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GRAMD1B (GRAM Domain Containing 1B) is a Protein Coding gene. Among its related pathways are Ectoderm Differentiation. An important paralog of this gene is GRAMD1A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001786 | phosphatidylserine binding | ISS | -- |
GO:0008289 | lipid binding | IEA | -- |
GO:0015485 | cholesterol binding | ISS | -- |
GO:0070300 | phosphatidic acid binding | ISS | -- |
GO:0120020 | intermembrane cholesterol transfer activity | ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005789 | endoplasmic reticulum membrane | IEA,IDA | 30220461 |
GO:0005886 | plasma membrane | IEA,IDA | 30220461 |
GO:0016020 | membrane | IEA,HDA | 19946888 |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Ectoderm Differentiation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006869 | lipid transport | IEA | -- |
GO:0015918 | sterol transport | IEA | -- |
GO:0042632 | cholesterol homeostasis | ISS | -- |
GO:0071397 | cellular response to cholesterol | ISS | -- |
GO:0120009 | intermembrane lipid transfer | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
lithium | Experimental | Pharma | 0 |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GRAMD1B 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GRAMD1B 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GRAMD1B 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Gramd1b 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gramd1b 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | GRAMD1B 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | GRAMD1B 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | GRAMD1B 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | GRAMD1B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gramd1b 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | GRAMD1B (1 of 2) 31 |
|
OneToMany | |
gramd1b 30 |
|
||||
GRAMD1B (2 of 2) 31 |
|
OneToMany | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG30284 31 |
|
ManyToMany | |
CG34394 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | ZC328.3 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | -- 31 |
|
ManyToMany | |
YSP2 31 |
|
ManyToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv1010432 | CNV | deletion | 20482838 |
esv2603228 | CNV | insertion | 19546169 |
esv2663701 | CNV | deletion | 23128226 |
esv2759868 | CNV | loss | 17122850 |
esv3449847 | CNV | duplication | 20981092 |
nsv513339 | CNV | insertion | 21212237 |
nsv528 | CNV | insertion | 18451855 |
nsv556483 | CNV | gain | 21841781 |
nsv972081 | CNV | duplication | 23825009 |
No disorders were found for GRAMD1B Gene.