Aliases for GPR65 Gene
External Ids for GPR65 Gene
Previous GeneCards Identifiers for GPR65 Gene
GeneCards Summary for GPR65 Gene
GPR65 (G Protein-Coupled Receptor 65) is a Protein Coding gene. Diseases associated with GPR65 include Gastric Cancer and B-Cell Childhood Acute Lymphoblastic Leukemia. Among its related pathways are Signaling by GPCR and RET signaling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR4.
UniProtKB/Swiss-Prot Summary for GPR65 Gene
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).