Aliases for GPR27 Gene
External Ids for GPR27 Gene
Previous GeneCards Identifiers for GPR27 Gene
GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]
GeneCards Summary for GPR27 Gene
GPR27 (G Protein-Coupled Receptor 27) is a Protein Coding gene. Diseases associated with GPR27 include Eyelid Disease. Among its related pathways are Signaling by GPCR and G alpha (s) signalling events. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR173.
UniProtKB/Swiss-Prot Summary for GPR27 Gene
Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.