4.9), and Adrenal Gland (x4.6).
This gene is overexpressed in Testis (45.3) and Liver (9.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GRB14 Gene
NURSA nuclear receptor signaling pathways regulating expression of GRB14 Gene:
GRB14SOURCE GeneReport for Unigene cluster for GRB14 Gene:
Hs.411881mRNA Expression by UniProt/SwissProt for GRB14 Gene:
Q14449-GRB14_HUMAN
Tissue specificity:
Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.
Evidence on tissue expression from TISSUES for GRB14 Gene
- Liver(4.4)
- Skin(4)
Primer Products
-
OriGene qPCR primer pairs for GRB14
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GRB14 Gene
Orthologs for GRB14 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GRB14 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | GRB14 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | GRB14 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | GRB14 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Grb14 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Grb14 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | GRB14 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | GRB14 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | GRB14 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | grb14 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100334415 33 |
|
||
| CABZ01083696.1 34 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | pico 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | mig-10 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10684 34 |
|
OneToMany |
- Species where no ortholog for GRB14 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for GRB14 Gene
- ENSEMBL:
- Gene Tree for GRB14 (if available)
- TreeFam:
- Gene Tree for GRB14 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GRB14: view image
Paralogs for GRB14 Gene
Variants for GRB14 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs747345020 | uncertain-significance, not specified | 164,494,433(-) | G/A | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1000034033 | -- | 164,573,216(-) | TCTCT/TCT | genic_upstream_transcript_variant, intron_variant | |
| rs1000048073 | -- | 164,511,115(-) | C/T | intron_variant | |
| rs1000070319 | -- | 164,564,266(-) | T/C | intron_variant | |
| rs1000081427 | -- | 164,599,586(-) | G/C | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3593219 | CNV | loss | 21293372 |
| nsv473323 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
57.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
13.08;
95.08% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GRB14 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GRB14 Gene
Disorders for GRB14 Gene
Additional Disease Information for GRB14
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for GRB14 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GRB14 Gene
Publications for GRB14 Gene
- Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14. (PMID: 19648926) Depetris RS … Hubbard SR (Nature structural & molecular biology 2009) 3 4 22 58
- Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. (PMID: 16246733) Depetris RS … Hubbard SR (Molecular cell 2005) 3 4 22 58
- The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. (PMID: 15210700) King CC … Newton AC (The Journal of biological chemistry 2004) 3 4 22 58
- Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. (PMID: 21874001) Kooner JS … Chambers JC (Nature genetics 2011) 3 44 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
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- Search GeneTex for Proteins for GRB14
- Horizon Cell Lines for GRB14
- genomics-online: cdna clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- orf clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- genomics-online: gRNA clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- genomics-online: primer clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- genomics-online: shRNA clones - Search results for 116 available GRB14 gene related products
- Overview of 116 available GRB14 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GRB14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GRB14
- GeneCopoeia miRNA 3'UTR Target clone products for GRB14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GRB14
Sources for GRB14 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt