Aliases for GRAMD4 Gene
External Ids for GRAMD4 Gene
Previous GeneCards Identifiers for GRAMD4 Gene
GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed 15565177]).[supplied by OMIM, Jan 2011]
GeneCards Summary for GRAMD4 Gene
GRAMD4 (GRAM Domain Containing 4) is a Protein Coding gene. Diseases associated with GRAMD4 include Lung Squamous Cell Carcinoma.
UniProtKB/Swiss-Prot Summary for GRAMD4 Gene
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (PubMed:15565177). Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity).