Aliases for GPR35 Gene
External Ids for GPR35 Gene
Previous GeneCards Identifiers for GPR35 Gene
GeneCards Summary for GPR35 Gene
GPR35 (G Protein-Coupled Receptor 35) is a Protein Coding gene. Diseases associated with GPR35 include Cholangitis, Primary Sclerosing and Short-Rib Thoracic Dysplasia 10 With Or Without Polydactyly. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is LPAR4.
UniProtKB/Swiss-Prot Summary for GPR35 Gene
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.