Aliases for GPR88 Gene
External Ids for GPR88 Gene
Previous GeneCards Identifiers for GPR88 Gene
The protein encoded by this gene is a G protein-coupled receptor found almost exclusively in the striatum, a brain structure that controls motor function and cognition. Defects in this gene have been associated with chorea, speech delay, and learning difficulties, as well as some neuropsychiatric disorders. [provided by RefSeq, Mar 2017]
GeneCards Summary for GPR88 Gene
GPR88 (G Protein-Coupled Receptor 88) is a Protein Coding gene. Diseases associated with GPR88 include Chorea, Childhood-Onset, With Psychomotor Retardation. Among its related pathways are GPCRs, Other. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR75.
UniProtKB/Swiss-Prot Summary for GPR88 Gene
Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function.