Aliases for GPR61 Gene
External Ids for GPR61 Gene
Previous GeneCards Identifiers for GPR61 Gene
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPR61 Gene
GPR61 (G Protein-Coupled Receptor 61) is a Protein Coding gene. Among its related pathways are GPCRs, Other. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR62.
UniProtKB/Swiss-Prot Summary for GPR61 Gene
Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). May be involved in the regulation of food intake and body weight (By similarity).