Aliases for GPR65 Gene
External Ids for GPR65 Gene
Previous GeneCards Identifiers for GPR65 Gene
GeneCards Summary for GPR65 Gene
GPR65 (G Protein-Coupled Receptor 65) is a Protein Coding gene. Diseases associated with GPR65 include Gastric Cancer and Panic Disorder. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR4.
UniProtKB/Swiss-Prot Summary for GPR65 Gene
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).