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GPR89A is a nearly identical copy of the GPR89B gene (MIM 612806).[supplied by OMIM, Jun 2009]
GPR89A (G Protein-Coupled Receptor 89A) is a Protein Coding gene. Diseases associated with GPR89A include Chromosome 1Q21.1 Deletion Syndrome, 1.35-Mb and Hemochromatosis, Type 2A. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and voltage-gated anion channel activity. An important paralog of this gene is GPR89B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005244 | voltage-gated ion channel activity | IEA | -- |
GO:0008308 | voltage-gated anion channel activity | IBA,IDA | 18794847 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000139 | Golgi membrane | IEA | -- |
GO:0005623 | cell | IEA | -- |
GO:0005794 | Golgi apparatus | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006811 | ion transport | IEA | -- |
GO:0015031 | protein transport | IEA | -- |
GO:0015698 | inorganic anion transport | IEA | -- |
GO:0034220 | ion transmembrane transport | IEA | -- |
GO:0034765 | regulation of ion transmembrane transport | IEA | -- |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GPR89B 30 31 |
|
OneToMany | |
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
LOC483157 30 |
|
||||
Cow (Bos Taurus) |
Mammalia | GPR89 30 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Rat (Rattus norvegicus) |
Mammalia | Gpr89b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Gpr89 30 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | GPR89 31 |
|
OneToMany | |
GPR89B 30 |
|
||||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100490107 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | GPR89A 31 |
|
OneToMany | |
si:ch73-390b10.2 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP011252 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG8090 30 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | CELE_Y75B8A.16 30 |
|
||
Y75B8A.16 31 |
|
ManyToMany | |||
C11H1.2 31 |
|
ManyToMany | |||
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | GTG2 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os04g0600800 30 |
|
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv331n100 | CNV | gain | 25217958 |
dgv332n100 | CNV | gain+loss | 25217958 |
dgv532n54 | CNV | gain | 21841781 |
dgv95e212 | CNV | gain | 25503493 |
esv3572342 | CNV | gain | 25503493 |
esv3587421 | CNV | loss | 21293372 |
esv3587422 | CNV | gain | 21293372 |
nsv1005055 | CNV | loss | 25217958 |
nsv1015025 | CNV | gain | 25217958 |
nsv469752 | CNV | loss | 16826518 |
nsv831392 | CNV | gain | 17160897 |
nsv946271 | CNV | duplication | 23825009 |
nsv946272 | CNV | duplication | 23825009 |
nsv998178 | CNV | loss | 25217958 |
Disorder | Aliases | PubMed IDs |
---|---|---|
chromosome 1q21.1 deletion syndrome, 1.35-mb |
|
|
hemochromatosis, type 2a |
|
|
thrombocytopenia-absent radius syndrome |
|
|
corneal endothelial dystrophy |
|
|
duodenal atresia |
|
|