Aliases for GPR84 Gene
External Ids for GPR84 Gene
Previous GeneCards Identifiers for GPR84 Gene
GeneCards Summary for GPR84 Gene
GPR84 (G Protein-Coupled Receptor 84) is a Protein Coding gene. Diseases associated with GPR84 include Alzheimer Disease 14. Among its related pathways are Signaling by GPCR and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is HTR4.
UniProtKB/Swiss-Prot Summary for GPR84 Gene
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.